The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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Circulating tumor DNA analysis of IMbassador250: Association of ctDNA fraction, AR alterations and therapy outcome in mCRPC.
 
Christopher Sweeney
Stock and Other Ownership Interests - Leuchemix
Consulting or Advisory Role - Amgen; Astellas Pharma; AstraZeneca; Bayer; Genentech/Roche; Janssen Biotech; Lilly; Pfizer; POINT Biopharma; Sanofi
Research Funding - Astellas Pharma (Inst); Bayer (Inst); Dendreon; Janssen Biotech (Inst); Pfizer (Inst); Sanofi (Inst)
Patents, Royalties, Other Intellectual Property - Leuchemix, Parthenolide, Dimethylaminoparthenolide. Exelixis: Abiraterone plus cabozantinib combination
 
Ryon Graf
Employment - Epic Sciences; Foundation Medicine
Stock and Other Ownership Interests - Roche
Travel, Accommodations, Expenses - Epic Sciences; Foundation Medicine
 
David Fabrizio
Employment - Foundation Medicine
Stock and Other Ownership Interests - Roche
Patents, Royalties, Other Intellectual Property - 1. Novel PD-L1 binding polypeptides for imaging 2. Methods and systems for evaluating tumor mutational burden 3. Therapeutic and diagnostic methods for cancer 4. Targeted therapeutics based on engineered proteins for tyrosine kinase receptors, including
 
Kobe Yuen
Employment - Genentech/Roche
Stock and Other Ownership Interests - Roche
 
Matthew J. Wongchenko
Employment - Genentech/Roche
Stock and Other Ownership Interests - Genentech/Roche
 
Pratyush Gupta
Employment - CellMax Life; Genentech
Stock and Other Ownership Interests - CellMax Life; Genentech
Research Funding - CellMax Life
Patents, Royalties, Other Intellectual Property - Patent(s) in progress
Travel, Accommodations, Expenses - CellMax Life; Genentech
 
Priti Hegde
Employment - Foundation Medicine
Leadership - Foundation Medicine; Foundation Medicine; Foundation Medicine; TCR2 Therapeutics
Stock and Other Ownership Interests - Roche/Genentech; TCR2 Therapeutics
Consulting or Advisory Role - Bolt Biotherapeutics
Patents, Royalties, Other Intellectual Property - Role of TMB as a biomarker for immunotherapy and use of a CGP panel in describing TMB in patient tumors
 
Geoffrey R. Oxnard
Employment - Foundation Medicine
Stock and Other Ownership Interests - Roche
 
Thomas Powles
Consulting or Advisory Role - Astellas Pharma; AstraZeneca; Bristol-Myers Squibb; Eisai; Exelixis; Incyte; Ipsen; Johnson & Johnson; MashupMD; Merck Serono; MSD; Novartis; Pfizer; Roche; Seagen
Research Funding - Astellas Pharma; AstraZeneca; Bristol-Myers Squibb; Eisai; Exelixis; Ipsen; Johnson & Johnson; Merck Serono; MSD; Novartis; Pfizer; Roche; Seagen
Travel, Accommodations, Expenses - AstraZeneca; Ipsen; MSD; Pfizer; Roche