The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
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Single agent PD-1 blockade as curative-intent treatment in mismatch repair deficient locally advanced rectal cancer.
Andrea Cercek
Consulting or Advisory Role - Bayer; GlaxoSmithKline; Incyte; Janssen; Merck; Seagen
Research Funding - GlaxoSmithKline; Rgenix (Inst); Seagen
Melissa Amy Lumish
No Relationships to Disclose
Jenna Cohen Sinopoli
No Relationships to Disclose
Jill A. Weiss
No Relationships to Disclose
Jinru Shia
Consulting or Advisory Role - PAIGE.AI
Zsofia Kinga Stadler
Consulting or Advisory Role - Adverum (I); Alcon (I); Gyroscope (I); Neurogene (I); Regenxbio (I)
Rona Yaeger
Consulting or Advisory Role - Array BioPharma; Mirati Therapeutics; Natera
Research Funding - Array BioPharma (Inst); Boehringer Ingelheim (Inst); Mirati Therapeutics (Inst); Pfizer (Inst)
Jesse Joshua Smith
Consulting or Advisory Role - Foundation Medicine; Guardant Health
Leonard B. Saltz
Consulting or Advisory Role - Genor BioPharma
Research Funding - Taiho Pharmaceutical
Imane H. El Dika
Honoraria - Lynx Group
Consulting or Advisory Role - QED Therapeutics
Travel, Accommodations, Expenses - QED Therapeutics
Christopher H. Crane
Stock and Other Ownership Interests - Oncternal Therapeutics
Honoraria - Elekta
Consulting or Advisory Role - TriSalus Life Sciences
Research Funding - Elekta (Inst)
Paul Bernard Romesser
Stock and Other Ownership Interests - Pfizer
Consulting or Advisory Role - EMD Serono
Research Funding - EMD Serono
Travel, Accommodations, Expenses - Elekta
Kirshna Iyer
No Relationships to Disclose
Philip Paty
No Relationships to Disclose
Julio Garcia-Aguilar
Stock and Other Ownership Interests - Intuitive surgical
Consulting or Advisory Role - Intuitive Surgical; Johnson & Johnson; Medtronic
Mithat Gonen
Travel, Accommodations, Expenses - Genentech
Marc J Gollub
Stock and Other Ownership Interests - Pfizer
Martin R. Weiser
Consulting or Advisory Role - Precisca
Research Funding - Clinical Genomics
Patents, Royalties, Other Intellectual Property - UpToDate Section Editor
Kurt A. Schalper
Consulting or Advisory Role - Agenus; Clinica Alemana; Dynamo Therapeutics; EMD Serono; Excite International; Merck; Ono Pharmaceutical; Pierre Fabre; Shattuck Labs; Takeda; Torque
Speakers' Bureau - Bristol-Myers Squibb; BTIG; Fluidigm; Genmab; Merck; Peerview; Takeda
Research Funding - AstraZeneca; Bristol-Myers Squibb; Lilly; Merck; Moderna Therapeutics; Navigate BioPharma; Pierre Fabre; Ribon Therapeutics; Surface Oncology; Takeda; Tesaro
Patents, Royalties, Other Intellectual Property - Patent No. 16/464,010 (PREDICTION OF RESPONSE TO IMMUNE-MODULATORY THERAPIES)
Luis A. Diaz
Leadership - Jounce Therapeutics; Personal Genome Diagnostics
Stock and Other Ownership Interests - Amgen (I); Delfi Diagnostics; Four Paws; Jounce Therapeutics; Kinnate Biopharma; Neophore; Personal Genome Diagnostics; Seer; Thrive Earlier Detection Corp; Zydecom
Consulting or Advisory Role - Four Paws; Innovatus Capital Partners; Kinnate Biopharma; Merck; Neophore; Personal Genome Diagnostics; Seer; Zydecom
Research Funding - Merck (Inst)
Patents, Royalties, Other Intellectual Property - EP-2912468-B1 - Papanicolaou test for ovarian and endometrial cancers; EP-3322824-A1 - Detection of tumor-derived dna in cerebrospinal fluid; US-2005202465-A1 - Thymidylate synthase gene and metastasis; US-2010041048-A1 - Circulating Mutant DNA to Assess Tumor Dynamics; US-2013323167-A1 - Detecting and treating solid tumors through selective disruption of tumor vasculature; US-2014227271-A1 - Somatic mutations in atrx in brain cancer; US-2015252415-A1 - Arid1b and neuroblastoma; US-2015344970-A1 - Personalized Tumor Biomarkers; US-2016208340-A1 - TERT Promoter Mutations in Urothelial Neoplasia; US-2016273049-A1 - Systems and methods for analyzing nucleic acid (Inst); US-2017016075-A1 - Neoantigen analysis (Inst); US-2017267760-A1 - Checkpoint Blockade and Microsatellite Instability; US-2018086832-A1 - Hla-restricted epitopes encoded by somatically mutated genes; US-2018135044-A1 - Non-unique barcodes in a genotyping assay (Inst); US-2018171413-A1 - Head and neck squamous cell carcinoma assays; US-2018171413-A1 - Head and neck squamous cell carcinoma assays; US-2018171413-A1 - Head and neck squamous cell carcinoma assays; US-2018258490-A1 - Assaying ovarian cyst fluid; US-9976184-B2 - Mutations in pancreatic neoplasms; WO-2010118016-A2 - Digital quantification of dna methylation; WO-2012094401-A2 - Genes frequently altered in pancreatic neuroendocrine tumors; WO-2018071796-A2 - Compositions and methods for identifying functional anti-tumor t cell responses