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Oral elacestrant vs standard-of-care in estrogen receptor-positive, HER2-negative (ER+/HER2-) advanced or metastatic breast cancer (mBC) without detectable ESR1 mutation (EMERALD): Subgroup analysis by prior duration of CDK4/6i plus endocrine therapy (ET). |
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Honoraria - AstraZeneca; daichi; Genentech; Genomic Health; Gilead Sciences; Novartis; Pfizer; Puma Biotechnology; Seagen |
Consulting or Advisory Role - AstraZeneca; Daiichi Sankyo/UCB Japan; Lilly; Menarini; Puma Biotechnology; tersera; tersera |
Speakers' Bureau - AstraZeneca/Daiichi Sankyo; Genentech; Genomic Health; Gilead Sciences; Novartis; Pfizer; Puma Biotechnology |
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Consulting or Advisory Role - AstraZeneca; Caris Life Sciences; GE Healthcare; GlaxoSmithKline; Lilly; Menarini; Novartis; Pfizer; Rain Oncology; Sanofi (Inst) |
Speakers' Bureau - AstraZeneca; Daiichi-Sankyo; Lilly; Menarini Group; Novartis; Pfizer; Rain Oncology; Roche |
Research Funding - GE Healthcare (Inst); Menarini Silicon Biosystems (Inst); Merck KGaA (Inst); Novartis (Inst); Pfizer (Inst); Prolynx (Inst) |
Patents, Royalties, Other Intellectual Property - ESR1 & MSI detection techniques (patents) (Inst) |
Travel, Accommodations, Expenses - AstraZeneca; Daiichi-Sankyo; Novartis; Pfizer; Roche |
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Consulting or Advisory Role - Lilly (Inst); Novartis (Inst); Pfizer (Inst); Radius Health (Inst); Radius Health (Inst); Roche (Inst); Roche (Inst) |
Travel, Accommodations, Expenses - Lilly (Inst); Pfizer (Inst); Roche (Inst) |
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Honoraria - AstraZeneca; Celgene; OncoSec |
Consulting or Advisory Role - New Century Health; Paragon healthcare; Welwaze |
(OPTIONAL) Uncompensated Relationships - Roche |
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Marie-Ange Mouret-Reynier |
No Relationships to Disclose |
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Stock and Other Ownership Interests - Daiichi Sankyo (I) |
Research Funding - AstraZeneca (Inst); Boehringer Ingelheim (Inst); Daiichi Sankyo (Inst); GlaxoSmithKline (Inst); Lilly (Inst); MSD (Inst); Novartis (Inst); Pfizer (Inst); Roche (Inst); Sanofi (Inst); Seagan (Inst) |
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No Relationships to Disclose |
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Travel, Accommodations, Expenses - ipsen; Teva |
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Speakers' Bureau - Daiichi Sankyo/Astra Zeneca; Eisai; Merck; Seagen |
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Stock and Other Ownership Interests - agenus; Lipocine; MEI Pharma; MustangBio; TG Therapeutics; Tiziana Life Sciences; Vaxart |
Consulting or Advisory Role - Celcuity |
Research Funding - AstraZeneca |
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No Relationships to Disclose |
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No Relationships to Disclose |
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Research Funding - Daichi Sankyo (Inst); Merck (Inst); Novartis (Inst); Pfizer (Inst); Radius Health (Inst); Tolero Pharmaceuticals (Inst) |
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Honoraria - Novartis Pharmaceuticals UK Ltd. |
Consulting or Advisory Role - Daiichi Sankyo/Astra Zeneca; Novartis Pharmaceuticals UK Ltd.; Sanofi/Aventis |
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Consulting or Advisory Role - AstraZeneca; AstraZeneca; Daiichi Sankyo/Astra Zeneca; Gilead Sciences; Lilly; Novartis; Seagen |
Speakers' Bureau - Novartis |
Research Funding - AstraZeneca (Inst) |
Travel, Accommodations, Expenses - Novartis; Roche |
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Honoraria - Gilead Sciences; Roche; Synthon |
Consulting or Advisory Role - Amcure; Amgen; Boehringer Ingelheim; Deloitte; G1 Therapeutics; Gilead Sciences; Macrogenics; Menarini; Novartis; Novartis; Radius Health; Roche; Servier |
Travel, Accommodations, Expenses - Amgen; MSD Oncology; Pfizer; Roche Belgium |
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Stock and Other Ownership Interests - Leuko (I); MedSIR; Nektar |
Honoraria - AstraZeneca; Celgene; Daiichi Sankyo; Eisai; Lilly; Merck Sharp & Dohme; Novartis; Pfizer; Roche; Samsung |
Consulting or Advisory Role - AstraZeneca; Athenex; Bioasis; Bioinvent; Boehringer Ingelheim; Celgene; Cellestia Biotech; Clovis Oncology; Daiichi Sankyo; Ellipses Pharma; ERYTECH Pharma; Expres2ion Biotechnologies; GEMoaB; Gilead Sciences; GlaxoSmithKline; HiberCell; Leuko; Lilly; Menarini; Merck Sharp & Dohme; Polyphor; Reveal Genomics; Roche; Seagen; SERVIER; Zymeworks |
Research Funding - ARIAD (Inst); Astrazeneca (Inst); Baxalta (Inst); Bayer (Inst); Eisai (Inst); Guardant Health (Inst); Merck Sharp & Dohme (Inst); Pfizer (Inst); Piqur (Inst); Puma Biotechnology (Inst); Queen Mary university of London (Inst); Roche (Inst) |
Patents, Royalties, Other Intellectual Property - Her2 as a predictor of response to dual HER2 blockade in the absence of cytotoxic therapy.Aleix Prat, Antonio Llombart, Javier Cortés.US 2019/ 0338368 A1; Pharmaceutical Combinations of A Pi3k Inhibitor And A Microtubule Destabilizing Agent. Javier Cortés Castán, Alejandro Piris Giménez, Violeta Serra Elizalde. WO 2014/199294 A. |
Travel, Accommodations, Expenses - AstraZeneca; Daiichi Sankyo; Eisai; Gilead Sciences; Novartis; Pfizer; Roche |
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Employment - Menarini Group; Stemline Therapeutics |
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Employment - Stemline Therapeutics |
Leadership - Stemline Therapeutics |
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Consulting or Advisory Role - bioTheranostics; Daiichi Sankyo/Astra Zeneca; Foundation Medicine; Genentech; Genentech/Roche (Inst); Immunomedics; Immunomedics (Inst); Innocrin Pharma (Inst); Merck; Novartis; Novartis (Inst); Pfizer; Pfizer (Inst); Philips Healthcare; Puma Biotechnology; Radius Health; Radius Health (Inst); Sanofi; Spectrum Pharmaceuticals |
Research Funding - AstraZeneca/Daiichi Sankyo (Inst); Genentech (Inst); Immunomedics (Inst); Merck (Inst); Novartis (Inst); Pfizer (Inst); Radius Health (Inst); Sanofi (Inst) |