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Trial START-001: A phase 1/2 study of STAR0602, a first-in-class, selective T cell receptor (TCR)-targeting, bifunctional antibody-fusion molecule, as monotherapy in patients with antigen-rich tumors post checkpoint inhibitor (CPI) treatment. |
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Consulting or Advisory Role - alkermes; Asana Biosciences; AstraZeneca; Bristol-Myers Squibb; Eisai; Iovance Biotherapeutics; Merck; Novartis; OncoSec; Pfizer; Replimune |
Research Funding - Aeglea Biotherapeutics (Inst); Amgen (Inst); Asana Biosciences (Inst); BeiGene (Inst); BioMed Valley Discoveries (Inst); Compugen (Inst); Deciphera (Inst); Lilly (Inst); Marengo Therapeutics (Inst); Merck (Inst); Moderna Therapeutics (Inst); Neon Therapeutics (Inst); Pfizer (Inst); Roche/Genentech (Inst); Rubius Therapeutics (Inst); Sanofi (Inst); Strategia (Inst); Strategia (Inst); Synthekine (Inst); Viralytics (Inst) |
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Employment - Marengo Therapeutics |
Leadership - Marengo Therapeutics |
Stock and Other Ownership Interests - Marengo Therapeutics |
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No Relationships to Disclose |
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No Relationships to Disclose |
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Employment - Marengo Therapeutics |
Leadership - Marengo Therapeutics |
Stock and Other Ownership Interests - Marengo Therapeutics |
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No Relationships to Disclose |
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Employment - Marengo Therapeutics |
Stock and Other Ownership Interests - Marengo Therapeutics |
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Employment - Marengo Therapeutics |
Leadership - Marengo Therapeutics |
Stock and Other Ownership Interests - Marengo Therapeutics |
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Employment - Marengo Therapeutics |
Leadership - Marengo Therapeutics |
Stock and Other Ownership Interests - Marengo Therapeutics |
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Employment - Marengo Therapeutics |
Leadership - Marengo Therapeutics |
Stock and Other Ownership Interests - Marengo Therapeutics |
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Stock and Other Ownership Interests - Centessa Pharmaceuticals; Deka Biosciences; HotSpot Therapeutics; Marengo Therapeutics; Shattuck Labs |
Consulting or Advisory Role - Adagene; AstraZeneca; BiolineRx; Centessa Pharmaceuticals; Clover Biopharmaceuticals; Deka Biosciences; Depth Charge Therapeutics; EISAI; Grey Wolf Therapeutics; Gritstone Bio; Guidepoint Global; HiFiBiO Therapeutics; Hotspot Therapeutics; ImCheck therapeutics; Innate Pharma; Johnson & Johnson/Janssen; Lytix Biopharma; Medicxi; MSD; Neogene Therapeutics; OSE Immunotherapeutics; Pegaone; Pierre Fabre; Redx Pharma; Roche; Sanofi; SERVIER; Shattuck Labs; Sotio; Third Rock Ventures |
Research Funding - Boehringer Ingelheim (Inst); Bristol-Myers Squibb (Inst); MSD (Inst); Transgene (Inst) |
Patents, Royalties, Other Intellectual Property - monoclonal antibodies against CD81 (Stanford University) |
Travel, Accommodations, Expenses - Sotio |
Other Relationship - Elsevier |
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Employment - Ankyra Therapeutics |
Leadership - Ankyra Therapeutics |
Stock and Other Ownership Interests - Immuneering; Replimune |
Honoraria - Society for Immunotherapy of Cancer |
Consulting or Advisory Role - Castle Biosciences; Marengo Therapeutics; Midatech Pharma; Tatum Bioscience; Virogin Biotech |
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Leadership - Treadwell Therapeutics (I) |
Stock and Other Ownership Interests - Agios (I) |
Consulting or Advisory Role - Amgen; Arvinas; AstraZeneca/MedImmune; Daiichi Sankyo/UCB Japan; GlaxoSmithKline; Hookipa Pharma; InterRNA; Janpix; Janssen; Merck; Navire; Oncorus; Relay Therapeutics; Roche; Sanofi; Seagen; Tessa Therapeutics; Voronoi Health Analytics |
Research Funding - Amgen (Inst); Amgen (Inst); Amgen (Inst); Astellas Pharma (Inst); AstraZeneca (Inst); AVID Radiopharmaceuticals (Inst); Bayer (Inst); Boehringer Ingelheim (Inst); Bristol-Myers Squibb (Inst); Genentech/Roche (Inst); GlaxoSmithKline (Inst); Intensity Therapeutics (Inst); Karyopharm Therapeutics (Inst); Merck (Inst); Mirati Therapeutics (Inst); Novartis (Inst); Pfizer (Inst); Shattuck Labs (Inst); Symphogen (Inst) |
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Employment - Marengo Therapeutics |
Leadership - Marengo Therapeutics |
Stock and Other Ownership Interests - Marengo Therapeutics |
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Research Funding - Astellas Medivation (Inst); Bavarian Nordic (Inst); Bristol-Myers Squibb (Inst); EMD Serono (Inst); ImmunityBio (Inst); Incyte (Inst); Janssen Oncology (Inst); Kite, a Gilead company (Inst); Marengo Therapeutics (Inst); Merck (Inst); NextCure (Inst); PDS Biotechnology (Inst); Pfizer (Inst); Precigen (Inst); Syndax (Inst); Syntrix Biosystems (Inst) |
Patents, Royalties, Other Intellectual Property - COMBINATION PDL1 AND TGF-BETA BLOCKADE IN PATIENTS WITH HPV+ MALIGNANCIES Publication number: 20200062849 Abstract: The invention provides a method of inhibiting a malignancy associated with human papilloma virus (HPV) comprising administering to a subje |