The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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Tissue and plasma-based mechanisms of resistance to first-line osimertinib in EGFR-mutant NSCLC: A multi-institutional cohort.
 
Zofia Piotrowska
Consulting or Advisory Role - AstraZeneca; C4 Therapeutics; Cullinan Oncology; Daiichi Sankyo Europe GmbH; Janssen; Lilly; Taiho Pharmaceutical; Takeda
Research Funding - Abbvie (Inst); ARIAD/Takeda (Inst); AstraZeneca (Inst); Blueprint Medicines (Inst); Cullinan Oncology (Inst); Daiichi Sankyo Europe GmbH (Inst); GlaxoSmithKline/Tesaro (Inst); GlaxoSmithKline/Tesaro (Inst); Janssen Oncology (Inst); Novartis (Inst); Spectrum Pharmaceuticals (Inst)
(OPTIONAL) Uncompensated Relationships - AstraZeneca/MedImmune
 
Lanyi Nora Chen
No Relationships to Disclose
 
Elaine Shum
Consulting or Advisory Role - AstraZeneca; Blueprint Medicines; Boehringer Ingelheim; Genentech; Janssen
Research Funding - Delfi Diagnostics (Inst)
Travel, Accommodations, Expenses - AstraZeneca; Boehringer Ingelheim; Nektar
 
Cathleen Park
No Relationships to Disclose
 
Matthew Guo
No Relationships to Disclose
 
Ying Liu
No Relationships to Disclose
 
Misha Tran
No Relationships to Disclose
 
Jennifer Aline Marks
Honoraria - Curio Science
Consulting or Advisory Role - Targeted Healthcare Communications
Travel, Accommodations, Expenses - IDEOlogy Health
 
Mandeep Banwait
No Relationships to Disclose
 
Stephen V. Liu
Consulting or Advisory Role - AstraZeneca; Bristol-Myers Squibb; Candel Therapeutics; Catalyst Pharmaceuticals; Daiichi Sankyo/UCB Japan; Eisai; Elevation Oncology; Genentech; Gilead Sciences; Guardant Health; Janssen Oncology; Jazz Pharmaceuticals; Merus; MSD Oncology; Novartis; Regeneron; Sanofi; Takeda; Turning Point Therapeutics
Research Funding - Alkermes (Inst); Elevation Oncology (Inst); Genentech/Roche (Inst); Gilead Sciences (Inst); Merck (Inst); Merus (Inst); Nuvalent, Inc. (Inst); RAPT Therapeutics (Inst); Turning Point Therapeutics (Inst)
Travel, Accommodations, Expenses - Caris Life Sciences
 
Susan Combs Scott
Consulting or Advisory Role - Foundation Medicine; Genentech; Regeneron
 
Christine M. Bestvina
Consulting or Advisory Role - Abbvie (I); AstraZeneca; Bristol-Myers Squibb/Celgene; Creative Educational Concepts; Curio Science; CVS; Genentech; Janssen; Jazz Pharmaceuticals; Novartis; Novocure; OncLive Clinical Congress Consultants; Sanofi/Regeneron; Seagen; Takeda
Speakers' Bureau - Merck
Research Funding - AstraZeneca/MedImmune; Bristol-Myers Squibb
 
Jonathan W. Riess
Consulting or Advisory Role - Bayer; BeiGene; Biodesix; Blueprint Medicines; Boehringer Ingelheim; Bristol-Myers Squibb/Celgene; Daiichi Sankyo; EMD Serono; Genentech; Janssen Oncology; Jazz Pharmaceuticals; Merus NV; Novartis; Regeneron; Sanofi; Seagen; Summit pharmaceuticals; Turning Point Therapeutics
Research Funding - ArriVent Biopharma (Inst); AstraZeneca/MedImmune (Inst); Boehringer Ingelheim (Inst); Calithera Biosciences (Inst); Merck (Inst); Novartis (Inst); Revolution Medicines (Inst); Spectrum Pharmaceuticals (Inst)
Travel, Accommodations, Expenses - AstraZeneca
 
Kristen A. Marrone
Honoraria - AstraZeneca
Consulting or Advisory Role - Amgen; AstraZeneca; Daiichi Sankyo/Lilly; Janssen; Mirati Therapeutics; Puma Biotechnology; Regeneron
Research Funding - AstraZeneca (Inst); Bristol-Myers Squibb (Inst); Mirati Therapeutics
 
Richard Delmar Hall
Consulting or Advisory Role - Bristol-Myers Squibb/Ono Pharmaceutical; Jazz Pharmaceuticals; OncoCyte
Research Funding - AstraZeneca/MedImmune (Inst); Daiichi Sankyo/Lilly (Inst); Genentech; Lilly (Inst); Merck Sharp & Dohme (Inst); Mirati Therapeutics (Inst)
 
Ryan D. Gentzler
Honoraria - OncLive; Targeted Oncology
Consulting or Advisory Role - AstraZeneca; Daiichi Sankyo/Astra Zeneca; Gilead Sciences; Janssen; Jazz Pharmaceuticals; Mirati Therapeutics; OncoCyte; Sanofi; Takeda
Research Funding - Amgen (Inst); AstraZeneca (Inst); Bristol-Myers Squibb (Inst); Bristol-Myers Squibb (Inst); Daiichi Sankyo (Inst); Helsinn Therapeutics (Inst); Janssen (Inst); Jounce Therapeutics (Inst); Merck (Inst); Mirati Therapeutics (Inst); Pfizer (Inst); RTI International (Inst); Takeda (Inst)
 
Catherine A. Shu
Consulting or Advisory Role - Arcus Biosciences; AstraZeneca; Genentech/Roche; Janssen; Mirati Therapeutics; Takeda
Research Funding - AstraZeneca (Inst); Genentech/Roche (Inst); Janssen (Inst)