The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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ATTAC-MCC: Phase I/II study of autologous CD8+ and CD4+ transgenic T cells expressing a high affinity MCPyV-specific TCR combined with checkpoint inhibitors and class I MHC-upregulation in patients with metastatic MCC refractory to PD-1 axis blockade.

Joshua  Veatch

Stock and Other Ownership Interests  - Lyell Immunopharma

Research Funding - Lyell Immunopharma

Patents, Royalties, Other Intellectual Property - Lyell Immunopharma

Ananth  Akkiraju

Employment - Affini-T Therapeutics

Stock and Other Ownership Interests  - Affini-T Therapeutics

Travel, Accommodations, Expenses - Mirati Therapeutics

Agus  Darwanto

Employment - Affini-T Therapeutics

Stock and Other Ownership Interests  - Affini-T Therapeutics

Sean  Garrity

Employment - Affini-T Therapeutics; Moderna Therapeutics (I); Takeda

Stock and Other Ownership Interests  - Affini-T Therapeutics; Bluebird Bio; Moderna Therapeutics (I); Takeda

Damien  Hallet

Employment - Affini-T Therapeutics

Stock and Other Ownership Interests  - Affini-T Therapeutics

Consulting or Advisory Role - Affini-T Therapeutics

Patents, Royalties, Other Intellectual Property - Heat Biologics

Travel, Accommodations, Expenses - Affini-T Therapeutics; Precision BioSciences; TFS

Kim  Nguyen

Employment - Affini-T Therapeutics; Precision BioSciences

Leadership - Affini-T Therapeutics

Stock and Other Ownership Interests  - Affini-T Therapeutics; Precision BioSciences

Research Funding - Affini-T Therapeutics; Precision BioSciences

Patents, Royalties, Other Intellectual Property - Terumo BCT, Inc.

Piotr  Pierog

Employment - Affini-T Therapeutics; Takeda

Stock and Other Ownership Interests  - Affini-T Therapeutics; Atara Biotherapeutics; GlaxoSmithKline; Immatics; Instil Bio; Iovance Biotherapeutics; Novartis; Pfizer; Sana Biotechnology; Takeda; Unity Biotechnology

Tomasz  Sewastianik

Employment - Affini-T Therapeutics; Double Rainbow Biosciences (I)

Stock and Other Ownership Interests  - Affini-T Therapeutics; Double Rainbow Biosciences (I)

Patents, Royalties, Other Intellectual Property - Dana-Farber Cancer Institute

Markus P  Vallaster

Employment - Affini-T Therapeutics; AstraZeneca/MedImmune

Stock and Other Ownership Interests  - Affini-T Therapeutics

Loic  Vincent

Employment - Affini-T Therapeutics

Stock and Other Ownership Interests  - Affini-T Therapeutics

Aude  Chapuis

Stock and Other Ownership Interests  - Affini-T Therapeutics; Metagenomi; SignalOne Bio; TScan Therapeutics

Honoraria - Affini-T Therapeutics; SignalOne Bio; TScan Therapeutics

Consulting or Advisory Role - Affini-T Therapeutics

Research Funding - Affini-T Therapeutics; Amazon; Lonza; SignalOne Bio