The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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ARC-8: Phase 1/1b randomized study of quemliclustat + gemcitabine/nab-paclitaxel ± zimberelimab in patients with treatment-naive metastatic pancreatic adenocarcinoma.
 
Zev A. Wainberg
Consulting or Advisory Role - Alligator Bioscience; Amgen; Arcus Biosciences; Astellas Pharma; AstraZeneca/MedImmune; Bayer; Bristol-Myers Squibb; Daiichi Sankyo/Astra Zeneca; Ipsen; Lilly; Merck; Merck KGaA; Novartis; Pfizer; PureTech; Seagen
Research Funding - Five Prime Therapeutics (Inst); Merck (Inst); Novartis (Inst); Pfizer (Inst); Plexxikon (Inst)
Travel, Accommodations, Expenses - Amgen; Bayer; Lilly; Merck
 
Gulam Abbas Manji
Honoraria - Celgene; Cend Therapeutics; Exelixis; Roche/Genentech
Consulting or Advisory Role - Cend Therapeutics; Exelixis; Ipsen; Roche/Genentech
Research Funding - Arcus Biosciences (Inst); BiolineRx (Inst); Merck (Inst); Plexxikon (Inst); Regeneron (Inst); Roche/Genentech (Inst)
Travel, Accommodations, Expenses - Celgene; Exelixis; Roche/Genentech
 
Nathan Bahary
Consulting or Advisory Role - AstraZeneca; Bristol-Myers Squibb; Incyte
 
Susanna Varkey Ulahannan
Consulting or Advisory Role - AstraZeneca; Eisai; IgM Biosciences
Research Funding - Abbvie (Inst); Adlai Nortye (Inst); ArQule (Inst); Astex Pharmaceuticals (Inst); AstraZeneca (Inst); atreca (Inst); Boehringer Ingelheim (Inst); Bristol-Myers Squibb (Inst); Celgene (Inst); CicloMed (Inst); Erasca, Inc (Inst); evelo biosciences (Inst); Exelixis (Inst); Exelixis (Inst); G1 Therapeutics (Inst); GlaxoSmithKline (Inst); IgM Biosciences (Inst); Incyte (Inst); Klus Pharma (Inst); Macrogenics (Inst); Merck (Inst); Mersana (Inst); NGM Biopharmaceuticals (Inst); OncoMed (Inst); Pfizer (Inst); Pionyr (Inst); Regeneron (Inst); Revolution Medicines (Inst); Synermore biologics (Inst); Takeda (Inst); Takeda (Inst); Tarveda Therapeutics (Inst); Tempest Therapeutics (Inst); Tesaro (Inst); Vigeo Therapeutics (Inst)
 
Shubham Pant
Consulting or Advisory Role - AskGene Pharma; Boehringer Ingelheim; Ipsen; Janssen; Novartis; Zymeworks
Research Funding - 4D Pharma (Inst); Amal Therapeutics (Inst); Arcus Biosciences (Inst); Astellas Pharma (Inst); bionte (Inst); Boehringer Ingelheim (Inst); Bristol-Myers Squibb (Inst); Elicio Therapeutics (Inst); Immuneering (Inst); ImmunoMET (Inst); Ipsen (Inst); Janssen (Inst); Lilly (Inst); Mirati Therapeutics (Inst); NGM Biopharmaceuticals (Inst); Novartis (Inst); Pfizer (Inst); Purple Biotech (Inst); Rgenix (Inst); Xencor (Inst); Zymeworks (Inst)
 
Nataliya Volodymyrivna Uboha
Stock and Other Ownership Interests - Exact Sciences (I); Natera (I)
Consulting or Advisory Role - Aptitude Health; Astellas Pharma; Astellas Pharma; AstraZeneca; BostonGene; Bristol Myers Squibb Foundation; Bristol-Myers Squibb/Roche; Eisai/MSD; Elevation Oncology; GRAIL; Helsinn Therapeutics; Ipsen; ipsen; Pfizer
Research Funding - EMD Serono (Inst); ipsen (Inst)
 
Paul Eliezer Oberstein
Consulting or Advisory Role - Amal Therapeutics; Aravive; AstraZeneca; AstraZeneca; Merck; QED Therapeutics; Rubius Therapeutics
Speakers' Bureau - AstraZeneca
Research Funding - Amal Therapeutics (Inst); Arcus Biosciences (Inst); Merck (Inst); Novartis (Inst); Rafael Pharmaceuticals (Inst); Roche/Genentech (Inst); Zai Lab (Inst)
Expert Testimony - Ipsen
Travel, Accommodations, Expenses - Merck
 
Lawrence H Lu
Employment - Arcus Biosciences
Stock and Other Ownership Interests - Arcus Biosciences
Travel, Accommodations, Expenses - Arcus Biosciences
Other Relationship - Arcus Biosciences
 
Jennifer R. Scott
Employment - Arcus Biosciences
Stock and Other Ownership Interests - Arcus Biosciences
Honoraria - Arcus Biosciences
 
Wilson Wu
Employment - Arcus Biosciences
Stock and Other Ownership Interests - Arcus Biosciences
Honoraria - Arcus Biosciences
 
Joon Rhee
Employment - Gilead Sciences
Stock and Other Ownership Interests - Gilead Sciences
Travel, Accommodations, Expenses - Gilead Sciences
 
Dimitry S. A. Nuyten
Employment - Arcus Biosciences; Nektar; Olema Pharmaceuticals (I); Turning Point Therapeutics (I)
Leadership - Arcus Biosciences; Nektar; Olema Pharmaceuticals (I)
Stock and Other Ownership Interests - Abbott Laboratories; Allogene Therapeutics; Amgen; Arcus Biosciences; AstraZeneca; BeiGene; Biomarin; Bristol-Myers Squibb/Celgene; Chinook Therapeutics; Fate Therapeutics; Genmab; Johnson & Johnson/Janssen; Kezar Life Sciences; Merck; Merck; Moderna Therapeutics; Nektar; Novo Nordisk; Pfizer; Pyxis; Radius Health; Roche; Sangamo Therapeutics; Seagen; Synlogic; Synlogic; Teva; Turning Point Therapeutics (I); United Health Group; Viatris
Patents, Royalties, Other Intellectual Property - My spouse was VP of development and with that shareholder of Peloton Therapeutics. Merck's acquisition cam with milestone payments based on commercial milestones for belzutifan (Welireg). With that we anticipate to receive (consider similar to royalty) fu (I); See https://patents.justia.com/inventor/dimitry-serge-antoine-nuyten
Travel, Accommodations, Expenses - Arcus Biosciences
 
Eileen Mary O'Reilly
Consulting or Advisory Role - AstraZeneca; Autem Medical (I); Boehringer Ingelheim; Eisai (I); Exelixis (I); Genentech/Roche (I); Helio Health (I); Incyte (I); Ipsen; Merck; Novartis; QED Therapeutics (I); Yiviva (I); Yiviva (I)
Research Funding - Arcus Ventures (Inst); AstraZeneca/MedImmune (Inst); BioNTech (Inst); Bristol Myers Squibb (Inst); Bristol Myers Squibb (Inst); Celgene (Inst); Genentech (Inst); Helsinn Healthcare (Inst); Puma Biotechnology (Inst); QED Therapeutics (Inst); Roche (Inst); Yiviva (Inst)
(OPTIONAL) Uncompensated Relationships - Thetis Pharma