Ivosidenib in patients with IDH1-mutant relapsed/refractory myelodysplastic syndrome (R/R MDS): Updated enrollment and results of a phase 1 dose-escalation and expansion substudy.

David Andrew  Sallman

Consulting or Advisory Role - Abbvie; Bluebird Bio; Bristol-Myers Squibb; Gilead Sciences; Intellia Therapeutics; Janssen; Kite, a Gilead company; Magenta Therapeutics; Molecular Partners; Novartis; Servier; Shattuck Labs; Syndax; Syros Pharmaceuticals; Takeda

Speakers' Bureau - Bristol-Myers Squibb; Incyte; SERVIER

Research Funding - Aprea Therapeutics (Inst); Jazz Pharmaceuticals

James M.  Foran

Consulting or Advisory Role - Bristol-Myers Squibb/Celgene; Novartis; SERVIER; Syros Pharmaceuticals; Taiho Pharmaceutical

Research Funding - Abbvie (Inst); Actinium Pharmaceuticals (Inst); Aptose Biosciences (Inst); H3 Biomedicine (Inst); Kura Oncology (Inst); Sellas Life Sciences (Inst); Takeda (Inst); Trillium Therapeutics (Inst); Xencor (Inst)

Justin M.  Watts

Consulting or Advisory Role - Celgene; Jazz Pharmaceuticals; Pfizer

Speakers' Bureau - Jazz Pharmaceuticals

Research Funding - Takeda

Eytan  Stein

Stock and Other Ownership Interests  - Auron Therapeutics

Consulting or Advisory Role - Abbvie; Agios; Aptose Biosciences; Blueprint Medicines; Bristol-Myers Squibb/Celgene; Calithera Biosciences; CTI BioPharma Corp; Daiichi Sankyo; Debiopharm Group; Foghorn Therapeutics; GEMoaB; Genentech; Genesis Pharma; Gilead Sciences; Immunogen; Janssen; Jazz Pharmaceuticals; Jnana Therapeutics; Menarini; Neoleukin Therapeutics; Novartis; OnCusp Therapeutics; Ono Pharmaceutical; Pinotbio; SERVIER; Syndax

Research Funding - agios (Inst); Bayer (Inst); BioTheryX (Inst); Bristol-Myers Squibb/Celgene (Inst); Cleave Biosciences (Inst); Eisai (Inst); Foghorn Therapeutics (Inst); Gilead Sciences (Inst); Loxo/Lilly (Inst); Prelude Therapeutics (Inst); SERVIER (Inst); Syndax (Inst); Syros Pharmaceuticals (Inst)

Stéphane  De Botton

Honoraria - Abbvie; Astellas Pharma; Bristol-Myers Squibb; Jazz Pharmaceuticals; SERVIER

Consulting or Advisory Role - Bristol-Myers Squibb; GlaxoSmithKline; SERVIER; Syndax

Speakers' Bureau - Abbvie; Astellas Pharma; Bristol-Myers Squibb; Jazz Pharmaceuticals; SERVIER

Research Funding - Auron Therapeutics; Forma Therapeutics

Travel, Accommodations, Expenses - Abbvie; SERVIER

Amir Tahmasb  Fathi

Consulting or Advisory Role - Abbvie; Agios; Amgen; Astellas Pharma; Blueprint Medicines; Bristol-Myers Squibb; Bristol-Myers Squibb; Daiichi Sankyo; Foghorn Therapeutics; Forty Seven; Genentech; Ipsen; Kite, a Gilead company; Kura Oncology; MorphoSys; MorphoSys; Novartis; Pfizer; Seagen; Takeda; Trillium Therapeutics; Trovagene

Research Funding - Abbvie (Inst); agios (Inst); Bristol-Myers Squibb (Inst); SERVIER (Inst); Takeda (Inst)

Gabrielle T.  Prince

No Relationships to Disclose

Richard M.  Stone

Honoraria - DAVA Pharmaceuticals; Medscape; Prime Oncology; Research to Practice

Consulting or Advisory Role - Abbvie; Actinium Pharmaceuticals; Agios; Amgen; Aprea Therapeutics; Arog; Astellas Pharma; BerGenBio; Biolinerx; Boston Pharmaceuticals; Bristol Myers Squibb; Celgene; CTI BioPharma Corp; Daiichi-Sankyo; ElevateBio; Foghorn Therapeutics; Gemoab; GlaxoSmithKline; Innate Pharma; Janssen; Jazz Pharmaceuticals; Macrogenics; Novartis; Onconova Therapeutics; Syndax; Syntrix Biosystems; Syros Pharmaceuticals; Takeda; Trovagene

