The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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Results of phase I-II bridging study for Nous-209, a neoantigen cancer immunotherapy, in combination with pembrolizumab as first line treatment in patients with advanced dMMR/MSI-h colorectal cancer.
 
Michael J. Overman
Consulting or Advisory Role - 3D Medicines; Array BioPharma; Bristol-Myers Squibb; Eisai; Gritstone Bio; Janssen; Janssen; MedImmune; Merck; Novartis; Pfizer; Pfizer; Promega; Roche/Genentech; Spectrum Pharmaceuticals
Research Funding - Bristol-Myers Squibb; MedImmune; Merck; Roche
 
Joan Maurel
Consulting or Advisory Role - AstraZeneca; Pierre Fabre; Sanofi; Servier; Shire; Sirtex Medical
Research Funding - Amgen; Biocartis; Biocartis; Incyte; Merck Serono; NanoString Technologies; Roche
Travel, Accommodations, Expenses - Amgen
Other Relationship - Advance Medical/Teladoc Health; AstraZeneca; Bayer; Cancer Expert Now; Fundación Clínica Universitaria; Pierre Fabre; Roche; Sanofi Pasteur; SERVIER; Shire; Sirtex Medical
 
Paul Eliezer Oberstein
Consulting or Advisory Role - Amal Therapeutics; Aravive; AstraZeneca; AstraZeneca; Merck; QED Therapeutics; Rubius Therapeutics
Speakers' Bureau - AstraZeneca
Research Funding - Amal Therapeutics (Inst); Arcus Biosciences (Inst); Merck (Inst); Novartis (Inst); Rafael Pharmaceuticals (Inst); Roche/Genentech (Inst); Zai Lab (Inst)
Expert Testimony - Ipsen
Travel, Accommodations, Expenses - Merck
 
Susana Roselló-Keränen
Consulting or Advisory Role - SERVIER
Speakers' Bureau - SERVIER
Research Funding - Ability Pharma (Inst); Hutchison MediPharma (Inst); Menarini (Inst); Mirati Therapeutics (Inst); Novartis (Inst); Pfizer (Inst); Pierre Fabre (Inst)
 
Dung T. Le
Honoraria - Merck
Consulting or Advisory Role - Bristol-Myers Squibb; HalioDX; Janssen; Merck; Merus NV; Nouscom
Research Funding - Abbvie (Inst); Aduro Biotech; Bristol-Myers Squibb; Curegenix; Medivir; Merck; Nouscom (Inst)
Patents, Royalties, Other Intellectual Property - Inventor of technology, "Microsatellite Instability as a Pharmacogenomic Marker of Therapeutic Response to Immune Checkpoint Inhibition".
 
Katrina Sophia Pedersen
Consulting or Advisory Role - Array BioPharma; AstraZeneca; Bayer; GlaxoSmithKline; Novartis; Pfizer; SAGA Diagnostics; Taiho Oncology
Speakers' Bureau - Clinical Care Options; WebMD
Research Funding - Abbvie (Inst); Arcus Biosciences (Inst); Boston Biomedical (Inst); Bristol-Myers Squibb (Inst); Cardiff Oncology (Inst); Daiichi Sankyo/Lilly (Inst); HCW Biologics (Inst); Incyte (Inst); Ipsen (Inst); Merck (Inst); Natera (Inst); Nouscom (Inst); Novartis (Inst); Pfizer (Inst); Rafael Pharmaceuticals (Inst); Roche/Genentech (Inst)
Travel, Accommodations, Expenses - Array BioPharma; BeiGene; Nouscom
Other Relationship - UpToDate
(OPTIONAL) Uncompensated Relationships - NCCN
 
Sarbajit Mukherjee
Research Funding - Ipsen (Inst)
Other Relationship - Esophageal Cancer Action Network (ECAN)
 
Anna Morena D'Alise
Employment - Nouscom
Patents, Royalties, Other Intellectual Property - Nouscom (Inst)
 
Guido Leoni
Employment - Nouscom
Patents, Royalties, Other Intellectual Property - Nouscom (Inst)
 
Loredana Siani
Employment - Nouscom
 
Elisa Scarselli
Employment - Nouscom
Leadership - Nouscom
Stock and Other Ownership Interests - Nouscom
Patents, Royalties, Other Intellectual Property - Nouscom (Inst)
 
Théa Faivre
Employment - Merck KGaA; Nouscom
 
Patricia Delaite
Employment - Nouscom
Leadership - Nouscom
Stock and Other Ownership Interests - Nouscom
 
Sven Gogov
Employment - Nouscom
Leadership - Nouscom
Stock and Other Ownership Interests - Nouscom
 
Marwan Fakih
Honoraria - Amgen
Consulting or Advisory Role - Amgen; Bayer; BMS; Eisai; GlaxoSmithKline; Incyte; Merck; Mirati Therapeutics; Nouscom; Pfizer; Roche/Genentech; Seagen; Taiho Pharmaceutical
Speakers' Bureau - Guardant Health
Research Funding - Amgen (Inst); Verastem (Inst)