The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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Results from a first-in-human phase 1B study of a complement factor H inhibitor (GT103) in patients with non-small cell lung cancer (NSCLC).
 
Jeffrey Melson Clarke
Consulting or Advisory Role - Amgen; AstraZeneca; G1 Therapeutics; Genentech; Novartis; Pfizer; Spectrum Pharmaceuticals; Turning Point Therapeutics; Vivacitas Oncology
Speakers' Bureau - AstraZeneca
Research Funding - Abbvie; Achilles Therapeutics; Adaptimmune; Array BioPharma; AstraZeneca; Bristol-Myers Squibb; Cellular Biomedicine Group; Genentech; GlaxoSmithKline; Grid Therapeutics; Moderna Therapeutics; Spectrum Pharmaceuticals
(OPTIONAL) Uncompensated Relationships - Lung Cancer Initiative of North Carolina
 
Tom Stinchcombe
Consulting or Advisory Role - Daiichi Sankyo/Astra Zeneca; Eisai/H3 Biomedicine; G1 Therapeutics; Genentech/Roche; GlaxoSmithKline; Janssen Oncology; Sanofi/Aventis; Spectrum Pharmaceuticals; Takeda; Turning Point Therapeutics
Research Funding - AstraZeneca (Inst); Genentech/Roche (Inst); Mirati Therapeutics (Inst); Seagen (Inst); Takeda (Inst)
 
Lin Gu
No Relationships to Disclose
 
Hirva Mamdani
Consulting or Advisory Role - AstraZeneca; Genentech; MorphoSys (I); Seagen (I); Zentalis
 
Scott Joseph Antonia
Consulting or Advisory Role - Achilles Therapeutics; Amgen; AstraZeneca; Caris Life Sciences; Cellular Biomedicine Group; Celsius Therapeutics; EMD Serono; G1 Therapeutics; GlaxoSmithKline; Glympse Bio; Memgen; Merck; Nektar; RAPT Therapeutics; Samyang; Venn Biosciences Corporation
 
George R. Simon
Consulting or Advisory Role - AstraZeneca; Genprex; Onc.AI; Reflexion Medical
Speakers' Bureau - AstraZeneca; OncLive
 
Guru P. Sonpavde
Employment - Myriad Genetics (I)
Honoraria - UpToDate
Consulting or Advisory Role - Astellas Pharma; Bicycle Therapeutics; Bristol-Myers Squibb; EMD Serono; Exelixis; G1 Therapeutics; Genentech; Gilead Sciences; Infinity Pharmaceuticals; Janssen; Loxo/Lilly; Lucence; Merck; Pfizer; Scholar Rock; Seagen; Syapse; Vial
Speakers' Bureau - Exelixis; Gilead Sciences; INFORMAÇÃO BRASILEIRA DE ONCOLOGIA; Medscape; Natera; Onclive; Physicans' Education Resource; Research to Practice; Seagen
Research Funding - AstraZeneca (Inst); Bristol-Myers Squibb (Inst); EMD Serono (Inst); GeneCentric (Inst); Gilead Sciences (Inst); Jazz Pharmaceuticals (Inst); Predicine (Inst); QED Therapeutics (Inst); Sanofi (Inst)
Travel, Accommodations, Expenses - Bristol-Myers Squibb
Other Relationship - Astellas Pharma; Bristol-Myers Squibb; Elsevier; G1 Therapeutics; Mereo BioPharma; QED Therapeutics
 
Neal E. Ready
Consulting or Advisory Role - Abbvie; AstraZeneca; AstraZeneca; Bristol-Myers Squibb; Celgene; G1 Therapeutics; Jazz Pharmaceuticals; Merck; Merck Serono; Novartis; Pfizer; Regeneron; Sanofi/Regeneron
Speakers' Bureau - Bristol-Myers Squibb; Jazz Pharmaceuticals
Research Funding - Bristol-Myers Squibb; Memgen (Inst); Merck
 
Jeffrey Crawford
Consulting or Advisory Role - Actimed Therapeutics; Amgen; AVEO; BioAtla; Enzychem Lifesciences; Faraday Pharmaceuticals; Fresenius; G1 Therapeutics; LUNGevity Foundation; Merck; National Institute on Aging; Partner Therapeutics; Pfizer; Sandoz; Seagen; Spectrum Pharmaceuticals
Research Funding - AstraZeneca; Helsinn Healthcare; Pfizer
 
Michael Campa
Stock and Other Ownership Interests - Grid Therapeutics
Consulting or Advisory Role - Grid Therapeutics
Patents, Royalties, Other Intellectual Property - I am an inventor on a patent held by Duke that will be licensed by Grid Therapeutics.
 
Elizabeth Gottlin
No Relationships to Disclose
 
Ryan Bushey
No Relationships to Disclose
 
James Emmett Herndon
No Relationships to Disclose
 
Edward Patz
Leadership - Grid Therapeutics
Stock and Other Ownership Interests - Grid Therapeutics