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Navtemadlin (KRT-232) activity after failure of anti-PD-1/L1 therapy in patients (pts) with TP53WT Merkel cell carcinoma (MCC). |
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Consulting or Advisory Role - Castle Biosciences; Pfizer; Regeneron |
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Consulting or Advisory Role - Rain Therapeutics |
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Travel, Accommodations, Expenses - SpringWorks Therapeutics |
(OPTIONAL) Uncompensated Relationships - TRACON Pharma |
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Honoraria - Array BioPharma; Bristol Myers Squibb; EMD Serono; Exicure; Novartis; Pfizer; Sanofi/Regeneron |
Consulting or Advisory Role - Array BioPharma; Bristol-Myers Squibb; EMD Serono; Exicure; Novartis; Pfizer; Sanofi/Regeneron |
Research Funding - Bristol Myers Squibb Foundation (Inst); EMD Serono (Inst); exicure (Inst); Novartis (Inst); Pfizer (Inst); Sanofi/Regeneron (Inst) |
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Honoraria - 4SC; Amgen; Array BioPharma; Bristol-Myers Squibb; Daiichi Sankyo Japan; Immunocore; InflarxGmbH; LabCorp; Merck Serono; Merck Sharp & Dohme; Nektar; NeraCare GmbH; Novartis; Pfizer; Philogen; Pierre Fabre; Regeneron; Replimune; Roche/Genentech; Sandoz; Sanofi/Regeneron; Sun Pharma; Ultimovacs |
Consulting or Advisory Role - 4SC; Bristol-Myers Squibb; Merck Serono; Merck Sharp & Dohme; NEKTAR; Novartis; Pierre Fabre; Roche/Genentech; Sanofi/Regeneron |
Speakers' Bureau - Bristol-Myers Squibb; Merck KGaA; Merck Sharp & Dohme; Novartis; Pierre Fabre; Sanofi/Regeneron |
Research Funding - Amgen (Inst); Array BioPharma/Pfizer (Inst); Bristol-Myers Squibb (Inst); MSD Oncology (Inst); Novartis (Inst); Roche (Inst) |
Travel, Accommodations, Expenses - Bristol-Myers Squibb; Merck Serono; Merck Sharp & Dohme; Novartis; Pierre Fabre; Roche/Genentech; Sanofi/Regeneron |
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Consulting or Advisory Role - Genzyme; Instil Bio; Merck; Oncosec |
Research Funding - Biohaven Pharmaceuticals (Inst); Morphogenesis (Inst); Replimune (Inst); Shattuck Labs (Inst) |
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Consulting or Advisory Role - Bristol-Myers Squibb; Eisai; Merck; Pfizer; Sanofi; Takeda |
Research Funding - Alkermes (Inst); Astellas Pharma (Inst); Bristol-Myers Squibb (Inst); Checkmate Pharmaceuticals (Inst); Gan & Lee (Inst); GlaxoSmithKline (Inst); Glyconex (Inst); Immunocore (Inst); Intensity Therapeutics (Inst); Iovance Biotherapeutics (Inst); Kadmon (Inst); Kartos Therapeutics (Inst); Navire (Inst); Nektar (Inst); OncoSec (Inst); Regeneron (Inst); Seagen (Inst); Sound Biologics (Inst); Spring Bank (Inst); Sumitomo Group (Inst); Takeda (Inst); Targovax (Inst) |
(OPTIONAL) Uncompensated Relationships - Takeda |
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Consulting or Advisory Role - Amgen; BMS; Merck KGaA; MSD Oncology; Novartis; Philogen; Pierre fabre; Roche; Roche/Genentech; Sanofi; Sun Pharma |
Speakers' Bureau - Novartis |
Travel, Accommodations, Expenses - BMS; MSD Oncology; Novartis; Pierre Fabre |
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Consulting or Advisory Role - Bayer; Bristol-Myers Squibb; Genentech; Iovance Biotherapeutics; Macrogenics; Pfizer; Sanofi; Sun Biopharma |
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Consulting or Advisory Role - Eisai |
Speakers' Bureau - Bristol-Myers Squibb; Ipsen |
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Honoraria - Array BioPharma; Iovance Biotherapeutics |
Consulting or Advisory Role - Array BioPharma; Iovance Biotherapeutics; Merck; Nektar; Regeneron; Roche; Sanofi |
