The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
Open Payments is a public database containing information reported by companies about payments made to US-licensed physicians (Open Payments)
Interim analyses (IA) of the giredestrant (G), G + abemaciclib (A), and G + ribociclib (R) arms in MORPHEUS Breast Cancer (BC): A phase I/II study of G treatment (tx) combinations in patients (pts) with estrogen receptor-positive, HER2-negative locally advanced/metastatic BC (ER+, HER2– LA/mBC).
 
Mafalda Oliveira
Honoraria - Eisai Europe; Gilead Sciences; MSD; Novartis; Pfizer; Roche; SeaGen
Consulting or Advisory Role - AstraZeneca; Daiichi Sankyo/Astra Zeneca; Gilead Sciences; ITeos Therapeutics; Relay Therapeutics; Roche/Genentech; Seagen
Research Funding - AstraZeneca (Inst); Ayala Pharmaceuticals (Inst); Boehringer Ingelheim (Inst); Gilead Sciences (Inst); GlaxoSmithKline (Inst); Roche/Genentech (Inst); Seagen (Inst); Zenith Epigenetics (Inst)
Travel, Accommodations, Expenses - AstraZeneca Spain; Eisai; Gilead Sciences; Pierre Fabre
 
Amir Sonnenblick
Consulting or Advisory Role - AstraZeneca; Gilead Sciences; Lilly; MSD; Novartis; Pfizer; Progenetics; Roche
Speakers' Bureau - Lilly; Novartis; Pfizer; Roche; Teva
Research Funding - Novartis (Inst); Roche (Inst)
Travel, Accommodations, Expenses - Celgene; Medison; MSD; NeoPharm; Roche
 
Hope S. Rugo
Consulting or Advisory Role - Blueprint Medicines; Napo Pharmaceuticals; Puma Biotechnology; Scorpion Therapeutics
Research Funding - Astellas Pharma (Inst); AstraZeneca (Inst); Daiichi Sankyo (Inst); Genentech (Inst); Gilead Sciences (Inst); GlaxoSmithKline (Inst); Lilly (Inst); Merck (Inst); Novartis (Inst); OBI Pharma (Inst); Pfizer (Inst); Pionyr (Inst); Sermonix Pharmaceuticals (Inst); Taiho Oncology (Inst); Veru (Inst)
Travel, Accommodations, Expenses - AstraZeneca; Gilead Sciences; Merck
 
Kyung Hae Jung
Consulting or Advisory Role - AstraZeneca; Bixink; Celgene; Eisai; Everest Medicine; Merck; Novartis; Roche; Takeda
 
Einav Gal Yam
Honoraria - AstraZeneca; Lilly; msd; Pfizer; Roche
Consulting or Advisory Role - AstraZeneca; Lilly; MSD Oncology
Travel, Accommodations, Expenses - Pfizer
 
Sara A. Hurvitz
Stock and Other Ownership Interests - Ideal Implant (I); ROM Tech (I)
Honoraria - Daiichi Sankyo/Astra Zeneca
Research Funding - Ambryx (Inst); Amgen (Inst); Arvinas (Inst); AstraZeneca/Daiichi Sankyo (Inst); Bayer (Inst); Biomarin (Inst); Cascadian Therapeutics (Inst); CytomX Therapeutics (Inst); Daiichi Sankyo (Inst); Dantari (Inst); Dignitana (Inst); G1 Therapeutics (Inst); Genentech/Roche (Inst); Gilead Sciences (Inst); GlaxoSmithKline (Inst); Greenwich LifeSciences (Inst); Immunomedics (Inst); Lilly (Inst); Macrogenics (Inst); Merrimack (Inst); Novartis (Inst); OBI Pharma (Inst); Orinove (Inst); Pfizer (Inst); Phoenix Molecular Designs (Inst); Pieris Pharmaceuticals (Inst); Puma Biotechnology (Inst); Radius Health (Inst); Samumed (Inst); sanofi (Inst); Seagen (Inst); Zymeworks (Inst)
Travel, Accommodations, Expenses - Lilly
Other Relationship - Pfizer; Roche
 
Cristina Hernando
Consulting or Advisory Role - Novartis; Pfizer
Travel, Accommodations, Expenses - AstraZeneca/Daiichi Sankyo; Novartis; Pfizer; Roche
 
Seock-Ah Im
Consulting or Advisory Role - Amgen; AstraZeneca; Daiichi Sankyo; Eisai; GlaxoSmithKline; Hanmi; Lilly; MSD; Novartis; Pfizer; Roche/Genentech
Research Funding - AstraZeneca (Inst); Boryung Pharmaceuticals (Inst); Daewoong Pharmaceutical (Inst); Eisai (Inst); Pfizer (Inst); Roche/Genentech (Inst)
Other Relationship - Roche
 
Vanessa Breton
Employment - Roche
Stock and Other Ownership Interests - Roche
Research Funding - Roche
 
Ann Collier
Employment - Genentech/Roche
Stock and Other Ownership Interests - Roche
Research Funding - Genentech/Roche
Travel, Accommodations, Expenses - Genentech/Roche
 
Richard B. Schwab
Stock and Other Ownership Interests - Biosplice (I)
Patents, Royalties, Other Intellectual Property - The patent covers sialylated glycans and antibodies that specifically bind to them for early detection and diagnosis of cancer. (Inst)
 
Jing Zhu
Employment - Genentech
Stock and Other Ownership Interests - Roche
Research Funding - Roche
 
Joohyuk Sohn
Stock and Other Ownership Interests - Daiichi Sankyo (I)
Research Funding - AstraZeneca (Inst); Boehringer Ingelheim (Inst); Daiichi Sankyo (Inst); GlaxoSmithKline (Inst); Lilly (Inst); MSD (Inst); Novartis (Inst); Pfizer (Inst); Roche (Inst); Sanofi (Inst); Seagan (Inst)