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A phase 1 study of AGEN2373, a novel CD137 agonist antibody designed to avoid hepatoxicity, in patients with advanced solid tumors. |
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Employment - Texas Oncology |
Stock and Other Ownership Interests - Texas Oncology |
Research Funding - Mary Crowley Research Center, Dallas Texas |
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Employment - Next Oncology |
Leadership - Next Oncology |
Stock and Other Ownership Interests - Pyxis (Inst) |
Consulting or Advisory Role - AbbVie (Inst); Aclaris Therapeutics (Inst); Adagene (Inst); Agenus (Inst); Aro Biotherapeutics (Inst); Asana Biosciences (Inst); Ascentage Pharma (Inst); Aximmune (Inst); Bayer (Inst); BioInvent (Inst); BluPrint Oncology (Inst); Boehringer Ingelheim (Inst); Bright Peak Therapeutics (Inst); Daiichi Sankyo, Inc. (Inst); Deka Biosciences (Inst); Eleven Biotherapeutics (Inst); Elucida Oncology (Inst); EMD Serono (Inst); Gilde Healthcare (Inst); HBM Partners (Inst); HiberCell (Inst); IDEA Pharma (Inst); Ikena Oncology (Inst); Immuneering (Inst); Immunome (Inst); Immunomet (Inst); IMPAC Medical Systems (Inst); Janssen (Inst); Janssen (Inst); Jazz Pharmaceuticals (Inst); Karma Oncology (Inst); Kirilys Therapeutics (Inst); Lengo Therapeutics (Inst); Lilly (Inst); Link Immunotherapeutics (Inst); Mekanistic Therapeutics (Inst); Menarini (Inst); Mersana (Inst); Mirati Therapeutics (Inst); Nanobiotix (Inst); NBE Therapeutics (Inst); Nerviano Medical Sciences (Inst); Novo Nordisk (Inst); Nurix (Inst); Ocellaris Pharma (Inst); Partner Therapeutics (Inst); Pelican Therapeutics (Inst); Pfizer (Inst); Pieris Pharmaceuticals (Inst); Pierre Fabre (Inst); Pyxis (Inst); Qualigen Therapeutics (Inst); Roche (Inst); Ryvu Therapeutics (Inst); Seagen (Inst); Senti Biosciences (Inst); SK Life Sciences (Inst); Sotio (Inst); Spirea (Inst); Sunshine Guojian (Inst); Transcenta (Inst); Transgene (Inst); Trillium Therapeutics (Inst); Verastem (Inst); Vincerx Pharma (Inst); VRise Therapeutics (Inst); Zentalis (Inst); ZielBio (Inst); Zymeworks (Inst) |
Research Funding - AbbVie (Inst); ABL Bio (Inst); Adagene (Inst); ADC Therapeutics (Inst); Agenus (Inst); Aminex (Inst); Amphivena (Inst); Apros Therapeutics (Inst); Arcellx (Inst); ARMO BioSciences (Inst); Arrys Therapeutics (Inst); Artios (Inst); Asana Biosciences (Inst); Ascentage Pharma (Inst); Astex Pharmaceuticals (Inst); Basilea (Inst); Bioinvent (Inst); Birdie (Inst); BJ Bioscience (Inst); Boehringer Ingelheim (Inst); Boston Biomedical (Inst); CStone Pharmaceuticals (Inst); Daiichi Sankyo, Inc. (Inst); Deciphera (Inst); eFFECTOR Therapeutics (Inst); EMD Serono (Inst); Gilead Sciences (Inst); GlaxoSmithKline (Inst); ImmuneOncia (Inst); Inhibrx (Inst); Innate Pharma (Inst); Janssen Research & Development (Inst); K-Group Beta (Inst); Kechow Pharma (Inst); Kiromic (Inst); Merck Sharp & Dohme (Inst); Mersana (Inst); Mirati Therapeutics (Inst); Naturewise (Inst); NBE Therapeutics (Inst); NextCure (Inst); Nitto BioPharma (Inst); Odonate Therapeutics (Inst); ORIC Pharmaceuticals (Inst); Pfizer (Inst); Pieris Pharmaceuticals (Inst); Qilu Puget Sound Biotherapeutics (Inst); Samumed (Inst); Seagen (Inst); Shanghai HaiHe Pharmaceutical (Inst); Spring Bank (Inst); Sunshine Guojian (Inst); Symphogen (Inst); Syndax (Inst); Synthorx (Inst); Takeda (Inst); Tizona Therapeutics, Inc. (Inst); Zymeworks (Inst) |
Expert Testimony - Immunogen |
Travel, Accommodations, Expenses - Sotio (Inst) |
