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NHS-Galleri Trial Design: Equitable study recruitment tactics for targeted population-level screening with a multi-cancer early detection (MCED) test. |
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Stock and Other Ownership Interests - Achilles Therapeutics; Apogen Biotechnologies; Epic Sciences; GRAIL |
Honoraria - Amgen; AstraZeneca; Boehringer Ingelheim; Bristol-Myers Squibb; Celgene; GlaxoSmithKline; Illumina; Lilly; MSD Oncology; Novartis; Ono Pharmaceutical; Pfizer; Roche |
Consulting or Advisory Role - Bicycle Therapeutics; Genentech/Roche; GRAIL; Medicxi; Metabomed; Roche; Sarah Cannon Research Institute |
Research Funding - Archer; AstraZeneca; BMS; Boehringer Ingelheim; Ono Pharmaceutical; Pfizer; Roche |
Patents, Royalties, Other Intellectual Property - Founder of Achilles Therapeutics: a biotechnology company funded by Syncona/Wellcome Trust to target clonal Neoantigens through vaccine and cell therapy approaches; Immune checkpoint intervention in cancer (PCT/EP2016/071471),; Method for determining whether an HLA allele is lost in a tumour (PCT/GB2018/052004); Method for identifying responders to cancer treatment (PCT/GB2018/)051912); Method for treating cancer (PCT/EP2016/059401).; Method for treating cancer based on identification of clonal neo-antigens (PCT/EP2016/059401); Method of detecting tumour recurrence (PCT/GB2017/053289); Method of identifying insertion/deletion mutation targets (PCT/GB2018/051892); Method of predicting survival rates for cancer patients (PCT/GB2020/050221); Method of treating cancer by targeting insertion/deletion mutations (PCT/GB2018/051893); Methods for lung cancer detection (PCT/US2017/028013) |
(OPTIONAL) Uncompensated Relationships - AstraZeneca (Inst) |
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Consulting or Advisory Role - GRAIL; GRAIL (Inst) |
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Honoraria - Epizyme; Genmab; InCyte |
Consulting or Advisory Role - Epizyme |
Patents, Royalties, Other Intellectual Property - Combined use of Fc gamma RIIb (CD32b) and CD20 - specific antibodies. WO Patent, PCT/GB2011/051572; EU11760819.0 |
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Stock and Other Ownership Interests - GRAIL; Illumina |
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Employment - GRAIL; GRAIL |
Stock and Other Ownership Interests - GRAIL; GRAIL |
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Stock and Other Ownership Interests - GRAIL |
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No Relationships to Disclose |
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Consulting or Advisory Role - GRAIL; Roche Molecular Diagnostics |
Research Funding - GRAIL (Inst) |
Expert Testimony - Dr. Reddy's Laboratories; Mylan; Sandoz; Teva |