The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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AFNT-211: An FAS-41BB–enhanced TCR-T cell therapy with stem-like properties targeting KRAS G12V-expressing solid tumors.

Michele  Hoffmann

Employment - Affini-T Therapeutics; GlycoEra (I); SaponiQx (I); Umoja Biopharma

Stock and Other Ownership Interests  - Affini-T Therapeutics; GlycoEra (I); SaponiQx (I); Umoja Biopharma

Consulting or Advisory Role - SaponiQx (I)

Patents, Royalties, Other Intellectual Property - Mayo Clinic/Kaiser Permanente (I)

Travel, Accommodations, Expenses - Affini-T Therapeutics; GlycoEra (I); SaponiQx (I); Umoja Biopharma

Lauren  Brown

Employment - Affini-T Therapeutics; Bristol-Myers Squibb

Stock and Other Ownership Interests  - Affini-T Therapeutics; Bristol-Myers Squibb

Research Funding - Affini-T Therapeutics

Patents, Royalties, Other Intellectual Property - Genentech

Travel, Accommodations, Expenses - Affini-T Therapeutics

Other Relationship - Bristol-Myers Squibb

Martin  Campbell

Employment - Affini-T Therapeutics

Klaus  Pechhold

Employment - Affini-T Therapeutics

Xingyue  He

Employment - Affini-T Therapeutics

Stock and Other Ownership Interests  - Affini-T Therapeutics

Patents, Royalties, Other Intellectual Property - Affini-T Therapeutics; Takeda

Travel, Accommodations, Expenses - Affini-T Therapeutics; Takeda

Joseph  Lee

Employment - Affini-T Therapeutics

Stock and Other Ownership Interests  - Affini-T Therapeutics (Inst)

Hongjing  Qu

Employment - Affini-T Therapeutics

Stock and Other Ownership Interests  - Affini-T Therapeutics

Patents, Royalties, Other Intellectual Property - Affini-T Therapeutics

Jinsheng  Liang

Employment - Affini-T Therapeutics

Stock and Other Ownership Interests  - Affini-T Therapeutics

Travel, Accommodations, Expenses - Affini-T Therapeutics

Aude  Chapuis

Stock and Other Ownership Interests  - Affini-T Therapeutics; Metagenomi; SignalOne Bio; TScan Therapeutics

Honoraria - Affini-T Therapeutics; BioNTech; SignalOne Bio; TScan Therapeutics

Research Funding - Affini-T Therapeutics; Amazon; Juno Therapeutics; Lonza; SignalOne Bio

Patents, Royalties, Other Intellectual Property - Affini-T Therapeutics; Amazon; Lonza; SignalOne Bio

Philip D  Greenberg

Stock and Other Ownership Interests  - Affini-T Therapeutics; Catalio; Earli; Elpiscience; Fibrogen; ImmunoSCAPE; Metagenomi; Nextech Invest; RAPT Therapeutics

Consulting or Advisory Role - Affini-T Therapeutics; Catalio; Earli; Elpiscience; FibroGen; FLX Bio; ImmunoSCAPE; Juno Therapeutics; Metagenomi; Nextech Invest; RAPT Therapeutics

Research Funding - Affini-T Therapeutics; Juno Therapeutics; Lonza

Patents, Royalties, Other Intellectual Property - Adaptive Biotechnologies; Affini-T Therapeutics; Juno Therapeutics has licensed technology on T cell therapy originating from my laboratory; Lonza

Travel, Accommodations, Expenses - Elpiscience; FLX Bio; Nextech Invest; RAPT Therapeutics

Dirk  Nagorsen

Employment - Amgen

Leadership - Amgen; Amgen

Stock and Other Ownership Interests  - Amgen

Patents, Royalties, Other Intellectual Property - Inventor on patents related to the use of CD3 bispecifics

Markus P  Vallaster

Employment - Affini-T Therapeutics; Obsidian Therapeutics

Stock and Other Ownership Interests  - Affini-T Therapeutics; Obsidian Therapeutics

Martina  Canestraro

Employment - 2seventy bio; Affini-T Therapeutics; Bluebird Bio

Stock and Other Ownership Interests  - 2seventy bio; Affini-T Therapeutics; Bluebird Bio

Research Funding - Affini-T Therapeutics

Patents, Royalties, Other Intellectual Property - Immunocore

Travel, Accommodations, Expenses - 2seventy bio

Other Relationship - 2seventy bio

Hubert  Lam

Employment - Affini-T Therapeutics; Genocea Biosciences

Stock and Other Ownership Interests  - Affini-T Therapeutics; Genocea Biosciences

Research Funding - Affini-T Therapeutics

Patents, Royalties, Other Intellectual Property - Genocea Biosciences

Travel, Accommodations, Expenses - Affini-T Therapeutics

Gary  Shapiro

Employment - Affini-T Therapeutics

Stock and Other Ownership Interests  - Affini-T Therapeutics

Patents, Royalties, Other Intellectual Property - Affini-T Therapeutics

Other Relationship - Takeda

Damien  Hallet

Employment - Affini-T Therapeutics

Stock and Other Ownership Interests  - Affini-T Therapeutics

Kim  Nguyen

Employment - Affini-T Therapeutics; Precision BioSciences

Leadership - Affini-T Therapeutics

Stock and Other Ownership Interests  - Affini-T Therapeutics; Precision BioSciences

Research Funding - Affini-T Therapeutics; Precision BioSciences

Patents, Royalties, Other Intellectual Property - TERUMO

Loic  Vincent

Employment - Affini-T Therapeutics

Stock and Other Ownership Interests  - Affini-T Therapeutics

Consulting or Advisory Role - Alphasights; Bit.Bio; Guidepoint Inc; Kurma Partners

Thomas  Schmitt

Stock and Other Ownership Interests  - Affini-T Therapeutics; SignalOne Bio

Consulting or Advisory Role - Affini-T Therapeutics

Research Funding - Affini-T Therapeutics; Cullinan Oncology; Lonza; SignalOne Bio

Patents, Royalties, Other Intellectual Property - Affini-T Therapeutics; Lonza