The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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First-in-human phase 1/2 study of autologous T cells engineered using the Sleeping Beauty System transposon/transposase to express T-cell receptors (TCRs) reactive against cancer-specific mutations in patients with advanced solid tumors.
 
Marcelo Vailati Negrao
Consulting or Advisory Role - Merck; Mirati Therapeutics
Research Funding - Alaunos Therapeutics; AstraZeneca; Checkmate Pharmaceuticals; Genentech; Mirati Therapeutics; Novartis; Pfizer; ZIOPHARM Oncology
Other Relationship - Apothecom; Ashfield Healthcare; ZIOPHARM Oncology
 
Maria Pia Morelli
No Relationships to Disclose
 
Amir A. Jazaeri
Stock and Other Ownership Interests - Avenge Bio
Honoraria - Gerson Lehrman Group; Guidepoint Global; Mosaic Research Management
Consulting or Advisory Role - Agenus; Bristol-Myers Squibb; Genentech/Roche; GlaxoSmithKline; integrity Continuing Education; Iovance Biotherapeutics; Macrogenics; NuProbe; twoXAR
Research Funding - AstraZeneca (Inst); Bristol-Myers Squibb (Inst); immatics (Inst); Iovance Biotherapeutics (Inst); Lilly (Inst); Merck (Inst); Pfizer (Inst); ZIOPHARM Oncology (Inst)
 
Benny Johnson
Consulting or Advisory Role - Gritstone Bio; Incyte; Insmed; Taiho Oncology
Research Funding - Bristol-Myers Squibb (Inst); Syntrix Biosystems (Inst)
 
Partow Kebriaei
Honoraria - Kite, a Gilead company; Novartis; Pfizer
Consulting or Advisory Role - Jazz Pharmaceuticals
Research Funding - Amgen; ZIOPHARM Oncology
Travel, Accommodations, Expenses - Kite, a Gilead company; Novartis; Pfizer
 
Drew Deninger
Employment - Alaunos Therapeutics
Leadership - Alaunos Therapeutics
Stock and Other Ownership Interests - Alaunos Therapeutics
Research Funding - Alaunos Therapeutics
Patents, Royalties, Other Intellectual Property - National Cancer Institute
Travel, Accommodations, Expenses - Alaunos Therapeutics
 
Eleanor De Groot
Employment - Alaunos Therapeutics
Leadership - Alaunos Therapeutics
Stock and Other Ownership Interests - Alaunos Therapeutics; WuXi Biologics
Consulting or Advisory Role - Bioasis Technologies (I); DelMar Pharmaceuticals (I); GenomiCare (I); GlaxoSmithKline (I); Inc Research (I); InSightec (I); Janssen (I); Karyopharm Therapeutics (I); KIYATEC (I); Magnolia Innovation (I); Merck (I); Merck Sharp & Dohme (I); Monteris Medical (I); Mundipharma Research (I); Novartis (I); Prelude Therapeutics (I); resTORbio (I); Roche (I); Samus Therapeutics (I); Sapience Therapeutics (I); Sumitomo Dainippon Pharma Oncology (I)
Research Funding - CarThera (I); Haihe Biopharma (I); Taiho Pharmaceutical (I)
Other Relationship - Cure Brain Cancer Foundation (I); Seaver Autism Center; VBI Vaccines (I)
 
Matthew R. Collinson-Pautz
Employment - Alaunos Therapeutics; Bellicum Pharmaceuticals
Stock and Other Ownership Interests - Alaunos Therapeutics; Bellicum Pharmaceuticals
Research Funding - Alaunos Therapeutics; Bellicum Pharmaceuticals
Patents, Royalties, Other Intellectual Property - Alaunos Therapeutics; Bellicum Pharmaceuticals
Travel, Accommodations, Expenses - Alaunos Therapeutics; Bellicum Pharmaceuticals
 
Nathan A. Demars
Employment - Alaunos Therapeutics
Stock and Other Ownership Interests - Abbvie; Alaunos Therapeutics; Verastem
 
Jaymes S. Holland
Employment - Alaunos Therapeutics
 
John Heymach
Stock and Other Ownership Interests - Bio-Tree; Cardinal Spine
Consulting or Advisory Role - AstraZeneca; Boehringer Ingelheim; BrightPath Biotheraputics; Bristol-Myers Squibb; Catalyst Biotech; EMD Serono; Foundation medicine; Genentech/Roche; GlaxoSmithKline; Guardant Health; Hengrui Pharmaceutical; Janssen; Kairos Ventures; Leads Biolabs; Lilly; Mirati Therapeutics; Nexus Health Systems; Novartis; Pneuma Respiratory; Roche; Sanofi/Aventis; Spectrum Pharmaceuticals; Takeda
Research Funding - AstraZeneca (Inst); GlaxoSmithKline; Spectrum Pharmaceuticals
Patents, Royalties, Other Intellectual Property - Licensing agreement between Spectrum and MD Anderson (including myself) regarding intellectual property for treatment of EGFR and HER2 exon 20 mutations
 
Raffaele Baffa
Employment - Alaunos Therapeutics
Leadership - Alaunos Therapeutics
Stock and Other Ownership Interests - Alaunos Therapeutics
Travel, Accommodations, Expenses - Alaunos Therapeutics
 
Scott Kopetz
Stock and Other Ownership Interests - Frontier Medicines; Iylon; Lutris; MolecularMatch
Consulting or Advisory Role - Abbvie; Amal Therapeutics; AstraZeneca/MedImmune; Bayer Health; Bicara Therapeutics; Boehringer Ingelheim; Boston Biomedical; Carina Biotech; Daiichi Sankyo; EMD Serono; EMD Serono; Endeavor BioMedicines; Flame Biosciences; Frontier Medicines; Genentech; Genomic Health; Gilead Sciences; GlaxoSmithKline; HalioDx; Holy Stone Healthcare; Inivata; Ipsen; Iylon; Jacobio; Jazz Pharmaceuticals; Johnson & Johnson/Janssen; Lilly; Lutris; Merck; Mirati Therapeutics; Natera; Novartis; Numab; Pfizer; Pierre Fabre; Redx Pharma; Repare Therapeutics; Replimune; Servier; Taiho Pharmaceutical; Xilis
Research Funding - Amgen; Array BioPharma; Biocartis; Daiichi Sankyo; EMD Serono; Genentech/Roche; Guardant Health; Lilly; MedImmune; Novartis; Sanofi