The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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The SPEARHEAD-1 trial of afamitresgene autoleucel (afami-cel [formerly ADP-A2M4]): Pooled analysis of cytokine release syndrome across cohorts in patients with advanced synovial sarcoma.
 
Sandra P. D'Angelo
Honoraria - Adaptimmune; GlaxoSmithKline; Pfizer; Rain Therapeutics; SERVIER
Consulting or Advisory Role - Adaptimmune; GlaxoSmithKline; Nektar; Pfizer; Rain Therapeutics; Rain Therapeutics; Servier
 
Kristen N. Ganjoo
Consulting or Advisory Role - Deciphera; Foundation Medicine
 
Jean-Yves Blay
Leadership - Innate Pharma
Honoraria - AstraZeneca; Bayer; BMS; Deciphera; Ignyta; MSD; PharmaMar; Roche
Consulting or Advisory Role - Bayer; Blueprint Medicines; Deciphera; Deciphera; Deciphera; Deciphera; Karyopharm Therapeutics; Pharmamar; Roche
Research Funding - AstraZeneca (Inst); Bayer (Inst); BMS (Inst); DEciphera (Inst); GlaxoSmithKline (Inst); MSD (Inst); Novartis (Inst); OSE Pharma (Inst); Pharmamar (Inst); Roche (Inst)
Travel, Accommodations, Expenses - Roche
 
Claudia Valverde
Consulting or Advisory Role - Bayer; Boehringer Ingelheim; Deciphera; PharmaMar
Research Funding - Bayer; Boehringer Ingelheim; Deciphera; Novartis; PharmaMar; Philogen
Travel, Accommodations, Expenses - Boehringer Ingelheim; PharmaMar
 
Dejka M. Araujo
Research Funding - Adaptimmune (Inst); GlaxoSmithKline (Inst); Immatics (Inst)
 
Albiruni Ryan Abdul Razak
Consulting or Advisory Role - Adaptimmune; Bayer; GlaxoSmithKline; Inhibrx; Medison
Research Funding - 23 and Me; Abbvie; Adaptimmune; Amgen; Blueprint Medicines; Boehringer Ingelheim; Bristol-Myers Squibb; Daiichi Sankyo; Deciphera; Frontier Therapeutics; GlaxoSmithKline; Iterion Therapeutics; Karyopharm Therapeutics; MedImmune; Merck; Neoleukin Therapeutics; Pfizer; Rain Therapeutics; Roche/Genentech; Symphogen
Expert Testimony - Medison
 
Axel Le Cesne
Honoraria - Bayer; Deciphera; PharmaMar
 
Scott Schuetze
Consulting or Advisory Role - Adaptimmune; Boehringer Ingelheim
Research Funding - Adaptimmune (Inst); Amgen (Inst); Blueprint Medicines (Inst); GlaxoSmithKline (Inst); Karyopharm Therapeutics (Inst); Rain Therapeutics (Inst); TRACON Pharma (Inst)
 
Michael J Wagner
Consulting or Advisory Role - AADi; Adaptimmune; Deciphera; Epizyme
Research Funding - Adaptimmune (Inst); Athenex (Inst); Deciphera (Inst); Foghorn Therapeutics (Inst); GlaxoSmithKline (Inst); Incyte (Inst); Lilly (Inst); Presage Biosciences (Inst)
Travel, Accommodations, Expenses - Epizyme
 
Steven Attia
Research Funding - AB Science (Inst); Adaptimmune (Inst); Advenchen Laboratories (Inst); Ayala Pharmaceuticals (Inst); Bavarian Nordic (Inst); Bayer (Inst); Blueprint Medicines (Inst); Boehringer Ingelheim (Inst); BTG (Inst); C4 Therapeutics (Inst); CBA Pharma (Inst); Deciphera (Inst); Desmoid Tumor Research Foundation; Epizyme (Inst); FORMA Therapeutics (Inst); Genmab (Inst); GlaxoSmithKline (Inst); Gradalis (Inst); Incyte (Inst); InhibRx (Inst); Karyopharm Therapeutics (Inst); Lilly (Inst); Merck (Inst); Monopar Therapeutics (Inst); Novartis (Inst); Noxopharm (Inst); Philogen (Inst); PTC Therapeutics (Inst); Rain Therapeutics (Inst); Salarius Pharmaceuticals (Inst); SpringWorks Therapeutics (Inst); Takeda (Inst); Theseus Pharmaceuticals (Inst); TRACON Pharma (Inst); TRACON Pharma (Inst); Trillium Therapeutics (Inst)
 
Edouard Forcade
Speakers' Bureau - Alexion Pharmaceuticals; Astellas Pharma; Gilead Sciences; GlaxoSmithKline; Novartis; Sanofi
Travel, Accommodations, Expenses - Alexion Pharmaceuticals; Gilead Sciences; Sanofi
 
Mihaela Druta
Consulting or Advisory Role - AADi; Adaptimmune; Decipher Biosciences
Speakers' Bureau - AADi; Deciphera
Travel, Accommodations, Expenses - AADi
 
Seth Pollack
Consulting or Advisory Role - AADi; Apexigen; Bayer; Daichii Sankyo; Deciphera; Epizyme; GlaxoSmithKline; Obsidian Therapeutics; Sensei Biotherapeutics; T-Knife
Speakers' Bureau - Deciphera
Research Funding - Obsidian Therapeutics (Inst)
 
Jane Bai
Employment - Adaptimmune
Stock and Other Ownership Interests - Adaptimmune
 
Colin Lunt
Employment - Adaptimmune
Stock and Other Ownership Interests - Adaptimmune
 
Amy Sun
Employment - Adaptimmune
Stock and Other Ownership Interests - Adaptimmune
 
Murray Yule
Employment - Adaptimmune
Stock and Other Ownership Interests - Adaptimmune
 
Cheryl McAlpine
Employment - Adaptimmune
Stock and Other Ownership Interests - Adaptimmune
 
Dennis Williams
Employment - Adaptimmune
Stock and Other Ownership Interests - Adaptimmune
 
Brian Andrew Van Tine
Leadership - Polaris
Honoraria - Bionest Partner; Horizon CME; Research to Practice; Targeted Oncology
Consulting or Advisory Role - Adaptimmune; ADRx; Apexigen; Ayala Pharmaceuticals; Bayer; Boehringer Ingelheim; Cytokinetics; Daiihi Sankyo; Deciphera; EcoR1 Capital; EcoR1 Capital; EMD Serono; Epizyme; GlaxoSmithKline; Immune Design; Intellisphere; Lilly; Novartis; Pfizer; PTC Therapeutics
Speakers' Bureau - Adaptimmune; GlaxoSmithKline; Lilly; Novartis
Research Funding - GlaxoSmithKline; Merck; Pfizer; TRACON Pharma
Patents, Royalties, Other Intellectual Property - Accuronix Therapeutics- Licensing agreement. Sigma-2 Receptor Ligands and Therapeutic uses therefor (006766), • Modular Platform for Targeted Therapeutic Delivery (006755), • Sigma-2 Receptor Ligand Drug Conjugates as Antitumor Compounds, Methods of synth; Patent on ALEXT3102; Patent on the use of ME1 as a biomarker
Expert Testimony - Health Advances
Travel, Accommodations, Expenses - Adaptimmune; Advenchen Laboratories; GlaxoSmithKline; Lilly