The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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Initial data from a phase 1, first-in-human clinical trial for T-Plex, a multiplexed, enhanced T cell receptor-engineered T cell therapy (TCR-T) for solid tumors.
 
Sajeve Samuel Thomas
Speakers' Bureau - Bms; Merck; Natera; Pfizer; SpringWorks Therapeutics
 
Brian Pico
Employment - Memorial Healthcare System
Consulting or Advisory Role - Janssen Scientific Affairs
Research Funding - Immune-Onc Therapeutics (Inst); TScan Therapeutics (Inst)
 
Brian S. Henick
Honoraria - DAVA Oncology; OncLive/MJH Life Sciences
Consulting or Advisory Role - AstraZeneca; Bristol-Myers Squibb; Genentech/Roche; IDEAYA Biosciences; Jazz Pharmaceuticals; Regeneron; Sorrento Therapeutics
Research Funding - Genentech/Roche (Inst); Johnson & Johnson/Janssen (Inst); NexImmune (Inst); Stand Up 2 Cancer (Inst); V Foundation (Inst)
 
Rom Leidner
Consulting or Advisory Role - AstraZeneca; Bristol-Myers Squibb; CDR-Life; Merck; VIR Biotechnology
Research Funding - AstraZeneca; Bristol-Myers Squibb; Incyte
Travel, Accommodations, Expenses - Bristol-Myers Squibb
 
Yazan Samhouri
No Relationships to Disclose
 
James Isaacs
Research Funding - Bristol-Myers Squibb/Medarex (Inst); Merck (Inst); TScan Therapeutics (Inst)
 
Jared Weiss
Stock and Other Ownership Interests - Achilles Therapeutics (I); Enfuego Therapeutics; Lyell Immunopharma; Nektar; Nuvalent, Inc.; Vertex; Vesselon
Consulting or Advisory Role - abbvie; Amgen; AstraZeneca; BeiGene; EMD Serono; G1 Therapeutics; Genentech; Genmab; Gilead Sciences; Jounce Therapeutics; Merck; Nanobiotix; PDS Biotechnology; Regeneron; Sanofi/Aventis
Research Funding - AstraZeneca/MedImmune (Inst); Boehringer Ingelheim (Inst); G1 Therapeutics (Inst); Immunicum (Inst); Loxo/Lilly (Inst); Merck (Inst); Mirati Therapeutics (Inst); PDS Biotechnology (Inst); Sumitomo Dainippon Pharma Oncology (Inst)
Travel, Accommodations, Expenses - Mirati Therapeutics
 
Michael E. Hurwitz
Employment - Arvinas (I); Faeth Therapeutics (I); Gamida Cell (I); Pfizer (I)
Stock and Other Ownership Interests - Arvinas (I)
Consulting or Advisory Role - Affini-T Therapeutics; Bristol-Myers Squibb/Celgene; crispr therapeutics; Exelixis; Janssen; Nektar; pliant; Regeneron; TScan Therapeutics
Research Funding - Achilles Therapeutics; Achilles Therapeutics; Apexigen; Astellas Pharma; AstraZeneca/MedImmune; Bayer; Bristol-Myers Squibb; Corvus Pharmaceuticals; Endocyte; Endocyte; Genentech; Genmab; Innocrin Pharma; Iovance Biotherapeutics; Lilly; Lyell Immunopharma; Lyell Immunopharma; Merck; Nektar; Novartis; Novartis; Pfizer; Progenics; Sanofi/Aventis; Seagen; Synthekine; Torque; Unum Therapeutics; Xilio Therapeutics
 
Jaspreet Singh Grewal
Honoraria - Curio Science; Eisai
Consulting or Advisory Role - Eisai
Speakers' Bureau - Bayer; BMS GmbH & Co. KG; Ipsen
Expert Testimony - Monsanto
 
