Niraparib (NIRA) with abiraterone acetate and prednisone (AAP) in patients (pts) with metastatic castration-resistant prostate cancer (mCRPC) and homologous recombination repair (HRR) gene alterations: Second interim analysis (IA2) of MAGNITUDE.

Eleni  Efstathiou

Consulting or Advisory Role - Astellas Pharma; AstraZeneca; Merck Sharp & Dohme; Myovant Sciences; Pfizer; Sanofi

Speakers' Bureau - Astellas Pharma; AstraZeneca; Merck Sharp & Dohme; Myovant Sciences; Pfizer; Sanofi

Research Funding - Astellas Pharma; AstraZeneca; Merck Sharp & Dohme; Myovant Sciences; Pfizer; Sanofi

Matthew Raymond  Smith

Consulting or Advisory Role - Amgen; Astellas Pharma; Bayer; Janssen Oncology; Lilly; Novartis; Pfizer

Research Funding - Bayer (Inst); ESSA (Inst); Janssen Oncology (Inst); Lilly (Inst); ORIC Pharmaceuticals (Inst)

Shahneen  Sandhu

Honoraria - AstraZeneca (Inst); Bristol-Myers Squibb (Inst); Merck (Inst)

Consulting or Advisory Role - Amgen (Inst); AstraZeneca (Inst); Bristol-Myers Squibb/Roche (Inst); Genentech (Inst); Merck Sharp and Dohme (Inst); Novartis (Inst)

Speakers' Bureau - AstraZeneca (Inst); Bristol-Myers Squibb; Merck; Roche/Genentech

Research Funding - Amgen (Inst); AstraZeneca (Inst); Endocyte/Advanced Accelerator Applications (Inst); Genentech/Roche (Inst); Merck (Inst); Novartis (Inst); Pfizer (Inst); Roche/Genentech (Inst); Senhwa Biosciences (Inst)

(OPTIONAL) Uncompensated Relationships - AAA/Endocyte/Novartis (Inst)

Gerhardt  Attard

Honoraria - Astellas Pharma; Janssen; Janssen (I)

Consulting or Advisory Role - Abbott Laboratories; Astellas Pharma; AstraZeneca; Bayer; ESSA; Ferring; Janssen-Cilag; Medivation; Millennium; Novartis; Pfizer; Ventana Medical Systems; Veridex

Speakers' Bureau - Astellas Pharma; AstraZeneca; Ferring; Ipsen; Janssen; Sanofi; Takeda; Ventana Medical Systems

Research Funding - Arno Therapeutics (Inst); Innocrin Pharma (Inst); Janssen (Inst)

Patents, Royalties, Other Intellectual Property - I am on The ICR rewards to inventors list of abiraterone acetate.

Travel, Accommodations, Expenses - Abbott Laboratories; Astellas Pharma; Astellas Pharma (I); Bayer; ESSA; Ferring; Janssen; Janssen (I); Medivation; Pfizer; Ventana Medical Systems

Other Relationship - Institute of Cancer Research

Marniza  Saad

Honoraria - Amgen; Astellas Pharma; AstraZeneca; Cipla; Eisai; Ipsen; Johnson&Johnson; Novartis; Pfizer

Consulting or Advisory Role - AstraZeneca; BMS; Johnson&Johnson; Merck; MSD; Novartis; Viatris

Research Funding - Johnson & Johnson; MSD

David  Olmos

Honoraria - Astellas Pharma (Inst); Bayer; Janssen

Consulting or Advisory Role - AstraZeneca (Inst); Bayer; Bayer (Inst); Clovis Oncology; Daiichi Sankyo; Janssen; Janssen (Inst); MSD Oncology

Research Funding - Astellas Medivation (Inst); AstraZeneca (Inst); Bayer (Inst); Genentech/Roche (Inst); Janssen (Inst); MSD Oncology (Inst); Pfizer (Inst); Tokai Pharmaceuticals (Inst)

