The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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A multicenter, open-label, phase 1a/b study of HC-7366, a modulator of integrated stress response (ISR) kinase GCN2 in subjects with advanced solid tumors.
 
Meredith Pelster
Honoraria - Castle Biosciences (I)
Consulting or Advisory Role - Bayer (Inst); Novartis (Inst)
Research Funding - CytomX Therapeutics (Inst); HiberCell (Inst); SQZ Biotechnology (Inst); Surface Oncology (Inst); ZielBio (Inst)
 
Marcio Torre
Employment - Aeon Therapeutics
Leadership - Aeon Therapeutics
Stock and Other Ownership Interests - Abbvie; Aeon Therapeutics; Amgen; Biomarin
Consulting or Advisory Role - Castle IRB; Catalyst Biotech; InClin; Janssen
Research Funding - Aeon Therapeutics
Travel, Accommodations, Expenses - Aeon Therapeutics
Other Relationship - IQVIA; Roche
 
Geoffrey Sumithran Kannan
Employment - LabCorp
Stock and Other Ownership Interests - LabCorp
 
Michele Anne Gargano
Employment - HiberCell
Stock and Other Ownership Interests - Biothera; HiberCell
 
Paulette Mattson
Employment - HiberCell
Stock and Other Ownership Interests - Biothera; HiberCell
 
Blaine Rathmann
Employment - HiberCell
Stock and Other Ownership Interests - HiberCell
 
Nandita Bose
Employment - HiberCell
Patents, Royalties, Other Intellectual Property - HiberCell
 
Jose Luis Iglesias
Consulting or Advisory Role - Carina; Epsilogen; HiberCell; Panavance Therapeutics; Senti Biosciences