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Consulting or Advisory Role - Alkermes; Amgen (Inst); Astellas Pharma (Inst); AstraZeneca (Inst); Aura Biosciences; Bristol-Myers Squibb/Celgene; Bristol-Myers Squibb/Medarex (Inst); Castle Biosciences; Chimeron Bio; Corvus Pharmaceuticals (Inst); Delcath Systems; Eisai; Genzyme; Hengrui Pharmaceutical; IDEAYA Biosciences; IDEAYA Biosciences (Inst); Immunocore; InxMed; Iovance Biotherapeutics; Merck; Mirati Therapeutics (Inst); Novartis; Novartis (Inst); Oncosec; Pfizer (Inst); Pierre Fabre; Plexxikon (Inst); PureTech; Regeneron; Rgenix; Roche/Genentech (Inst); Roche/Genentech (Inst); Sorrento Therapeutics; TriSalus Life Sciences |
Speakers' Bureau - Bristol-Myers Squibb/Medarex |
Research Funding - Amgen (Inst); Array BioPharma (Inst); Astellas Pharma (Inst); AstraZeneca (Inst); Bayer (Inst); Bellicum Pharmaceuticals (Inst); Bristol-Myers Squibb (Inst); Corvus Pharmaceuticals (Inst); IDEAYA Biosciences (Inst); Immunocore (Inst); Incyte (Inst); Lilly (Inst); Macrogenics (Inst); Merck (Inst); Mirati Therapeutics (Inst); Novartis (Inst); Pfizer (Inst); Plexxikon (Inst); Regeneron (Inst); Roche/Genentech (Inst) |
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Consulting or Advisory Role - AstraZeneca; Eisai; Janssen; Merck; Volastra Therapeutics |
Research Funding - Agenus; Alkermes; Arcus Biosciences; Checkmate Pharmaceuticals; Compugen; Immunocore; Synthekine |
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Honoraria - ABL bio; Agenus; AstraZeneca/MedImmune; Bayer; Bristol-Myers Squibb; EISAI; EMD Serono; Exelixis; Gilead Sciences; Merck; QED Therapeutics; Qurient; Roche/Genentech; Senti Biosciences; SERVIER; Tallac Therapeutics |
Consulting or Advisory Role - ABL Bio; Agenus; AstraZeneca/MedImmune; Bayer; Bristol-Myers Squibb; Eisai; Exelixis; Gilead Sciences; Merck; Pieris Pharmaceuticals; QED Therapeutics; Qurient; Roche; Senti Biosciences; SERVIER; Tallac Therapeutics |
Research Funding - Astex Pharmaceuticals; AstraZeneca; Fulgent Genetics |
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Consulting or Advisory Role - AstraZeneca; Boehringer Ingelheim |
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Consulting or Advisory Role - AstraZeneca; Bayer; BioNTech; Bristol-Myers Squibb; Clinigen Group; ConcertAI; Eisai; Genentech/Roche; Instil Bio; Merck; Novartis; Partner Therapeutics; Sanofi/Regeneron |
Research Funding - Acrotech Biopharma (Inst); Agenus (Inst); Agenus (Inst); Bristol-Myers Squibb (Inst); Clinigen Group (Inst); Genentech/Roche (Inst); InflaRx (Inst); Merck (Inst); OncoSec (Inst); Pfizer (Inst); Sanofi/Regeneron (Inst); Scholar Rock (Inst) |
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Consulting or Advisory Role - Bristol-Myers Squibb; Castle Biosciences; Merck Sharp & Dohme; Sanofi/Regeneron |
Speakers' Bureau - Bristol-Myers Squibb; Castle Biosciences; Merck Sharp & Dohme; Sanofi/Regeneron |
Research Funding - Amgen (Inst); Astellas Pharma (Inst); AstraZeneca/MedImmune (Inst); BioNTech SE (Inst); Boehringer Ingelheim (Inst); Bristol-Myers Squibb (Inst); Castle Biosciences (Inst); Genentech/Roche (Inst); Instil Bio (Inst); Iovance Biotherapeutics (Inst); Merck Sharp & Dohme (Inst); Oncolys BioPharma (Inst); OncoSec (Inst); Replimune (Inst); Seagen (Inst); Toray Industries (Inst) |
Patents, Royalties, Other Intellectual Property - Lighted Polyhedral surgical retractor; Nerve monitoring dissection device |
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Stock and Other Ownership Interests - Moderna Therapeutics |