Research Funding - Abbvie/Genentech (Inst); Agios (Inst); Novartis (Inst)

Prapti Arvind  Patel

Honoraria - Jazz Pharmaceuticals; OncLive

Consulting or Advisory Role - Agios; Bristol-Myers Squibb/Celgene; SERVIER

Gail J.  Roboz

Consulting or Advisory Role - Abbvie; Actinium Pharmaceuticals; Agios; Amgen; Astellas Pharma; Astex Pharmaceuticals; Bayer; Bayer; Bristol-Myers Squibb; Celgene; Celltrion; Daiichi Sankyo; Genentech/Roche; GlaxoSmithKline; Helsinn Therapeutics; Janssen; Jasper Therapeutics; Jazz Pharmaceuticals; MedImmune; MEI Pharma; Mesoblast; Novartis; Otsuka; Pfizer; Roche; Sandoz; Takeda

Research Funding - Abbvie (Inst); Agios (Inst); amphivena (Inst); Astex Pharmaceuticals (Inst); Celgene (Inst); Cellectis (Inst); Cellectis (Inst); CTI (Inst); Janssen (Inst); Karyopharm Therapeutics (Inst); MedImmune (Inst); MEI Pharma (Inst); Moffitt (Inst); Novartis (Inst); Onconova Therapeutics (Inst); Pfizer (Inst); Sunesis Pharmaceuticals (Inst); Tensha Therapeutics (Inst)

Travel, Accommodations, Expenses - Abbvie; Agios; Amgen; Amphivena; Array BioPharma; Astex Pharmaceuticals; Bayer; Celgene; Celltrion; Clovis Oncology; Eisai; Janssen; Jazz Pharmaceuticals; Novartis; Pfizer; Roche/Genentech; Sandoz; Sunesis Pharmaceuticals

Martha Lucia  Arellano

Consulting or Advisory Role - Kite, a Gilead company; Syndax

Harry Paul  Erba

Consulting or Advisory Role - Abbvie/Genentech; Agios; Amgen; Astellas Pharma; Celgene; Daiichi Sankyo; Glycomimetics; Immunogen; Incyte; Janssen Oncology; Jazz Pharmaceuticals; Kura Oncology; Macrogenics; Novartis; Pfizer; Takeda; Trillium Therapeutics

Speakers' Bureau - Abbvie/Genentech; Agios; Celgene; Incyte; Jazz Pharmaceuticals; Novartis

Research Funding - Abbvie; Abbvie (Inst); Agios (Inst); ALX Oncology (Inst); Amgen (Inst); Daiichi Sankyo (Inst); FORMA Therapeutics (Inst); Gilead/Forty Seven (Inst); Glycomimetics (Inst); Immunogen (Inst); Jazz Pharmaceuticals (Inst); Macrogenics (Inst); Novartis (Inst); PTC Therapeutics (Inst)

Other Relationship - Celgene; Glycomimetics

(OPTIONAL) Uncompensated Relationships - Daiichi Sankyo

Arnaud  Pigneux

Honoraria - Astellas Pharma

Research Funding - Abbvie; Astellas Pharma

Praneeth  Baratam

Honoraria - Celgene/Bristol-Myers Squibb

Consulting or Advisory Role - Celgene/Bristol-Myers Squibb

Xavier G.  Thomas

No Relationships to Disclose

Xiaofei  Bai

No Relationships to Disclose

Stephanie M.  Kapsalis

Employment - SERVIER

Guillermo  Garcia-Manero

Honoraria - Abbvie; Acceleron Pharma; Astex Pharmaceuticals; Bristol-Myers Squibb/Celgene; Curis; Genentech; Gilead Sciences; Novartis

Consulting or Advisory Role - Acceleron Pharma; Astex Pharmaceuticals; Bristol-Myers Squibb

Research Funding - Abbvie; Aprea Therapeutics; Astex Pharmaceuticals; Bristol-Myers Squibb; Curis; Genentech; Gilead Sciences; Novartis

Courtney Denton  Dinardo

Leadership - Notable Labs

Stock and Other Ownership Interests  - Notable Labs

Honoraria - Abbvie; Agios; Bluebird Bio; Celgene; Foghorn Therapeutics; Genentech/Abbvie; Genmab; GlaxoSmithKline; Jazz Pharmaceuticals; Novartis; SERVIER; Takeda

Consulting or Advisory Role - Abbvie; Agios; Celgene; GlaxoSmithKline

Research Funding - Abbvie; AGIOS; Celgene; Cleave Therapeutics; Daiichi Sankyo; Foghorn Therapeutics; Immune-Onc Therapeutics; Jazz Pharmaceuticals