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A phase 1, open-label, multicenter study evaluating MK-1084 as monotherapy and in combination with other therapies in patients with KRAS G12C mutant advanced solid tumors. |
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No Relationships to Disclose |
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Consulting or Advisory Role - AstraZeneca; Bristol-Myers Squibb; Knight Therapeutics/Biotoscana; Merck Sharp & Dohme; Pfizer; Roche |
Research Funding - AstraZeneca; Bristol-Myers Squibb/Celgene; Knight Therapeutics/Biotoscana; Merck; Pfizer; Roche |
Expert Testimony - AstraZeneca; Bristol-Myers Squibb; Roche |
Travel, Accommodations, Expenses - Bristol-Myers Squibb |
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Consulting or Advisory Role - AstraZeneca (Inst); Bayer (Inst); Janssen Oncology (Inst); Lilly (Inst); Novartis (Inst); Roche (Inst) |
Research Funding - Abbvie (Inst); ADC Therapeutics (Inst); Amgen (Inst); AstraZeneca (Inst); Bayer (Inst); Cellestia Biotech (Inst); Debiopharm Group (Inst); Incyte (Inst); Lilly (Inst); Loxo (Inst); MEI Pharma (Inst); Merck (Inst); Novartis (Inst); Pfizer (Inst); Philogen (Inst); Roche (Inst) |
Travel, Accommodations, Expenses - AstraZeneca; Incyte (Inst) |
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Consulting or Advisory Role - Amgen (Inst) |
Research Funding - BMS Brazil (Inst); MSD (Inst) |
Travel, Accommodations, Expenses - Lilly (Inst); Vifor pharma (Inst) |
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Travel, Accommodations, Expenses - MSD |
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Honoraria - Bms spain; Gilead Sciences; GlaxoSmithKline; MSD Oncology; Roche; Roche |
Consulting or Advisory Role - BeiGene |
Travel, Accommodations, Expenses - AstraZeneca/MedImmune; Bms Spain; MSD; Roche; Roche |
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Consulting or Advisory Role - Bristol-Myers Squibb; MSD |
Speakers' Bureau - Bristol-Myers Squibb; GlaxoSmithKline; MSD; Novartis; Roche |
Travel, Accommodations, Expenses - Bristol-Myers Squibb; GlaxoSmithKline; MSD; Novartis; Pierre Fabre; Roche |
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Consulting or Advisory Role - AstraZeneca; MSD; Roche |
Speakers' Bureau - Bayer; Bristol-Myers Squibb; MERCK |
Research Funding - Bristol-Myers Squibb (Inst); Novartis (Inst) |
Expert Testimony - AstraZeneca |
Travel, Accommodations, Expenses - Roche |
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Consulting or Advisory Role - Astellas Pharma; Bristol-Myers Squibb; Novartis; Pfizer; Roche; Takeda |
Speakers' Bureau - Astellas Pharma; Novartis; Pfizer; Roche; Takeda |
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Consulting or Advisory Role - Ikena Oncology; SK Life Sciences |
Research Funding - Alexo Therapeutics (Inst); Alkermes (Inst); Alpine Immune Sciences (Inst); Alpine Immune Sciences (Inst); Apexian Pharmaceuticals (Inst); Ascentage Pharma (Inst); Astellas Pharma (Inst); BeiGene (Inst); Biosplice (Inst); Celgene (Inst); Celgene (Inst); Constellation Pharmaceuticals (Inst); Coordination Therapeutics (Inst); CytomX Therapeutics (Inst); Epizyme (Inst); Forty Seven (Inst); Genmab (Inst); Genmab (Inst); Gilead Sciences (Inst); GlaxoSmithKline (Inst); Helsinn Therapeutics (Inst); Ikena Oncology (Inst); Ikena Oncology (Inst); Incyte (Inst); InhibRx (Inst); Innovent Biologics (Inst); Jounce Therapeutics (Inst); KSQ Therapeutics (Inst); LAM Therapeutics (Inst); Lilly (Inst); Livzon (Inst); Loxo (Inst); Macrogenics (Inst); Merck (Inst); Mersana (Inst); Northern Biologics (Inst); Odonate Therapeutics (Inst); Pfizer (Inst); Regeneron (Inst); Repare Therapeutics (Inst); Sapience Therapeutics (Inst); Sapience Therapeutics (Inst); Seagen (Inst); Servier (Inst); Shattuck Labs (Inst); SK Life Sciences (Inst); Symphogen (Inst); Tesaro (Inst); Tizona Therapeutics, Inc. (Inst) |
