The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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A phase Ib/II study of intermittent talazoparib plus temozolomide in patients with metastatic castration-resistant prostate cancer (mCRPC) and no mutations in DNA damage repair (DDR).
 
Karen A. Autio
Research Funding - Amgen (Inst); AstraZeneca (Inst); CytomX Therapeutics (Inst); GlaxoSmithKline (Inst); Lilly (Inst); Merck (Inst); Pfizer (Inst); Pfizer (Inst); Tizona Therapeutics, Inc. (Inst)
 
Christos Kyriakopoulos
Stock and Other Ownership Interests - Biogen; Epic Systems (I)
Consulting or Advisory Role - AVEO; EMD Serono; Exelixis; Janssen Oncology; Janssen Oncology; Sanofi
Research Funding - AstraZeneca; ESSA; Gilead Sciences; Pionyr; Sanofi
 
Han Xiao
No Relationships to Disclose
 
Hamid Emamekhoo
Consulting or Advisory Role - Cardinal Health; Exelixis; Seagen; Seagen
 
Daniel Costin Danila
Honoraria - Angle; Astellas Pharma; AxImmune; Cambridge Healthtech Institute; Clovis Oncology; Pfizer; Pfizer
Consulting or Advisory Role - Angle; AxImmune; BioView; Clovis Oncology; Pfizer; Sanador
Research Funding - Amgen (Inst); Biosplice (Inst); Janssen Research & Development (Inst); Prostate Cancer Foundation
Patents, Royalties, Other Intellectual Property - GENE EXPRESSION PROFILE ASSOCIATED WITH PROSTATE CANCER
 
Michael Edward Devitt
Consulting or Advisory Role - Astellas Pharma; Seagen
Research Funding - Arvinas (Inst); Kangpu Biopharmaceuticals (Inst); Propella Therapeutics (Inst); Propella Therapeutics (Inst); Seagen (Inst); Syneos Health (Inst); Veru (Inst)
 
Elyn Riedel
No Relationships to Disclose
 
Mehrin Jan
No Relationships to Disclose
 
Howard I. Scher
Honoraria - Arsenal Capital; Elsevier
Consulting or Advisory Role - AIQ Global; Bayer; Genzyme; Janssen Research & Development; Pfizer; Promontory Therapeutics; Regeneron; WIRB-Copernicus Group
Research Funding - AIQ Solutions (Inst); Biodesix (Inst); Epic Sciences (Inst); Janssen (Inst); Thermofisher Scientific Biomarkers (Inst)
Patents, Royalties, Other Intellectual Property - BioNTech -Intellectual Property Rights; Elucida Oncology - Intellectual Property Rights; MabVAX - Intellectual Property Rights; Y-mAbs Therapeutics, Inc - Intellectual Property Rights
Travel, Accommodations, Expenses - Bayer; Biodesix; Epic Sciences; Promontory Therapeutics; Prostate Cancer Foundation; WIRB-Copernicus Group