The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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Population pharmacokinetic-pharmacodynamic model of nirogacestat effects on B-cell maturation antigen in healthy subjects.
 
Todd Shearer
Stock and Other Ownership Interests - SpringWorks Therapeutics
Patents, Royalties, Other Intellectual Property - Signatory of patent application for the use of nirogacestat in multiple myeloma and in ovarian cancers as Vice President of Clinical Pharmacology at SpringWorks Therapeutics.
 
Rex L. Williams
Employment - Regeneron (I); SpringWorks Therapeutics
Stock and Other Ownership Interests - Pfizer; SpringWorks Therapeutics
Patents, Royalties, Other Intellectual Property - Applications for compositions and methods.
Travel, Accommodations, Expenses - SpringWorks Therapeutics
 
Mark Johnson
Employment - Precision Biosciences; SpringWorks Therapeutics
Stock and Other Ownership Interests - Precision Biosciences; SpringWorks Therapeutics
Patents, Royalties, Other Intellectual Property - Signatory on methods patent.
 
Ewa Cendrowicz
Employment - ICON Clinical Research
 
Cathrine Leonowens
Stock and Other Ownership Interests - Agilent; Alcon; Becton Dickinson; BioGenTech; Charles River Associates; GlaxoSmithKline; Haemonetics; IDEXX Laboratories; Integra LifeSciences; Jazz Pharmaceuticals; Johnson & Johnson/Janssen; Lilly
Consulting or Advisory Role - Allucent; CytomX Therapeutics; DAAN Biotherapeutics; Isola; Johnson & Johnson/Janssen; Multidisciplinary Association for Psychedelic Studies; SpringWorks Therapeutics
Travel, Accommodations, Expenses - CytomX Therapeutics
 
Margaret Smith
Employment - SpringWorks Therapeutics
Stock and Other Ownership Interests - SpringWorks Therapeutics
 
Todd Baughman
Employment - SpringWorks Therapeutics
Stock and Other Ownership Interests - SpringWorks Therapeutics
 
Caroline J. Breitbach
Employment - SpringWorks Therapeutics
Stock and Other Ownership Interests - SpringWorks Therapeutics
 
L. Mary Smith
Employment - SpringWorks Therapeutics
Leadership - SpringWorks Therapeutics
Stock and Other Ownership Interests - SpringWorks Therapeutics
 
Shinta Cheng
Employment - SpringWorks Therapeutics
Stock and Other Ownership Interests - SpringWorks Therapeutics
Patents, Royalties, Other Intellectual Property - Signatory of patent application for the use of nirogacestat in multiple myeloma and in ovarian cancers as Vice President of Clinical Development at SpringWorks Therapeutics. (Inst)