The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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Type II RAF inhibitor tovorafenib in relapsed/refractory pediatric low-grade glioma (pLGG): Reversible decreases in growth velocity in the phase 2 FIREFLY-1 trial.
 
Cassie Kline
Research Funding - Bristol-Myers Squibb (Inst); Chimerix (Inst); Curis (Inst); Day One Therapeutics (Inst); Ipsen (Inst); Kazia Therapeutics (Inst); Midatech Pharma (Inst); Regeneron (Inst)
 
Angela Jae Waanders
Research Funding - Day One Biopharmaceuticals (Inst)
 
David Simon Ziegler
Consulting or Advisory Role - Accendatech; Alexion Pharmaceuticals; Amgen; AstraZeneca/Merck; Bayer; Day One Biopharmaceuticals; FivePhusion; Norgine; Novartis
Research Funding - Accendatech (Inst)
Travel, Accommodations, Expenses - Bayer
 
Lindsay Baker Kilburn
Employment - Children's National Hospital; Kaiser Permanente (I)
Stock and Other Ownership Interests - Onconova Therapeutics (I)
Consulting or Advisory Role - Blueprint Medicines
Research Funding - Bristol-Myers Squibb/Celgene (Inst); Chimerix (Inst); Day One Biopharmaceuticals (Inst); Helsinn Therapeutics (Inst); Novartis (Inst); Regeneron (Inst); SonaCare Medical (Inst); SpringWorks Therapeutics (Inst)
 
Karsten Nysom
Consulting or Advisory Role - Bayer; Lilly
 
Jasper van der Lugt
No Relationships to Disclose
 
Timothy E. Hassall
Research Funding - Dat One Biopharmaceuticals (Inst)
 
Nicolas U. Gerber
No Relationships to Disclose
 
Devorah Segal
Consulting or Advisory Role - Alexion Pharmaceuticals
Research Funding - Takeda
 
Valérie Larouche
Honoraria - Alexion Pharmaceuticals
Consulting or Advisory Role - Alexion Pharmaceuticals
Research Funding - Day One Biopharmaceuticals (Inst)
 
Sabine Mueller
Consulting or Advisory Role - Roche
Research Funding - Blueprint Medicines (Inst); Bristol Meyer Scribbs (Inst); Chimerix (Inst); Curis Pharamceuticals (Inst); DayOne Pharmaceuticals (Inst); Pfizer (Inst); Regeneron (Inst); SonaCare Medical (Inst)
 
Ashley Walter
Employment - Day One Biopharmaceuticals
Stock and Other Ownership Interests - Day One Biopharmaceuticals
 
Peter Manley
Employment - Day One Biopharmaceuticals; Repare Therapeutics
Stock and Other Ownership Interests - Repare Therapeutics
Travel, Accommodations, Expenses - Day One Biopharmaceuticals; Repare Therapeutics
 
Lisa McLeod
Employment - Day One Biopharmauticals
Stock and Other Ownership Interests - Day One Biopharmeceuticals
 
Daniel B Landi
Research Funding - Day One Biopharmaceuticals (Inst)