Jason J. Luke
Stock and Other Ownership Interests - Actym Therapeutics; Alphamab; Arch Oncology; Kanaph Therapeutics; Mavu Pharmaceutical; NeoTX; NeoTX; Onc.AI; Pyxis; STipe Therapeutics; Tempest Therapeutics
Consulting or Advisory Role - 7 Hills Pharma; Abbvie; Alnylam; Alphamab; Bayer; Bright Peak Therapeutics; Bristol-Myers Squibb; Checkmate Pharmaceuticals; Codiak Biosciences; Crown Bioscience; CStone Pharmaceuticals; Day One Therapeutics; EMD Serono; Endeavor BioMedicines; Flame Biosciences; Genentech; Gilead Sciences; Hotspot Therapeutics; Immunocore; Incyte; Inzen Therapeutics; Janssen; Kadmon; KSQ Therapeutics; Merck; Nektar; Novartis; Onc.AI; Partner Therapeutics; Pfizer; Reflexion Medical; Regeneron; Ribon Therapeutics; Rubius Therapeutics; SERVIER; Silicon Therapeutics; STINGthera; STipe Therapeutics; Synlogic; Synthekine; Tempest Therapeutics; Tesaro; TRex Bio; Werewolf Therapeutics; Xencor; Xilio Therapeutics
Research Funding - Abbvie (Inst); Agios (Inst); Array BioPharma (Inst); Astellas Pharma (Inst); BioNTech (Inst); Bristol-Myers Squibb (Inst); Corvus Pharmaceuticals (Inst); EMD Serono (Inst); Fstar (Inst); Genmab (Inst); Ikena Oncology (Inst); Immatics (Inst); Incyte (Inst); Kadmon (Inst); KAHR Medical (Inst); Macrogenics (Inst); Merck (Inst); Moderna Therapeutics (Inst); Nektar (Inst); NextCure (Inst); Numab (Inst); Replimune (Inst); Rubius Therapeutics (Inst); Scholar Rock (Inst); Spring bank (Inst); Synlogic (Inst); Takeda (Inst); Tizona Therapeutics, Inc. (Inst); Trishula Therapeutics (Inst); Xencor (Inst)
Patents, Royalties, Other Intellectual Property - Serial #15/612,657 (Cancer Immunotherapy),; Serial #PCT/US18/36052 (Microbiome Biomarkers for Anti-PD-1/PD-L1 Responsiveness: Diagnostic, Prognostic and Therapeutic Uses Thereof)
Travel, Accommodations, Expenses - Array BioPharma; Bristol-Myers Squibb; EMD Serono; Janssen; Merck; Mersana; Novartis; Pyxis; Reflexion Medical; Xilio Therapeutics
 
Shrikanta Chattopadhyay
Employment - TScan Therapeutics
Stock and Other Ownership Interests - TScan Therapeutics
 
Yun Wang
Employment - TScan Therapeutics
Stock and Other Ownership Interests - TScan Therapeutics
 
Marlyane Motta
Employment - TScan Therapeutics
Stock and Other Ownership Interests - TScan Therapeutics
 
Jim Murray
Employment - TScan Therapeutics
Stock and Other Ownership Interests - TScan Therapeutics
Travel, Accommodations, Expenses - TScan Therapeutics
 
Debora Barton
Employment - Advanced Accelerator Applications; Carisma Therapeutics; Iovance Biotherapeutics; TScan Therapeutics
Leadership - Arovella Therapeutics
Stock and Other Ownership Interests - Advanced Accelerator Applications; Arovella Therapeutics; Carisma Therapeutics; Iovance Biotherapeutics; NKILT Therapeutics; TScan Therapeutics
 
Dawn Pinchasik
Employment - TScan Therapeutics
Stock and Other Ownership Interests - TScan Therapeutics
 
Gavin MacBeath
Employment - TScan Therapeutics
Stock and Other Ownership Interests - TScan Therapeutics
 
Justin C Moser
Honoraria - Caris Life Sciences; Daiichi Sankyo/Lilly; TGen
Consulting or Advisory Role - Adagene; Amunix; Boxer Capitol; Bristol Myers Squibb Foundation; Genome Insight; Imaging Endpoints; Incyte; IQvia; Novotech; Oberland Capital; Red Arrow Therapeutics; Thirona Biosciences; Werewolf Therapeutics (Inst)
Speakers' Bureau - Caris Life Sciences; Castle Biosciences; Immunocore
Research Funding - Adaptimmune (Inst); Agenus (Inst); Alpine Immune Sciences (Inst); Amgen (Inst); BioEclipse Therapeutics (Inst); Fate Therapeutics (Inst); Fujifilm (Inst); Genentech (Inst); IDEAYA Biosciences (Inst); ImmuneSensor Therapeutics (Inst); Iovance Biotherapeutics (Inst); Istari Oncology (Inst); Nektar (Inst); Novocure (Inst); Repertoire Immune Medicines (Inst); Rubius Therapeutics (Inst); Senhwa Biosciences (Inst); Simcha Therapeutics (Inst); Storm Therapeutics (Inst); Synthorx (Inst); T-Scan Therapeutics (Inst); Trishula Therapeutics (Inst); University of Arizona (Inst); Werewolf Therapeutics (Inst); Y-mAbs Therapeutics (Inst)
Other Relationship - Caris Life Sciences