The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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Microsatellite instability (MSI), mismatch repair (MMR), and tumor mutational burden (TMB) as predictive biomarkers for immune checkpoint inhibitor (ICI) effectiveness in real-world patients with metastatic colorectal cancer (mCRC).
 
Haley Ellis
No Relationships to Disclose
 
Samuel J Klempner
Stock and Other Ownership Interests - Nuvalent, Inc.; TP Therapeutics
Honoraria - Natera
Consulting or Advisory Role - Astellas Pharma; Bristol-Myers Squibb; Daiichi Sankyo/UCB Japan; Exact Sciences; Lilly; Merck; Mersana; Novartis; Pieris Pharmaceuticals; Sanofi/Aventis
Research Funding - BeiGene (Inst); Leap Therapeutics (Inst); Silverback Therapeutics (Inst)
Other Relationship - NCCN
 
Julia C. F. C. F. Quintanilha
Employment - Foundation Medicine
Stock and Other Ownership Interests - Roche
Patents, Royalties, Other Intellectual Property - Serial number 16/932002: Methods of identifying risk of bevacizumab-induced proteinuria and hypertension; Serial number 63/169301: Plasma levels of angiopoietin-2, VEGF-A, and VCAM-1 as markers of bevacizumab induced hypertension
 
Parvathi Myer
No Relationships to Disclose
 
Douglas I. Lin
Employment - Foundation Medicine
Stock and Other Ownership Interests - Roche
 
Nicole Panarelli
Honoraria - Aerie (I); Allergan (I); Bausch and Lomb (I); CorneaGen (I); Glaukos (I); New World Pharmaceuticals (I); Santen (I)
Consulting or Advisory Role - Aerie (I); Allergan (I); Bausch and Lomb (I); CorneaGen (I); Glaukos (I); New World Pharmaceuticals (I); Santen (I)
Speakers' Bureau - Aerie (I); Allergan (I); Bausch and Lomb (I); CorneaGen (I); Glaukos (I); New World Pharmaceuticals (I); Santen (I)
 
Virginia Fisher
Employment - Foundation Medicine; Foundation Medicine
Stock and Other Ownership Interests - Roche
 
Gerald Li
Employment - Foundation Medicine
Stock and Other Ownership Interests - Roche
 
Richard S.P. Huang
Employment - Roche/Foundation Medicine
Stock and Other Ownership Interests - Roche
Patents, Royalties, Other Intellectual Property - Patent on IHC; provisional patent on biomarkers and biomarker methodology.
 
Jeffrey S. Ross
Employment - Foundation Medicine
Leadership - Foundation Medicine
Stock and Other Ownership Interests - Foundation Medicine
Consulting or Advisory Role - Celsius Therapeutics; Tango Therapeutics
Research Funding - Foundation Medicine
 
Geoffrey R. Oxnard
Employment - Foundation Medicine
Stock and Other Ownership Interests - Roche
 
Ryon Graf
Employment - Epic Sciences; Foundation Medicine
Stock and Other Ownership Interests - Roche
Travel, Accommodations, Expenses - Epic Sciences; Foundation Medicine