The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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A phase 1/2a, multicenter, open-label study of CNA3103 (LGR5-targeted, autologous CAR-T cells) in patients with metastatic colorectal cancer (mCRC).
 
Jayesh Desai
Consulting or Advisory Role - Amgen (Inst); Bayer; BeiGene; Boehringer Ingelheim; Daiichi Sankyo Europe GmbH; GlaxoSmithKline; Merck KGaA; Novartis; Pfizer; Pierre Fabre; Roche/Genentech
Research Funding - AstraZeneca/MedImmune (Inst); BeiGene (Inst); Bionomics (Inst); Bristol-Myers Squibb (Inst); GlaxoSmithKline (Inst); Lilly (Inst); Novartis (Inst); Roche (Inst)
 
Jose Luis Iglesias
Consulting or Advisory Role - Amplia Therapeutics; Aucentra Therapeutics; Carina Biotech; Engine Biosciences; Epsilogen; HIberCell; Immunovaccine; Panavance Therapeutics
 
Lina T Jablonskis
Employment - Carina Biotech
Stock and Other Ownership Interests - BeiGene
 
Shaun McColl
Employment - Carina Biotech
Stock and Other Ownership Interests - Carina Biotech
Consulting or Advisory Role - Tizona Therapeutics, Inc.
Research Funding - Carina Biotech; Tizona Therapeutics, Inc.
Patents, Royalties, Other Intellectual Property - Carina Biotech
 
Simon C Barry
Leadership - Carina Biotech
Stock and Other Ownership Interests - Amgen; Carina Biotech; Commonwealth Serum Laboratories (CSL)
Consulting or Advisory Role - Carina Biotech
Research Funding - Carina Biotech
Patents, Royalties, Other Intellectual Property - Carina Biotech
 
Maria Pia Morelli
No Relationships to Disclose