The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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A first-in-human trial of intravesical enfortumab vedotin (EV), an antibody-drug conjugate (ADC), in patients with non-muscle invasive bladder cancer (NMIBC): Interim results of a phase 1 study (EV-104).
 
Ashish M. Kamat
Honoraria - AstraZeneca (I); Tesaro (I)
Consulting or Advisory Role - Asieris Pharmaceuticals; Astellas Pharma; Biological Dynamics; Bristol-Myers Squibb; CG Oncology; Eisai; EnGeneIC; FerGene; Imagin Medical; Incyte; Janssen; Medac; Merck; Photocure; Protara Therapeutics; Roche; Seagen; Sesen Bio; Theralase; TMC Innovation; Urogen pharma; US Biotest
Research Funding - Adolor; Bristol-Myers Squibb; FKD Therapies; Heat Biologics; Janssen/Taris; Merck; NIH; Patient-Centered Outcomes Research Institute (PCORI); Photocure; Seagen; SWOG; Taris BioMedical; The Leo & Anne Albert Institute for Bladder Cancer Care and Research (AIBCCR)
Patents, Royalties, Other Intellectual Property - Patent: CyPRIT (Cytokine Predictors of Response to Intravesical Therapy) joint with UT MD Anderson Cancer Center
Other Relationship - European Urology Oncology; International Bladder Cancer Group (IBCG); International Bladder Cancer Network; Journal of Urology; UroToday
 
Yair Lotan
Stock and Other Ownership Interests - C2i genomics; CAPs medical; Nanorobotics; Vessi Medical
Consulting or Advisory Role - Abbvie; Ambu; AstraZeneca; Aura Biosciences; BMS; C2i genomics; caps medical; Cleveland Diagnostics; Convergent Genomics; Fergene; Merck; Nanogen Biopharmaceutical; Nanorobotics; Nucleix; pacific edge; Photocure; Seagen; Stimit; Urogen pharma; verity pharmaceuticals; Vessi Medical; virtuoso surgical; Xcures
Research Funding - Abbott Molecular (Inst); Augmenix; BioCancell (Inst); Cepheid; Cepheid (Inst); GenomeDx (Inst); MDxHealth (Inst); pacific edge; pacific edge (Inst); Photocure (Inst); storz (Inst)
 
Morgan Roupret
Consulting or Advisory Role - Arquer Diagnostics; GlaxoSmithKline; Intuitive Surgical; Ipsen; Janssen-Cilag; Lilly; MSD; Roche; Sanofi; Takeda
Travel, Accommodations, Expenses - Astellas Pharma; Coloplast
 
Gary D. Steinberg
Stock and Other Ownership Interests - CG Oncology; Epivax Therapeutics; Urogen pharma
Honoraria - Aduro Biotech; AstraZeneca; Bristol-Myers Squibb; CG Oncology; enGene; Epivax Oncology; fergene; Ferring; Fidia Farmaceutici S. p. A.; FKD Therapies; Janssen Oncology; MDxHealth; Merck; Pfizer; Photocure; Roche/Genentech; Seagen; Sesen Bio; Urogen pharma
Consulting or Advisory Role - Boston Scientific; CG Oncology; Fidia Farmaceutici S. p. A.; Heat Biologics; Imvax; MDxHealth; Merck; NanOlogy; Natera; Nonagen Bioscience; photocure; Roche/Genentech; Taris BioMedical; Verity Pharmaceuticals
 
Brant A. Inman
Consulting or Advisory Role - Combat Medical; Urogen pharma
Research Funding - CG Oncology (Inst); FKD Therapies (Inst); Genentech/Roche (Inst); Janssen Oncology (Inst); Seagen (Inst); Taris BioMedical (Inst)
 
Thomas Powles
Honoraria - Astellas Pharma; AstraZeneca; BMS GmbH & Co. KG; Eisai; Exelixis; Exelixis; Gilead Sciences; Incyte; Ipsen; Johnson & Johnson/Janssen; MashupMD; MashupMD; Merck; Merck Serono; Merck Serono; Merck Sharp & Dohme LLC; Novartis; Pfizer; Roche; Seagen
Consulting or Advisory Role - Astellas Pharma; AstraZeneca; Bristol-Myers Squibb; Eisai; Exelixis; Incyte; Ipsen; Johnson & Johnson; MashupMD; Merck; Merck Serono; MSD; Novartis; Pfizer; Roche; Seagen
Research Funding - Astellas Pharma; AstraZeneca; Bristol-Myers Squibb; Eisai; Exelixis; Ipsen; Johnson & Johnson; Merck Serono; MSD; Novartis; Pfizer; Roche; Seagen
Travel, Accommodations, Expenses - AstraZeneca; Ipsen; MSD; Pfizer; Roche
 
J. Palou Redorta
Consulting or Advisory Role - Arquer diagnostics; AstraZeneca; BMS; Combat Medical; Janssen
 
Sima P. Porten
Honoraria - photocure
Consulting or Advisory Role - Bristol-Myers Squibb; KDx Diagnostics; Photocure; Protara Therapeutics
Research Funding - Photocure (Inst)
Travel, Accommodations, Expenses - Bristol-Myers Squibb
 
Girish S. Kulkarni
Honoraria - Abbvie; AstraZeneca Canada; Bayer; BioSyent; Knight Pharmaceuticals; Tersera
Consulting or Advisory Role - Bristol-Myers Squibb; EMD Serono; Ferring; Janssen Oncology; Merck; Theralase; Verity Pharmaceuticals
 
Edward M. Uchio
Research Funding - Ambry Genetics; Bayer; Bristol-Myers Squibb/Pfizer; CG Oncology; Clovis Oncology; Exact Sciences; GenomeDx; Genomic Health; Janssen Oncology; Merck; Merit Medical Systems; Myovant Sciences; Myovant Sciences; Myriad Genetics; Pfizer; Seagen; Veracyte
(OPTIONAL) Uncompensated Relationships - Bayer; Genomic Health; Janssen Oncology; Merck; Myriad Genetics; Pfizer
 
Seema Rao Gorla
Employment - Astellas Pharma
Research Funding - Astellas Pharma
Travel, Accommodations, Expenses - Astellas Pharma
 
Gabriel P. Haas
Employment - Astellas Pharma
 
Yao Yu
Employment - Seagen
Stock and Other Ownership Interests - Seagen
 
Yen Lin Chia
Employment - Seagen
Stock and Other Ownership Interests - Seagen
Travel, Accommodations, Expenses - Seagen
 
Matthew Birrenkott
Employment - Seagen
 
Max R. Kates
Honoraria - Astellas Pharma
Consulting or Advisory Role - Astellas Pharma; Genesis Biotechnology Group; Nanology; pacific edge; photocure