Research Funding - Alkermes (Inst); Amgen (Inst); Array BioPharma (Inst); Bristol-Myers Squibb (Inst); Incyte (Inst); Iovance Biotherapeutics (Inst); Kartos Therapeutics (Inst); Merck (Inst); Nektar (Inst); Neon Therapeutics (Inst); OncoSec (Inst); Regeneron (Inst); Replimune (Inst); Roche/Genentech (Inst); Seagen (Inst); Senhwa Biosciences (Inst); Ultimovacs (Inst) |
Travel, Accommodations, Expenses - Alkermes; Merck; Neon Therapeutics; Regeneron; Roche/Genentech |
(OPTIONAL) Uncompensated Relationships - Regeneron; Roche/Genentech |
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Consulting or Advisory Role - Elsevier; Hoosier Cancer Research Network; Via Oncology |
Research Funding - Bristol-Myers Squibb (Inst); Kartos Therapeutics (Inst); Pfizer/Array (Inst); Pfizer/EMD Serono (Inst) |
Other Relationship - Pfizer/Array |
(OPTIONAL) Uncompensated Relationships - American Association of Clinical Endocrinology; ASCO; NCCN |
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Consulting or Advisory Role - Castle Biosciences; Sanofi |
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Honoraria - Amgen; Bristol-Myers Squibb; Incyte; MSD; Novartis; Pfizer; Pierre Fabre; Roche |
Consulting or Advisory Role - Amgen; Bristol-Myers Squibb; Merck Serono; MSD; Novartis; Pierre Fabre; Roche; Sanofi |
Speakers' Bureau - Amgen; Bristol-Myers Squibb; MSD; Novartis; Roche |
Research Funding - Bristol-Myers Squibb (Inst); Roche (Inst) |
Travel, Accommodations, Expenses - Bristol-Myers Squibb; MSD; Novartis; Pierre Fabre; Sanofi |
Other Relationship - Avantis Medical Systems |
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Employment - Abbvie (I); Kartos Therapeutics; Sanofi; Telios |
Stock and Other Ownership Interests - Abbvie; GlaxoSmithKline |
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Employment - Kartos Therapeutics |
Stock and Other Ownership Interests - Kartos Therapeutics |
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No Relationships to Disclose |
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Leadership - Iovance Biotherapeutics |
Stock and Other Ownership Interests - Acerta Pharma/AstraZeneca (Inst); Kartos Therapeutics (Inst); Telios (Inst) |
Patents, Royalties, Other Intellectual Property - Telios Pharma and Kartos Therapeutics |
Travel, Accommodations, Expenses - Iovance Biotherapeutics; Kartos Therapeutics |
(OPTIONAL) Uncompensated Relationships - Kartos Therapeutics (Inst); Telios (Inst) |
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Honoraria - Bristol-Myers Squibb; Kura Oncology |
Consulting or Advisory Role - Bicara Therapeutics; Boxer Capital; Bristol-Myers Squibb; Exicure; General Catalyst; Kura Oncology; Merck; Naveris; Prelude Therapeutics; Rain Therapeutics; Remix Therapeutics; Sanofi |
Research Funding - Actuate Therapeutics (Inst); Bicara Therapeutics (Inst); Bristol-Myers Squibb (Inst); Conquer Cancer, the ASCO Foundation; Elevar Therapeutics (Inst); Exicure (Inst); Gateway for Cancer Research; Genzyme (Inst); GlaxoSmithKline (Inst); Kartos Therapeutics (Inst); Kite/Gilead (Inst); Kite/Gilead (Inst); NantKwest, (Inst); Regeneron (Inst); Secura Bio (Inst); V Foundation |
Expert Testimony - Aaronson Rappaport Feinstein & Deutsch; Ahmuty, Demers, & McManus; Wilson Elser Moskowitz Edelman & Dicker, LLP |
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Employment - Daichii Sankyo (I) |
Stock and Other Ownership Interests - daichii sankyo (I) |
Consulting or Advisory Role - ChemoCentryx; Exicure; Immunicum; Kartos Therapeutics |
Research Funding - AGIOS (Inst); Amgen (Inst); Exicure (Inst); INCYTE (Inst); Kartos Therapeutics (Inst); Merck (Inst); Servier (Inst); xencor (Inst) |