The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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STAR-221: A randomized, open-label, multicenter, phase 3 trial of domvanalimab, zimberelimab, and chemotherapy versus nivolumab and chemotherapy in previously untreated, locally advanced, unresectable or metastatic gastric, gastroesophageal junction, and esophageal adenocarcinoma.
 
Samuel J Klempner
Stock and Other Ownership Interests - Nuvalent, Inc.; TP Therapeutics
Consulting or Advisory Role - Amgen; Astellas Pharma; AstraZeneca; Bristol-Myers Squibb; Coherus Biosciences; Daiichi Sankyo/UCB Japan; Exact Sciences; Merck; Mersana; Novartis; Sanofi/Aventis; SERVIER
Research Funding - BeiGene (Inst); Leap Therapeutics (Inst); Silverback Therapeutics (Inst)
Other Relationship - Clinical Care Options; NCCN; Research to Practice
 
Kohei Shitara
Honoraria - Bristol-Myers Squibb; Janssen; Takeda
Consulting or Advisory Role - Abbvie; Amgen; Astellas Pharma; Boehringer Ingelheim; Bristol-Myers Squibb; Daiichi Sankyo; GlaxoSmithKline; Guardant Health; Lilly; MSD; Novartis; Ono Pharmaceutical; Pfizer; Taiho Pharmaceutical; Takeda
Research Funding - Amgen (Inst); Astellas Pharma (Inst); Chugai Pharma (Inst); Daiichi Sankyo (Inst); Eisai (Inst); MSD (Inst); Ono Pharmaceutical (Inst); Taiho Pharmaceutical (Inst)
 
Allan Sison
Employment - Arcus Biosciences
Stock and Other Ownership Interests - Arcus Biosciences
 
Jennifer Scott
Employment - Arcus Biosciences
Stock and Other Ownership Interests - Arcus Biosciences
Travel, Accommodations, Expenses - Arcus Biosciences
 
Dana Wishengrad
Employment - Arcus Biosciences
Stock and Other Ownership Interests - Arcus Biosciences
 
Jack Ronayne
Employment - Arcus Biosciences
Stock and Other Ownership Interests - Arcus Biosciences
 
Joon Rhee
Stock and Other Ownership Interests - Gilead Sciences
Travel, Accommodations, Expenses - Gilead Sciences
 
Siddhartha Mitra
Employment - Arcus Biosciences; Five Prime Therapeutics
Stock and Other Ownership Interests - Arcus Biosciences; Five Prime Therapeutics
Travel, Accommodations, Expenses - Arcus Biosciences
 
Dimitry S. A. Nuyten
Employment - Arcus Biosciences; Chinook Therapeutics; Leapfrog Bio; Nektar; Olema Pharmaceuticals (I); Turning Point Therapeutics (I)
Leadership - Arcus Biosciences; Nektar; Olema Pharmaceuticals (I)
Stock and Other Ownership Interests - Abbott Laboratories; Allogene Therapeutics; Amgen; Arcus Biosciences; AstraZeneca; BeiGene; Biomarin; Bristol-Myers Squibb/Celgene; Chinook Therapeutics; Fate Therapeutics; Genmab; Johnson & Johnson/Janssen; Kezar Life Sciences; Merck; Merck; Moderna Therapeutics; Nektar; Novo Nordisk; Pfizer; Pyxis; Radius Health; Roche; Sangamo Therapeutics; Seagen; Synlogic; Synlogic; Teva; Turning Point Therapeutics (I); United Health Group; Viatris
Consulting or Advisory Role - Chinook Therapeutics; Leapfrog Bio
Patents, Royalties, Other Intellectual Property - See https://patents.justia.com/inventor/dimitry-serge-antoine-nuyten
 
Yelena Y. Janjigian
Stock and Other Ownership Interests - Rgenix
Consulting or Advisory Role - AmerisourceBergen; Arcus Biosciences; AskGene Pharma; AstraZeneca; Basilea Pharmaceutical; Bayer; Bristol-Myers Squibb; Daiichi Sankyo; Geneos; GlaxoSmithKline; Imedex; Imugene; Lilly; Lynx Health; Merck; Merck Serono; Mersana; Michael J. Hennessy Associates; Paradigm; Peerview; Pfizer; Phanes Therapeutics; Research to Practice; Rgenix; Seagen; Silverback Therapeutics; Zymeworks
Research Funding - Bayer (Inst); Bristol-Myers Squibb (Inst); Cycle for Survival (Inst); Department of Defense (Inst); Fred's Team (Inst); Genentech/Roche (Inst); Lilly (Inst); Merck (Inst); NCI (Inst); Rgenix (Inst)
Travel, Accommodations, Expenses - Bristol-Myers Squibb Japan
Other Relationship - Axis Medical Education; Clinical Care Options; Research to Practice
 
Zev A. Wainberg
Consulting or Advisory Role - Amgen; Arcus Biosciences; AstraZeneca/MedImmune; Bayer; Bristol-Myers Squibb; Daiichi Sankyo/Astra Zeneca; Ipsen; Lilly; Merck; Merck KGaA; Novartis; Pfizer; PureTech; QED Therapeutics; Seagen
Research Funding - Five Prime Therapeutics (Inst); Merck (Inst); Novartis (Inst); Pfizer (Inst); Plexxikon (Inst)
Travel, Accommodations, Expenses - Bayer; Lilly; Merck