The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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Defining resistance mechanisms to CDK4/6 inhibition in hormone receptor-positive HER2-negative metastatic breast cancer (MBC) through a machine learning approach applied to circulating tumor DNA (ctDNA).
 
Lorenzo Gerratana
Consulting or Advisory Role - Lilly; Novartis
 
Carolina Reduzzi
Research Funding - Menarini Silicon Biosystems
 
Andrew A. Davis
No Relationships to Disclose
 
Marko Velimirovic
Stock and Other Ownership Interests - Abbvie; Amgen
 
Katherine Clifton
No Relationships to Disclose
 
Whitney L Hensing
No Relationships to Disclose
 
Ami N. Shah
Consulting or Advisory Role - AstraZeneca/MedImmune
 
Charles Sichao Dai
No Relationships to Disclose
 
Paolo D’Amico
Research Funding - Roche Italy (Inst)
 
Jeannine Donahue
No Relationships to Disclose
 
Qiang Zhang
No Relationships to Disclose
 
Alexandro Membrino
No Relationships to Disclose
 
Firas Hazem Wehbe
No Relationships to Disclose
 
Arielle Janine Medford
No Relationships to Disclose
 
William John Gradishar
Consulting or Advisory Role - AstraZeneca; BeyondSpring Pharmaceuticals; Genentech/Roche; merck; Pfizer; Puma Biotechnology; Seagen
 
Amir Behdad
Honoraria - Bayer; Lilly; Roche China; Thermo Fisher Scientific
Speakers' Bureau - Bayer; Lilly; Roche China; Thermofisher Scientific Biomarkers
Travel, Accommodations, Expenses - Bayer; Foundation Medicine; Pfizer
 
Cynthia X. Ma
Consulting or Advisory Role - Agendia; AstraZeneca; Athenex; Bayer; Biovica; Eisai; Gilead Sciences; Inivata; Jacobio; Natera; Novartis; Olaris; Philips Electronics; Puma Biotechnology; Sanofi; Seagen
Research Funding - Pfizer (Inst); Puma Biotechnology (Inst)
 
Seth Andrew Wander
Consulting or Advisory Role - Biovica; Foundation Medicine; Hologic; Lilly; Pfizer; Puma Biotechnology; Veracyte
Research Funding - Genentech
 
Fabio Puglisi
Honoraria - Daiichi Sankyo; Novartis; Pfizer; Roche
Consulting or Advisory Role - Lilly; Novartis; Pfizer
 
Massimo Cristofanilli
Honoraria - Foundation Medicine; Pfizer
Consulting or Advisory Role - AstraZeneca/Daiichi Sankyo; Ellipses Pharma; Foundation Medicine; Lilly; Menarini; Olaris
Research Funding - Angle; Lilly; Merck