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Safety and efficacy of Sleeping Beauty TCR-T cells targeting shared KRAS and TP53 mutations expressed by solid tumors in first-in-human phase 1 study. |
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No Relationships to Disclose |
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Consulting or Advisory Role - Genentech; Merck; Mirati Therapeutics; Novartis |
Research Funding - Alaunos Therapeutics (Inst); AstraZeneca (Inst); Checkmate Pharmaceuticals (Inst); Genentech (Inst); Mirati Therapeutics (Inst); Novartis (Inst); Pfizer (Inst) |
Other Relationship - Apothecom; Ashfield Healthcare; ZIOPHARM Oncology |
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Matthew R. Collinson-Pautz |
Employment - Alaunos Therapeutics; Envision Healthcare (I) |
Stock and Other Ownership Interests - Alaunos Therapeutics; Bellicum Pharmaceuticals |
Patents, Royalties, Other Intellectual Property - Inventorship on patent applications related to methods and discovery neoantigen-specific T cell receptors and TCR-T cell technologies.; Inventorship on patents and/or patent applications relating to CAR-T technologies and molecular switches to modulate cell states. |
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No Relationships to Disclose |
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No Relationships to Disclose |
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Employment - Abbvie; Amgen; inseption; Quadriga Biosciences; Tango Therapeutics |
Leadership - Tango Therapeutics |
Stock and Other Ownership Interests - Apros Therapeutics; Immune-Onc Therapeutics; Quadriga Biosciences; Tango Therapeutics |
Consulting or Advisory Role - Alaunos Therapeutics; Apexigen; biosion; Frontier Medicines; hillstream; Kuur Therapeutics; lumeda; mainline; Sensei Biotherapeutics; Surface Oncology; Tango Therapeutics; Xinthera |
Travel, Accommodations, Expenses - Tango Therapeutics |
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No Relationships to Disclose |
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Employment - Alaunos Therapeutics |
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Stock and Other Ownership Interests - Avenge Bio; Greenfire Bio |
Honoraria - Gerson Lehrman Group; Guidepoint Global |
Consulting or Advisory Role - Adicet Bio; Alkermes; Macrogenics; NuProbe; Theolytics |
Research Funding - Aravive (Inst); AstraZeneca (Inst); Avenge Bio (Inst); Bristol-Myers Squibb (Inst); immatics (Inst); Iovance Biotherapeutics (Inst); Lilly (Inst); Macrogenics (Inst); Merck (Inst); Pfizer (Inst); Xencor (Inst) |
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Consulting or Advisory Role - Gritstone Bio; Incyte; Insmed; Pfizer; Taiho Oncology |
Research Funding - Bristol-Myers Squibb (Inst); Gateway Foundation (Inst); Syntrix Biosystems (Inst) |
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Consulting or Advisory Role - Ipsen; Janssen; Novartis; Zymeworks |
Research Funding - 4D Pharma (Inst); Arcus Biosciences (Inst); Astellas Pharma (Inst); bionte (Inst); Boehringer Ingelheim (Inst); Bristol-Myers Squibb (Inst); Elicio Therapeutics (Inst); Ipsen (Inst); Janssen (Inst); Lilly (Inst); Mirati Therapeutics (Inst); NGM Biopharmaceuticals (Inst); Novartis (Inst); Pfizer (Inst); Purple Biotech (Inst); Rgenix (Inst); Xencor (Inst); Zymeworks (Inst) |
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Honoraria - Kite, a Gilead company; Pfizer |
Consulting or Advisory Role - Jazz Pharmaceuticals |
Travel, Accommodations, Expenses - Kite, a Gilead company; Pfizer |
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Employment - Alaunos Therapeutics |
Leadership - Alaunos Therapeutics |
Stock and Other Ownership Interests - Alaunos Therapeutics |
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Employment - Alaunos Therapeutics |
Leadership - Alaunos Therapeutics |
Stock and Other Ownership Interests - Alaunos Therapeutics |
Research Funding - Alaunos Therapeutics |
Patents, Royalties, Other Intellectual Property - Alaunos Therapeutics; National Cancer Institute |
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Consulting or Advisory Role - AstraZeneca; BerGenBio; Boehringer Ingelheim; Bristol-Myers Squibb; DAVA Pharmaceuticals; EMD Serono; Genentech/Roche; GlaxoSmithKline; Hengrui Pharmaceutical; Janssen; Jazz Pharmaceuticals; Jazz Pharmaceuticals; Lilly (Inst); Mirati Therapeutics; Nexus Health Systems; Pneuma Respiratory; Regeneron; Sanofi/Aventis; Spectrum Pharmaceuticals; Takeda |
Speakers' Bureau - DAVA Pharmaceuticals; IDEOlogy Health; MJH Life Sciences |
Research Funding - AstraZeneca (Inst); Boehringer Ingelheim (Inst); Spectrum Pharmaceuticals; Takeda (Inst) |
Patents, Royalties, Other Intellectual Property - Licensing agreement between Spectrum and MD Anderson (including myself) regarding intellectual property for treatment of EGFR and HER2 exon 20 mutations |
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Stock and Other Ownership Interests - Frontier Medicines; Iylon; Lutris; Navire; Xilis |
Consulting or Advisory Role - Abbvie; Accademia Nazionale Di Medicina (ACCMED); Amal Therapeutics; Amgen; AstraZeneca/MedImmune; Bayer Health; Bicara Therapeutics; Black Diamond Therapeutics; Boehringer Ingelheim; Bristol-Myers Squibb/Medarex; Cardiff Oncology; Carina Biotech; CureTeq; EMD Serono; Endeavor BioMedicines; Flame Biosciences; Foundation Medicine; Frontier Medicines; Genentech; Genomic Health; Gilead Sciences; GlaxoSmithKline; HalioDx; Harbinger Oncology, Inc; Holy Stone Healthcare; Inivata; Ipsen; Iylon; Jacobio; Jazz Pharmaceuticals; Johnson & Johnson/Janssen; Lilly; Lutris; Merck; Mirati Therapeutics; NeoGenomics Laboratories; Novartis; Numab; Ono Pharmaceutical; Pfizer; Redx Pharma; Repare Therapeutics; Replimune; Servier; Taiho Pharmaceutical; Takeda; Tempus; Xilis; Zentalis |
Research Funding - Amgen; Array BioPharma; Biocartis; Daiichi Sankyo; EMD Serono; Genentech/Roche; Guardant Health; Lilly; MedImmune; Novartis; Sanofi |