Honoraria - Bristol-Myers Squibb; EMD Serono; EMD Serono; Genentech/Roche; Incyte; Sanofi/Regeneron; Sanofi/Regeneron |
Consulting or Advisory Role - Bristol Myers Squibb; Bristol-Myers Squibb; EMD Serono; EMD Serono; Exicure; Genentech/Roche; Sanofi/Regeneron; Sanofi/Regeneron; Sanofi/Regeneron (Inst) |
Research Funding - 4SC (Inst); Amphivena (Inst); Bristol-Myers Squibb (Inst); Checkmate Pharmaceuticals (Inst); EMD Serono (Inst); Exicure (Inst); Incyte (Inst); Merck (Inst); NantWorks (Inst); Nektar (Inst); Novartis (Inst); Seven and Eight Biopharmaceuticals (Inst); TriSalus Life Sciences (Inst) |
Travel, Accommodations, Expenses - NantWorks; Sanofi/Regeneron |
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Honoraria - ACM Biolabs; Clinical Care Options (CCO); Gerson Lehrman Group; Medical Learning Group; Merck; Xilio Therapeutics |
Consulting or Advisory Role - Checkmate Pharmaceuticals; Clinical Care Options; Finch Therapeutics; Gerson Lehrman Group; Xilio Therapeutics |
Speakers' Bureau - Castle Biosciences |
Research Funding - Arcus Biosciences; CellSight Technologies; Checkmate Pharmaceuticals; GlaxoSmithKline; Merck; Merck; Zucero Therapeutics (Inst) |
Patents, Royalties, Other Intellectual Property - Application No.: 63/124,231; Enteric Microbiotype Signatures of Immune-related Adverse Events and Response in Relation to Anti-PD-1 Immunotherapy |
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Consulting or Advisory Role - Castle Biosciences; Castle Biosciences; Eisai; Iovance Biotherapeutics; Sapience Therapeutics |
Research Funding - BioNTech (Inst); Bristol-Myers Squibb (Inst); Day One Biopharmaceuticals (Inst); Dragonfly Therapeutics (Inst); Foghorn Therapeutics (Inst); Immunocore (Inst); Instil Bio (Inst); Iovance Biotherapeutics (Inst); Novartis (Inst); Regeneron (Inst); Replimune (Inst); TriSalus Life Sciences (Inst); Ultimovacs (Inst); Vyriad (Inst) |
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Honoraria - Bayer; Blueprint Medicines; Bristol Myers Squibb Foundation; Eisai; Merck; Pfizer; Regeneron; Roche |
Consulting or Advisory Role - Bayer; Blueprint Medicines; Bristol-Myers Squibb; Cascade Prodrug; Eisai; Exelixis; Immune-Onc Therapeutics; Loxo; Merck; Novartis; Pfizer; Regeneron; Sanofi |
Speakers' Bureau - Blueprint Medicines; Bristol-Myers Squibb; Eisai; Merck |
Research Funding - Blueprint Medicines (Inst); Bristol-Myers Squibb (Inst); Eisai (Inst); Loxo/Bayer (Inst); Merck (Inst); Moderna Therapeutics (Inst); Pfizer (Inst); Seagen (Inst) |
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Stock and Other Ownership Interests - Agenus |
Travel, Accommodations, Expenses - Agenus |
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Stock and Other Ownership Interests - Agenus |
Research Funding - Agenus |
Travel, Accommodations, Expenses - Agenus |
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No Relationships to Disclose |
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Stock and Other Ownership Interests - Agenus |
Research Funding - Agenus |
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Research Funding - Agenus |
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Stock and Other Ownership Interests - Agenus |
Research Funding - Agenus |
Travel, Accommodations, Expenses - Agenus |
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Stock and Other Ownership Interests - Agenus |
Research Funding - Agenus |
Travel, Accommodations, Expenses - Agenus |
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Stock and Other Ownership Interests - Agenus |