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NOTOS: A pivotal study of navtemadlin, a first-in-class mouse double minute 2 inhibitor (MDM2i), in patients (pts) with TP53 wild-type (TP53WT) Merkel cell carcinoma (MCC) for whom anti PD-1/L1 therapy has failed. |
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Consulting or Advisory Role - Castle Biosciences; Regeneron; Replimune |
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Consulting or Advisory Role - Rain Therapeutics; SpringWorks Therapeutics |
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Honoraria - Array BioPharma; Bristol Myers Squibb; EMD Serono; Exicure; Novartis; Pfizer; Sanofi/Regeneron |
Consulting or Advisory Role - Array BioPharma; Bristol-Myers Squibb; EMD Serono; Exicure; Novartis; Pfizer; Sanofi/Regeneron |
Research Funding - Bristol Myers Squibb Foundation (Inst); EMD Serono (Inst); exicure (Inst); Novartis (Inst); Pfizer (Inst); Sanofi/Regeneron (Inst) |
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Consulting or Advisory Role - Elsevier; Hoosier Cancer Research Network; Via Oncology |
Research Funding - Bristol-Myers Squibb (Inst); Kartos Therapeutics (Inst); Pfizer/Array (Inst); Pfizer/EMD Serono (Inst) |
Travel, Accommodations, Expenses - AIM at Melanoma Foundation |
Other Relationship - Pfizer/Array |
(OPTIONAL) Uncompensated Relationships - American Association of Clinical Endocrinology; ASCO; NCCN |
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Honoraria - Blueprint Medicines; BMS france; MSD Oncology; Pierre Fabre |
Consulting or Advisory Role - Pierre Fabre |
Travel, Accommodations, Expenses - BMS France; MSD Oncology; Pierre Fabre |
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Consulting or Advisory Role - Instil Bio; Signatera |
Research Funding - Biohaven Pharmaceuticals (Inst); Checkmate Pharmaceuticals (Inst); Morphogenesis (Inst); Replimune (Inst); Shattuck Labs (Inst) |
Patents, Royalties, Other Intellectual Property - UpToDate |
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Employment - Dana-Farber Cancer Institute |
Honoraria - Bristol-Myers Squibb; Kura Oncology |
Consulting or Advisory Role - Bicara Therapeutics; Boxer Capital; Bristol-Myers Squibb; Exicure; General Catalyst; KSQ Therapeutics; Kura Oncology; Merck; Naveris; Prelude Therapeutics; Rain Therapeutics; Remix Therapeutics; Sanofi; SIRPant Immunotherapeutics |
Research Funding - Actuate Therapeutics (Inst); Bicara Therapeutics (Inst); Bristol-Myers Squibb (Inst); Conquer Cancer, the ASCO Foundation; Elevar Therapeutics (Inst); Exicure (Inst); Gateway for Cancer Research; Genzyme (Inst); GlaxoSmithKline (Inst); Kartos Therapeutics (Inst); Kite/Gilead (Inst); Kite/Gilead (Inst); NantKwest, (Inst); Regeneron (Inst); Secura Bio (Inst); V Foundation |
Expert Testimony - Aaronson Rappaport Feinstein & Deutsch; Ahmuty, Demers, & McManus; Wilson Elser Moskowitz Edelman & Dicker, LLP |
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Honoraria - Amgen; Bristol-Myers Squibb; Incyte; MSD; Novartis; Pfizer; Pierre Fabre; Roche |
Consulting or Advisory Role - Amgen; Bristol-Myers Squibb; Merck Serono; MSD; Novartis; Pierre Fabre; Roche; Sanofi |
Speakers' Bureau - Amgen; Bristol-Myers Squibb; MSD; Novartis; Roche |
Research Funding - Bristol-Myers Squibb (Inst); Roche (Inst) |
Travel, Accommodations, Expenses - Bristol-Myers Squibb; MSD; Novartis; Pierre Fabre; Sanofi |
Other Relationship - Avantis Medical Systems; BMS; InflaRx; Jazz Pharmaceuticals; MSD; Novartis; Pierre Fabre; Sanofi |
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No Relationships to Disclose |
