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An open-label, multicenter study investigating RP3 oncolytic immunotherapy in combination with first- or second-line systemic atezolizumab plus bevacizumab in patients with locally advanced unresectable or metastatic hepatocellular carcinoma. |
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Research Funding - AstraZeneca; Hoosier Foundation; Koo Foundation; Replimune; TriSalus Life Sciences |
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Consulting or Advisory Role - AstraZeneca; Bristol-Myers Squibb; Daiichi Sankyo/Astra Zeneca; Exelixis; Five Prime Therapeutics; Pfizer |
Research Funding - Actuate Therapeutics (Inst); Astellas Pharma (Inst); AstraZeneca/MedImmune (Inst); Bristol-Myers Squibb (Inst); Clovis Oncology (Inst); Daiichi Sankyo/UCB Japan (Inst); Exelixis (Inst); Five Prime Therapeutics (Inst); innovent biologics (Inst); KAHR Medical (Inst); Merck Sharp & Dohme (Inst); Seagen (Inst) |
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No Relationships to Disclose |
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Consulting or Advisory Role - AstraZeneca; AstraZeneca; AstraZeneca; AstraZeneca; AstraZeneca; Basilea; Bayer; BeiGene; Boston Scientific; Bristol-Myers Squibb; BTG; Eisai; Incyte; Ipsen; Merck Serono; MSD; Roche; SERVIER; Taiho Oncology |
Research Funding - Beigene (Inst); Boston Scientific (Inst); Bristol-Myers Squibb (Inst); Exeliom Biosciences |
Travel, Accommodations, Expenses - Amgen; Bristol-Myers Squibb; Roche |
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Consulting or Advisory Role - AstraZeneca/MedImmune |
Speakers' Bureau - AstraZeneca/MedImmune; Roche |
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Stock and Other Ownership Interests - Replimune |
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Stock and Other Ownership Interests - Replimune |
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Consulting or Advisory Role - Boehringer Ingelheim |
Research Funding - Deutsche Forschungsgemeinschaft; Deutsche Krebshilfe; The Sander Foundation |
Patents, Royalties, Other Intellectual Property - 4 IP families re: oncolytic MeV |
Expert Testimony - Goverment |
Other Relationship - CanVirex |