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Consulting or Advisory Role - GOG Foundation; MSD Oncology |
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Honoraria - AstraZeneca; Bristol-Myers Squibb; MSD Oncology; Roche/Genentech; Takeda |
Travel, Accommodations, Expenses - AstraZeneca; Pfizer; Roche |
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Research Funding - AstraZeneca; BMS; Genentech/Roche |
(OPTIONAL) Uncompensated Relationships - AstraZeneca; Genentech/Roche |
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Honoraria - AstraZeneca; Boehringer Ingelheim; Chugai Pharma; Daiichi Sankyo; Janssen; Lilly; MSD; Ono Pharmaceutical; Taiho Pharmaceutical; Takeda |
Research Funding - Abbvie; Amgen; AZD; Chugai Pharma; Daiichi Sankyo; MSD; Novartis |
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Honoraria - Amgen; AstraZeneca; BeiGene; Boehringer Ingelheim; Bristol-Myers Squibb Japan; Chugai Pharma; Daiichi Sankyo; GlaxoSmithKline; Janssen; Lilly; Merck KGaA; Merck Sharp & Dohme; Novartis; Ono Pharmaceutical; Pfizer; Roche; Taiho Pharmaceutical; Takeda |
Consulting or Advisory Role - Amgen; AstraZeneca; BeiGene; DaiichiSankyo; Janssen; Merck KGaA; MSD; Novartis; Pfizer |
Research Funding - Abbvie (Inst); Amgen (Inst); AstraZeneca (Inst); Bayer; BeiGene (Inst); Blueprint Medicines (Inst); Chugai Pharma (Inst); Daiichi Sankyo (Inst); Gilead Sciences (Inst); GlaxoSmithKline (Inst); Haihe Biopharma (Inst); Janssen (Inst); Lilly (Inst); Merck KGaA (Inst); Merck Sharp & Dohme (Inst); Novartis (Inst); Pfizer (Inst); Regeneron (Inst); Takeda (Inst); Turning Point Therapeutics (Inst) |
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Honoraria - GlaxoSmithKline; Merck Sharp & Dohme |
Consulting or Advisory Role - 1E Therapeutics; Clexio Biosciences Ltd.; GalMed Pharmacueticals; Gilboa Therapeutics; Simplivia |
Travel, Accommodations, Expenses - Merck Sharp & Dohme |
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Omar Orlando Castillo Fernandez |
Honoraria - ASOFARMA; AstraZeneca; Novartis; Pfizer; Roche Pharma AG |
Consulting or Advisory Role - Asofarma; GlaxoSmithKline; Janssen Oncology |
Research Funding - MSD Oncology; Novartis; Roche; Roche |
Travel, Accommodations, Expenses - Merck Serono; Novartis; Pfizer; Roche |
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Stock and Other Ownership Interests - Merck |
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Stock and Other Ownership Interests - Merck |
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Honoraria - Amgen; AstraZeneca; Bristol-Myers Squibb; Jazz Pharmaceuticals; Merck Sharp & Dohme; Mirati Therapeutics; Novartis Canada Pharmaceuticals Inc; Roche Canada; Takeda |
Consulting or Advisory Role - Amgen; AstraZeneca; Bayer; Bristol-Myers Squibb; EMD Serono; Fusion Pharmaceuticals; Janssen Oncology; Jazz Pharmaceuticals; Lilly; Merck Sharp & Dohme; Novartis; Pfizer; Roche Canada; Sanofi/Regeneron; Takeda |
Research Funding - Alkermes (Inst); Amgen (Inst); Astellas Pharma (Inst); AstraZeneca/MedImmune (Inst); Bold Therapeutics (Inst); Bristol-Myers Squibb (Inst); Fusion Pharmaceuticals (Inst); Janssen (Inst); Macrogenics (Inst); Merck Sharp & Dohme (Inst); Novartis (Inst) |