The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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Safety and efficacy of Sleeping Beauty TCR-T cells targeting shared KRAS and TP53 mutations expressed by solid tumors in first-in-human phase 1 study.
 
Maria Pia Morelli
No Relationships to Disclose
 
Marcelo Vailati Negrao
Consulting or Advisory Role - Genentech; Merck; Mirati Therapeutics; Novartis
Research Funding - Alaunos Therapeutics (Inst); AstraZeneca (Inst); Checkmate Pharmaceuticals (Inst); Genentech (Inst); Mirati Therapeutics (Inst); Novartis (Inst); Pfizer (Inst)
Other Relationship - Apothecom; Ashfield Healthcare; ZIOPHARM Oncology
 
Matthew R. Collinson-Pautz
Employment - Alaunos Therapeutics; Envision Healthcare (I)
Stock and Other Ownership Interests - Alaunos Therapeutics; Bellicum Pharmaceuticals
Patents, Royalties, Other Intellectual Property - Inventorship on patent applications related to methods and discovery neoantigen-specific T cell receptors and TCR-T cell technologies.; Inventorship on patents and/or patent applications relating to CAR-T technologies and molecular switches to modulate cell states.
 
Kamisha Jernigan
No Relationships to Disclose
 
Nathan A. Demars
Employment - Alaunos Therapeutics; Neogene Therapeutics
Stock and Other Ownership Interests - Abbvie; Alaunos Therapeutics; Verastem
Patents, Royalties, Other Intellectual Property - Alaunos patents
Travel, Accommodations, Expenses - Alaunos Therapeutics
 
Aaron Weitzman
Employment - Abbvie; Amgen; inseption; Quadriga Biosciences; Tango Therapeutics
Leadership - Tango Therapeutics
Stock and Other Ownership Interests - Apros Therapeutics; Immune-Onc Therapeutics; Quadriga Biosciences; Tango Therapeutics
Consulting or Advisory Role - Alaunos Therapeutics; Apexigen; biosion; Frontier Medicines; hillstream; Kuur Therapeutics; lumeda; mainline; Sensei Biotherapeutics; Surface Oncology; Tango Therapeutics; Xinthera
Travel, Accommodations, Expenses - Tango Therapeutics
 
Frances Adeyemi
No Relationships to Disclose
 
Victor H Carpio
Employment - Alaunos Therapeutics
 
Amir A. Jazaeri
Stock and Other Ownership Interests - Avenge Bio; Greenfire Bio
Honoraria - Gerson Lehrman Group; Guidepoint Global
Consulting or Advisory Role - Adicet Bio; Alkermes; Macrogenics; NuProbe; Theolytics
Research Funding - Aravive (Inst); AstraZeneca (Inst); Avenge Bio (Inst); Bristol-Myers Squibb (Inst); immatics (Inst); Iovance Biotherapeutics (Inst); Lilly (Inst); Macrogenics (Inst); Merck (Inst); Pfizer (Inst); Xencor (Inst)
 
Benny Johnson
Consulting or Advisory Role - Gritstone Bio; Incyte; Insmed; Pfizer; Taiho Oncology
Research Funding - Bristol-Myers Squibb (Inst); Gateway Foundation (Inst); Syntrix Biosystems (Inst)
 
Shubham Pant
Consulting or Advisory Role - Ipsen; Janssen; Novartis; Zymeworks
Research Funding - 4D Pharma (Inst); Arcus Biosciences (Inst); Astellas Pharma (Inst); bionte (Inst); Boehringer Ingelheim (Inst); Bristol-Myers Squibb (Inst); Elicio Therapeutics (Inst); Ipsen (Inst); Janssen (Inst); Lilly (Inst); Mirati Therapeutics (Inst); NGM Biopharmaceuticals (Inst); Novartis (Inst); Pfizer (Inst); Purple Biotech (Inst); Rgenix (Inst); Xencor (Inst); Zymeworks (Inst)
 
Partow Kebriaei
Honoraria - Kite, a Gilead company; Pfizer
Consulting or Advisory Role - Jazz Pharmaceuticals
Travel, Accommodations, Expenses - Kite, a Gilead company; Pfizer
 
Abhishek K Srivastava
Employment - Alaunos Therapeutics
Leadership - Alaunos Therapeutics
Stock and Other Ownership Interests - Alaunos Therapeutics
 
Drew Caldwell Deniger
Employment - Alaunos Therapeutics
Leadership - Alaunos Therapeutics
Stock and Other Ownership Interests - Alaunos Therapeutics
Research Funding - Alaunos Therapeutics
Patents, Royalties, Other Intellectual Property - Alaunos Therapeutics; National Cancer Institute
 
John Heymach
Consulting or Advisory Role - AstraZeneca; BerGenBio; Boehringer Ingelheim; Bristol-Myers Squibb; DAVA Pharmaceuticals; EMD Serono; Genentech/Roche; GlaxoSmithKline; Hengrui Pharmaceutical; Janssen; Jazz Pharmaceuticals; Jazz Pharmaceuticals; Lilly (Inst); Mirati Therapeutics; Nexus Health Systems; Pneuma Respiratory; Regeneron; Sanofi/Aventis; Spectrum Pharmaceuticals; Takeda
Speakers' Bureau - DAVA Pharmaceuticals; IDEOlogy Health; MJH Life Sciences
Research Funding - AstraZeneca (Inst); Boehringer Ingelheim (Inst); Spectrum Pharmaceuticals; Takeda (Inst)
Patents, Royalties, Other Intellectual Property - Licensing agreement between Spectrum and MD Anderson (including myself) regarding intellectual property for treatment of EGFR and HER2 exon 20 mutations
 
Scott Kopetz
Stock and Other Ownership Interests - Frontier Medicines; Iylon; Lutris; Navire; Xilis
Consulting or Advisory Role - Abbvie; Accademia Nazionale Di Medicina (ACCMED); Amal Therapeutics; Amgen; AstraZeneca/MedImmune; Bayer Health; Bicara Therapeutics; Black Diamond Therapeutics; Boehringer Ingelheim; Bristol-Myers Squibb/Medarex; Cardiff Oncology; Carina Biotech; CureTeq; EMD Serono; Endeavor BioMedicines; Flame Biosciences; Foundation Medicine; Frontier Medicines; Genentech; Genomic Health; Gilead Sciences; GlaxoSmithKline; HalioDx; Harbinger Oncology, Inc; Holy Stone Healthcare; Inivata; Ipsen; Iylon; Jacobio; Jazz Pharmaceuticals; Johnson & Johnson/Janssen; Lilly; Lutris; Merck; Mirati Therapeutics; NeoGenomics Laboratories; Novartis; Numab; Ono Pharmaceutical; Pfizer; Redx Pharma; Repare Therapeutics; Replimune; Servier; Taiho Pharmaceutical; Takeda; Tempus; Xilis; Zentalis
Research Funding - Amgen; Array BioPharma; Biocartis; Daiichi Sankyo; EMD Serono; Genentech/Roche; Guardant Health; Lilly; MedImmune; Novartis; Sanofi