Travel, Accommodations, Expenses - Astellas Pharma; AstraZeneca Spain; Bayer; Ipsen; Janssen; Roche

Elena  Castro

Honoraria - Astellas Pharma; AstraZeneca; Bayer; Clovis Oncology; Janssen-Cilag; Pfizer; Roche

Consulting or Advisory Role - Astellas Pharma; AstraZeneca; Bayer; Janssen; Merck; MSD Oncology; Pfizer

Speakers' Bureau - AstraZeneca; Janssen; Novartis; Pfizer

Research Funding - AstraZeneca (Inst); Bayer (Inst); Janssen (Inst); SYNLAB (Inst)

Expert Testimony - Pfizer

Travel, Accommodations, Expenses - Astellas Pharma; AstraZeneca; Bayer; Janssen; Roche

Guilhem  Roubaud

No Relationships to Disclose

Andrea Juliana  Gomes

Honoraria - Astellas Pharma; AstraZeneca; Bayer; Janssen Oncology

Consulting or Advisory Role - Janssen Oncology

Speakers' Bureau - Astellas Pharma; Bayer; Janssen Oncology

Research Funding - AstraZeneca; Bayer; Janssen Oncology; MSD Oncology; Roche

Eric Jay  Small

Stock and Other Ownership Interests  - Fortis; Harpoon Therapeutics; Teon Therapeutics

Honoraria - Janssen; Johnson and Johnson

Consulting or Advisory Role - Fortis; Janssen Oncology; Teon Therapeutics

Dana E.  Rathkopf

Consulting or Advisory Role - AstraZeneca; Bayer; Genentech; Janssen; Myovant Sciences

Research Funding - AstraZeneca (Inst); Bayer (Inst); Celgene (Inst); Ferring (Inst); Genentech/Roche (Inst); Janssen Oncology (Inst); Medivation (Inst); Millennium (Inst); Novartis (Inst); Phosplatin Therapeutics (Inst); Taiho Pharmaceutical (Inst); Takeda (Inst); TRACON Pharma (Inst)

Howard  Gurney

Consulting or Advisory Role - Astellas Pharma; AstraZeneca; Bristol-Myers Squibb; Ipsen; Janssen-Cilag; Merck Serono; Merck Sharp & Dohme; Pfizer; Roche

Speakers' Bureau - AstraZeneca; Merck Serono

Travel, Accommodations, Expenses - AstraZeneca

Wonho  Jung

No Relationships to Disclose

Gary  Mason

Employment - Janssen Research & Development; Merck (I)

Stock and Other Ownership Interests  - Johnson & Johnson; Merck (I)

Travel, Accommodations, Expenses - Janssen Research & Development

Peter St. John  Francis

Employment - Johnson and Johnson

Stock and Other Ownership Interests  - Johnson and Johnson

Travel, Accommodations, Expenses - Johnson and Johnson

George C.  Wang

Employment - Janssen

Stock and Other Ownership Interests  - Janssen

Daphne  Wu

Employment - Johnson & Johnson/Janssen

Brooke  Diorio

Employment - Janssen

Stock and Other Ownership Interests  - Janssen

Angela Mennicke  Lopez- Gitlitz

Employment - Janssen

Stock and Other Ownership Interests  - Janssen

Kim N.  Chi

Honoraria - Astellas Pharma; AstraZeneca; Bayer; Janssen; Merck; POINT Biopharma; Roche

Consulting or Advisory Role - Amgen; Astellas Pharma; AstraZeneca; Bayer; Constellation Pharmaceuticals; Daiichi Sankyo; ESSA; Janssen; Merck; POINT Biopharma; Roche; Sanofi

Research Funding - Astellas Pharma (Inst); AstraZeneca (Inst); Bayer (Inst); Bristol-Myers Squibb (Inst); ESSA (Inst); Janssen (Inst); Merck (Inst); Novartis (Inst); Pfizer (Inst); Roche (Inst); Sanofi (Inst)

Expert Testimony - AstraZeneca; Novartis