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Consulting or Advisory Role - BostonGene; Castle Biosciences; replimune; Sanofi/Regeneron |
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Honoraria - 4SC; Agenus; AstraZeneca; Bristol-Myers Squibb; Daiichi Sankyo Japan; Erasca, Inc; immatics; Immunocore; InflarxGmbH; LabCorp; Merck Serono; Merck Sharp & Dohme; NeraCare GmbH; Novartis; Novigenix; Pamgene; Pfizer; Philogen; Pierre Fabre; Regeneron; Replimune; Roche/Genentech; Sanofi/Regeneron; Seagen; Sun Pharma; Ultimovacs |
Consulting or Advisory Role - Agenus; AstraZeneca; Bristol-Myers Squibb; Daiichi Sankyo; Erasca, Inc; immatics; Immunocore; Merck Sharp & Dohme; NeraCare GmbH; Novartis; Pierre Fabre; Replimune; Roche/Genentech; Sanofi/Regeneron |
Speakers' Bureau - Bristol-Myers Squibb; Merck KGaA; Merck Sharp & Dohme; Novartis; Pierre Fabre; Sanofi/Regeneron |
Research Funding - Amgen (Inst); Array BioPharma/Pfizer (Inst); Bristol-Myers Squibb (Inst); MSD Oncology (Inst); Novartis (Inst); Roche (Inst) |
Travel, Accommodations, Expenses - Bristol-Myers Squibb; Merck Serono; Merck Sharp & Dohme; Novartis; Pierre Fabre; Roche/Genentech; Sanofi/Regeneron |
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Honoraria - Bristol-Myers Squibb; MSD; Novartis; Pierre Fabre |
Consulting or Advisory Role - Bristol-Myers Squibb; MSD; Novartis; Pierre Fabre |
Travel, Accommodations, Expenses - Bristol-Myers Squibb; MSD; Novartis; Pierre Fabre |
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Honoraria - Almirall Hermal GmbH; Bristol-Myers Squibb; LEO Pharma; MSD; Novartis; Sanofi/Aventis |
Consulting or Advisory Role - Almirall Hermal GmbH; Bristol-Myers Squibb; Immunocore; InflaRx; MSD; Novartis; Pierre Fabre; Sanofi/Aventis; Sanofi/Regeneron |
Research Funding - Almirall Hermal GmbH (Inst); Bristol-Myers Squibb (Inst); immatics (Inst); InflaRx (Inst); IO Biotech (Inst); Kartos Therapeutics (Inst); Pfizer (Inst) |
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No Relationships to Disclose |
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Consulting or Advisory Role - 4SC; AstraZeneca; Bayer; Bio-AI Health; Boehringer Ingelheim; Bristol-Myers Squibb; Daiichi Sankyo; Eisai; Idera; Immunocore; Italfarmaco; ITeos Therapeutics; Lunaphore Technologies; Medicenna; Merck Serono; Merck Sharp & Dohme; Nektar; Nouscom; Novartis; OncoSec; Pfizer; Pierre Fabre; Regeneron; Replimune; Roche/Genentech; Sandoz; Sanofi; Seagen; Sun Pharma; Ultimovacs; ValoTx |
Research Funding - Bristol-Myers Squibb (Inst); Pfizer (Inst); Roche/Genentech (Inst); Sanofi (Inst) |
Travel, Accommodations, Expenses - Bio-AI Health; Pfizer; Replimune |
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No Relationships to Disclose |
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No Relationships to Disclose |
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Employment - Kartos Therapeutics |
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Leadership - Iovance Biotherapeutics |
Stock and Other Ownership Interests - Acerta Pharma; Iovance Biotherapeutics; Kartos Therapeutics; Telios |
Patents, Royalties, Other Intellectual Property - Kartos Therapeutics; Quogue IP Holdings; Telios |
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Employment - Daichii Sankyo (I) |
Stock and Other Ownership Interests - daichii sankyo (I) |
Consulting or Advisory Role - ChemoCentryx; Exicure; Immunicum; Immunicum; Kartos Therapeutics; SERVIER |
Research Funding - AGIOS (Inst); Amgen (Inst); Curadev (Inst); Exicure (Inst); INCYTE (Inst); Kartos Therapeutics (Inst); Merck (Inst); Regeneron (Inst); Servier (Inst); xencor (Inst) |