The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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ESR1 mutational landscape and impact of co-existing resistance variants on clinical outcomes in patients with metastatic breast cancer.
 
Arielle J Medford
Honoraria - Natera
Consulting or Advisory Role - Illumina; Natera
 
Ignaty Leshchiner
Leadership - Ennov1
Stock and Other Ownership Interests - Ennov1
Consulting or Advisory Role - Ennov1; Kojin Therapeutics (I); PACT Pharma
 
Justin Cha
No Relationships to Disclose
 
Lesli Ann Kiedrowski
Employment - Guardant Health
Stock and Other Ownership Interests - Guardant Health
 
Andrzej Niemierko
No Relationships to Disclose
 
Jennifer C. Keenan
No Relationships to Disclose
 
Seth Andrew Wander
Consulting or Advisory Role - Biovica; Foundation Medicine; Hologic; Lilly; Pfizer; Puma Biotechnology; Veracyte
Speakers' Bureau - Guardant Health; Lilly
Research Funding - Genentech; Lilly; Nuvation Bio; Pfizer; Regor Therapeutics
 
Laura Spring
Consulting or Advisory Role - AstraZeneca; Daiichi Pharma; G1 Therapeutics; Novartis; Puma Biotechnology
Research Funding - Genentech/Roche; Gilead Sciences; Lilly; Merck (Inst); Philips Healthcare (Inst)
 
Neelima Vidula
Consulting or Advisory Role - AADi; Gilead Sciences; OncoSec; Tersera
Research Funding - DAEHWA Pharmaceutical (Inst); Merck (Inst); Novartis (Inst); Pfizer (Inst); Radius Health (Inst)
 
Charles Sichao Dai
No Relationships to Disclose
 
Steven J. Isakoff
Employment - Merus (I)
Stock and Other Ownership Interests - Merus NV (I)
Consulting or Advisory Role - Paxman
Research Funding - Abbvie (Inst); AstraZeneca/MedImmune (Inst); Genentech (Inst); Merck (Inst); OncoPep (Inst); Outcomes4Me (Inst)
 
Lorenzo Gerratana
Consulting or Advisory Role - AstraZeneca; GlaxoSmithKline; Incyte; Lilly; Novartis
Research Funding - AstraZeneca (Inst)
 
Ami N. Shah
Consulting or Advisory Role - AstraZeneca/MedImmune; AstraZeneca/MedImmune; Gilead Sciences
 
Andrew A. Davis
Consulting or Advisory Role - bioTheranostics; Pfizer
 
Massimo Cristofanilli
Honoraria - Pfizer
Consulting or Advisory Role - AstraZeneca/Daiichi Sankyo; Celcuity; Lilly; Menarini; Olaris; Sermonix Pharmaceuticals; Syantra
Research Funding - Angle; AstraZeneca; Lilly; Menarini Silicon Biosystems; Merck
 
Beverly Moy
Consulting or Advisory Role - HRA Pharma
 
Leif W. Ellisen
Consulting or Advisory Role - Gilead Sciences; KisoJi Biotechnology; mersana
 
Gad Getz
Stock and Other Ownership Interests - Scorpion Therapeutics
Honoraria - MD Anderson Cancer Center; Society for Neuro-Oncology; Society of Tumor Oncology
Consulting or Advisory Role - Scorpion Therapeutics
Research Funding - IBM (Inst); Leidos Biomedical Research/NCI (Inst); Pharmacyclics (Inst)
Patents, Royalties, Other Intellectual Property - Patent related to MSIdetect (Inst); Patent related to MSIdetect (Inst); Patents related to bioinformatic tools (Inst); Royalties from licensing tools
 
Aditya Bardia
Consulting or Advisory Role - bioTheranostics; Daiichi Sankyo/Astra Zeneca; Foundation Medicine; Genentech; Genentech/Roche (Inst); Immunomedics; Immunomedics (Inst); Innocrin Pharma (Inst); Merck; Novartis; Novartis (Inst); Pfizer; Pfizer (Inst); Philips Healthcare; Puma Biotechnology; Radius Health; Radius Health (Inst); Sanofi; Spectrum Pharmaceuticals
Research Funding - AstraZeneca/Daiichi Sankyo (Inst); Genentech (Inst); Immunomedics (Inst); Merck (Inst); Novartis (Inst); Pfizer (Inst); Radius Health (Inst); Sanofi (Inst)