The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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A phase 1, multicenter, open-label study of a new BRAF inhibitor ABM-1310 in adult patients (pts) with BRAFv600-mutated solid tumors.

Sarina A.  Piha-Paul

Consulting or Advisory Role - CRC Oncology

Research Funding - Abbvie (Inst); ABM (Inst); Acepodia (Inst); Alkermes (Inst); Aminex (Inst); Amphivena Therapetics, Inc. (Inst); Biomarin (Inst); Boehringer Ingelheim (Inst); Bristol Myers Squib (Inst); Cerulean Pharma (Inst); Chugai Pharma (Inst); Curis (Inst); Cyclacel (Inst); Daichi Sanko (Inst); ENB Therapeutics (Inst); Epigenetix (Inst); F-Star Beta Limited (Inst); F-Star Therapeutics, Ltd. (Inst); Five Prime Therapeutics (Inst); Gene Quantum (Inst); Genmab (Inst); Gilead Sciences (Inst); GlaxoSmithKline (Inst); Helix BioPharma (Inst); Hengrui Pharmaceutical  (Inst); HiberCell (Inst); Immorna (Inst); Immunomedics (Inst); Incyte (Inst); Jacobio (Inst); Jiangsu Simcere Pharmaceutical Co. Ltd. (Inst); Lilly (Inst); Lytix Biopharma (Inst); MedImmune (Inst); Medivation (Inst); Merck Sharp and Dohme Corp. (Inst); Nectin Therapeutics (Inst); NIH/NCI (Inst); Novartis (Inst); Pfizer (Inst); Phanes Therapeutics (Inst); Pieris Pharmaceuticals (Inst); Principa Biopharma (Inst); Puma Biotechnology (Inst); Purinomia (Inst); RAPT Therapeutics (Inst); Replimune (Inst); Seagen (Inst); Silverback Therapeutics (Inst); Synlogic (Inst); Taiho Oncology (Inst); Tesaro (Inst); TransThera Biosciences (Inst); ZielBio (Inst)

Seema  Nagpal

Consulting or Advisory Role - Biocept; Mirati Therapeutics; Novocure; Nurix; Pyramid Biosciences; Seagen

Research Funding - Agios (Inst); Berg Pharma (Inst); Inovio Pharmaceuticals (Inst); PharmAbcine (Inst)

Amy M.  Weise

Employment - N/A

Leadership - N/A

Stock and Other Ownership Interests  - N/A

Honoraria - N/A

Consulting or Advisory Role - N/A

Speakers' Bureau - N/A

Research Funding - N/A

Patents, Royalties, Other Intellectual Property - N/A

Expert Testimony - N/A

Travel, Accommodations, Expenses - N/A

Other Relationship - N/A

Fadi S.  Braiteh

Honoraria - AstraZeneca; AstraZeneca; Daiichi Sankyo; Deciphera; Eisai; EMD Serono; Fresenius Kabi; Genentech/Roche; Guardant Health; Ipsen; Lilly; Seagan; Stemline Therapeutics

Consulting or Advisory Role - AstraZeneca; Deciphera; Eisai; Guardant Health; Ipsen; Lilly; Sanofi

Speakers' Bureau - AstraZeneca; Bristol-Myers Squibb; Deciphera; EMD Serono; Genentech/Roche; Guardant Health; Jazz Pharmaceuticals; Lilly; Pfizer; Seagan; Taiho Pharmaceutical

Travel, Accommodations, Expenses - Bristol-Myers Squibb; EMD Serono; Fresenius Kabi; Incyte; Novartis; Regeneron; Roche/Genentech; Stemline Therapeutics; Taiho Pharmaceutical

Chen  Chen

Employment - ABM

Leadership - ABM

Stock and Other Ownership Interests  - ABM

Patents, Royalties, Other Intellectual Property - ABM

Charles Qing  Huang

Employment - ABM

Leadership - ABM

Stock and Other Ownership Interests  - ABM

Travel, Accommodations, Expenses - ABM

William  Liu

Employment - ABM; BeiGene (I)

Stock and Other Ownership Interests  - BeiGene Beijing; BeiGene Beijing (I)

Travel, Accommodations, Expenses - ABM

Yong  Hu

Employment - ABM

Leadership - ABM

Stock and Other Ownership Interests  - ABM

Honoraria - ABM

Travel, Accommodations, Expenses - ABM

Zane  Yang

Employment - ABM

Stock and Other Ownership Interests  - Amgen Astellas BioPharma; Johnson & Johnson (I); Spectrum Therapeutics

Expert Testimony - Johnson & Johnson (I)

Travel, Accommodations, Expenses - ABM

Katy K.  Tsai

Consulting or Advisory Role - Bristol-Myers Squibb

Research Funding - ABM (Inst); BioAtla (Inst); Bristol-Myers Squibb (Inst); Genentech (Inst); Oncosec (Inst); OnKure (Inst); Pfizer (Inst); Regeneron (Inst); Replimune (Inst)