The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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First clinical and immunogenicity results including all subjects enrolled in a phase I study of Nous-209, an off-the-shelf immunotherapy, with pembrolizumab, for the treatment of tumors with a deficiency in mismatch repair/microsatellite instability (dMMR/MSI).
 
Marwan Fakih
Honoraria - Amgen
Consulting or Advisory Role - Amgen; Array BioPharma; Bayer; GlaxoSmithKline; Incyte; Pfizer; Seagen; Taiho Pharmaceutical; Zhuhai DL Biotech
Speakers' Bureau - Guardant Health
Research Funding - Amgen (Inst); AstraZeneca (Inst); Novartis (Inst)
 
Dung T. Le
Stock and Other Ownership Interests - Seagen
Honoraria - Merck
Consulting or Advisory Role - Bristol-Myers Squibb; HalioDX; Janssen; Merck; Nouscom
Research Funding - Abbvie (Inst); Aduro Biotech; Bristol-Myers Squibb; Curegenix; Medivir; Merck; Nouscom (Inst)
Patents, Royalties, Other Intellectual Property - Inventor of technology, "Microsatellite Instability as a Pharmacogenomic Marker of Therapeutic Response to Immune Checkpoint Inhibition".
 
Katrina Sophia Pedersen
Consulting or Advisory Role - Array BioPharma; Bayer; Novartis; Pfizer
Speakers' Bureau - Clinical Care Options; WebMD
Research Funding - Abbvie (Inst); Arcus Biosciences (Inst); Boston Biomedical (Inst); Bristol-Myers Squibb (Inst); Daiichi Sankyo/Lilly (Inst); Ipsen (Inst); Merck (Inst); Natera (Inst); Nouscom (Inst); Novartis (Inst); Pfizer (Inst); Rafael Pharmaceuticals (Inst); Roche/Genentech (Inst)
Travel, Accommodations, Expenses - Array BioPharma; BeiGene; Nouscom
Other Relationship - UpToDate
(OPTIONAL) Uncompensated Relationships - NCCN
 
Anthony Frank Shields
Consulting or Advisory Role - Caris Life Sciences; ImaginAb
Speakers' Bureau - Caris Life Sciences
Research Funding - Alkermes; Astellas Pharma; AstraZeneca; Bayer; Boehringer Ingelheim; Boston Biomedical; Caris Life Sciences; Daiichi Sankyo; Eisai; Esperas Pharma; Esperas Pharma; Exelixis; Five Prime Therapeutics; H3 Biomedicine; Halozyme; Hutchison China Meditech; ImaginAb; Incyte; Inovio Pharmaceuticals; Jiangsu Alphamab Biopharmaceuticals; Lexicon; LSK BioPharma; MSK Pharma; Nouscom; Plexxikon; Repertoire Immune Medicines; Seagen; Shanghai HaiHe Pharmaceutical; Taiho Pharmaceutical; Telix Pharmaceuticals; TopAlliance BioSciences Inc (Inst); Xencor
Travel, Accommodations, Expenses - Caris Life Sciences; GE Healthcare; ImaginAb; Inovio Pharmaceuticals; TransTarget
 
Manish A. Shah
Research Funding - Bristol-Myers Squibb (Inst); Merck (Inst); Oncolys BioPharma (Inst)
 
Sarbajit Mukherjee
Research Funding - Ipsen (Inst)
Travel, Accommodations, Expenses - Nouscom (Inst)
 
Patricia Delaite
Employment - Nouscom
Leadership - Nouscom
Stock and Other Ownership Interests - Nouscom
Patents, Royalties, Other Intellectual Property - Nouscom (Inst)
 
Théa Faivre
Employment - Nouscom
Stock and Other Ownership Interests - Nouscom
Patents, Royalties, Other Intellectual Property - Nouscom (Inst)
 
Anna Morena D'Alise
Employment - Nouscom
Stock and Other Ownership Interests - Nouscom
Patents, Royalties, Other Intellectual Property - Nouscom
 
Guido Leoni
Employment - Nouscom
Stock and Other Ownership Interests - Nouscom
Patents, Royalties, Other Intellectual Property - Nouscom
 
Gabriella Cotugno
Employment - Nouscom
Stock and Other Ownership Interests - Nouscom
Patents, Royalties, Other Intellectual Property - Nouscom
 
Francesca Langone
Employment - Nouscom
Patents, Royalties, Other Intellectual Property - Nouscom (Inst)
 
Elisa Scarselli
Employment - Nouscom
Leadership - Nouscom
Stock and Other Ownership Interests - Nouscom
Patents, Royalties, Other Intellectual Property - Nouscom
 
Michael J. Overman
Consulting or Advisory Role - 3D Medicines; Array BioPharma; Bristol-Myers Squibb; Gritstone Bio; Janssen; Janssen; MedImmune; Merck; Novartis; Pfizer; Pfizer; Promega; Roche/Genentech; Spectrum Pharmaceuticals
Research Funding - Bristol-Myers Squibb; MedImmune; Merck; Roche