The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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TTI-622-01: A phase 1a/1b dose-escalation and expansion trial of TTI-622 in patients with advanced hematologic malignancies, including multiple myeloma.
 
Krish Patel
Consulting or Advisory Role - Abbvie; ADC Therapeutics; AstraZeneca; BeiGene; Bristol-Myers Squibb/Celgene/Juno; Epizyme; Genentech; Kite, a Gilead company; Loxo/Lilly; Morphosys; Pharmacyclics; Seagen; TG Therapeutics
Speakers' Bureau - AstraZeneca; Bristol-Myers Squibb/Celgene; Kite, a Gilead company; TG Therapeutics
Research Funding - Aptevo Therapeutics (Inst); AstraZeneca (Inst); Bristol-Myers Squibb (Inst); Celgene (Inst); Curis (Inst); Epizyme (Inst); Fate Therapeutics (Inst); Kite/Gilead (Inst); Loxo/Lilly (Inst); MEI Pharma (Inst); Nurix (Inst); Pharmacyclics (Inst); Roche/Genentech (Inst); Takeda (Inst); Trillium Therapeutics (Inst); Xencor (Inst)
 
Robert Z. Orlowski
Stock and Other Ownership Interests - Asymmetric Therapeutics
Consulting or Advisory Role - Amgen; AstraZeneca Canada; Bristol-Myers Squibb; Celgene; EcoR1 Capital; GlaxoSmithKline; Ionis Pharmaceuticals; Janssen; Kite, a Gilead Company; Legend Biotech; Molecular Partners; Regeneron; Sanofi; Takeda
Research Funding - BioTheryX
 
Kimberley Doucette
Honoraria - Sanofi
 
Michael Maris
Consulting or Advisory Role - Pfizer; Trillium Therapeutics
 
Matthew James Pianko
Consulting or Advisory Role - GlaxoSmithKline; Janssen Oncology; Karyopharm Therapeutics; Oncopeptides; Sanofi; Trillium Therapeutics
Research Funding - Nektar (Inst); Pfizer (Inst); Regeneron (Inst); Trillium Therapeutics (Inst)
 
Radhakrishnan Ramchandren
Consulting or Advisory Role - Bristol-Myers Squibb; Pharmacyclics/Janssen; Sandoz-Novartis; Seagen
Research Funding - Genentech; Janssen; Merck; Seagen
 
Don A. Stevens
No Relationships to Disclose
 
David H. Vesole
Stock and Other Ownership Interests - Abbvie; Amgen; Biogen; Bristol-Myers Squibb; Gilead Sciences; Johnson & Johnson; Lilly; Merck; Novartis; Sorrento Therapeutics
Speakers' Bureau - Amgen; Bristol-Myers Squibb; GlaxoSmithKline; Janssen Oncology; Sanofi; Takeda
 
Robert A. Uger
Employment - Pfizer; Trillium Therapeutics
 
Anita Scheuber
Employment - Pfizer; Trillium Therapeutics
 
Naomi Molloy
Employment - Pfizer; Trillium Therapeutics
 
Ingmar Bruns
Employment - Pfizer; Trillium Therapeutics
 
Alexander M. Lesokhin
Honoraria - ITeos Therapeutics; Janssen; Legend Biotech; Pfizer; Sanofi; Trillium Therapeutics
Consulting or Advisory Role - Pfizer; Trillium Therapeutics
Research Funding - Bristol-Myers Squibb (Inst); Genentech (Inst); Janssen Oncology (Inst); Pfizer (Inst); Sanofi (Inst); Trillium Therapeutics (Inst)
Patents, Royalties, Other Intellectual Property - Serametrix, Inc