The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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Pharmacokinetic and pharmacodynamic activity evaluation of MAK683, a selective oral embryonic ectoderm development (EED) inhibitor, in adults with advanced malignancies in a first-in-human study.
 
Vincent Ribrag
Honoraria - Abbvie; AZD; Gilead Sciences; Infinity Pharmaceuticals; NanoString Technologies; Novartis; roche
Consulting or Advisory Role - Bristol-Myers Squibb; Gilead Sciences; Immune Design; Incyte; Infinity Pharmaceuticals; MSD; NanoString Technologies; PharmaMar; Roche; Roche/Genentech
Research Funding - arGEN-X BVBA; argenx (Inst); Astex Pharmaceuticals (Inst); Epizyme (Inst); GlaxoSmithKline/Adaptimmune (Inst)
Expert Testimony - SERVIER
Travel, Accommodations, Expenses - azd; AZD; Bristol-Myers Squibb; Bristol-Myers Squibb; Roche
 
Zev A. Wainberg
Consulting or Advisory Role - Amgen; Arcus Biosciences; AstraZeneca/MedImmune; Bayer; Bristol-Myers Squibb; Daiichi Sankyo/Astra Zeneca; Five Prime Therapeutics; Ipsen; Lilly; Macrogenics; Merck; Merck KGaA; Novartis; Pfizer; PureTech; QED Therapeutics
Research Funding - Five Prime Therapeutics (Inst); Merck (Inst); Novartis (Inst); Pfizer (Inst); Plexxikon (Inst)
Travel, Accommodations, Expenses - Bayer; Lilly; Merck
 
Lara Iglesias Docampo
Consulting or Advisory Role - Bayer; Lilly; Merck; MSD; Roche; Sanofi
Speakers' Bureau - Bayer; Eisai; Kyowa Kirin; MSD; Roche
 
Thiruvamoor Ramkumar
Employment - Novartis
Stock and Other Ownership Interests - Novartis
 
Louise Barys
Employment - Novartis
Stock and Other Ownership Interests - Novartis
 
Shuqi Chen
Employment - Novartis
 
Marc Raccuglia
Employment - Novartis
Stock and Other Ownership Interests - Novartis
Honoraria - Novartis
 
Mélanie Wilbaux
Employment - Novartis
 
Karen Beltz
Employment - Novartis Institutes for BioMedical Research
 
Amy Luyt
Employment - Novartis
 
Yu Yun Fan
Employment - Novartis
 
Naoko Suenaga
Employment - Novartis
 
Fangjun Luo
Employment - Novartis
 
Xuan Dai
Employment - Novartis
 
Clinton Lai
Employment - Novartis
Stock and Other Ownership Interests - Novartis
 
Jia Chen
Employment - Novartis