The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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Phase 1 safety and efficacy of IMC-F106C, a PRAME × CD3 ImmTAC bispecific, in post-checkpoint cutaneous melanoma (CM).
 
Omid Hamid
Stock and Other Ownership Interests - Bactonix
Honoraria - Bristol-Myers Squibb; Immunocore; Novartis; Pfizer; Regeneron
Consulting or Advisory Role - Alkermes; Amgen; Bactonix; BeiGene; BioAtla; Bristol-Myers Squibb; Eisai; Genentech; Georgiamune; GigaGen; GlaxoSmithKline; Grit Biotechnology; Idera; Immunocore; Incyte; Instil Bio; IO Biotech; Iovance Biotherapeutics; Janssen; KSQ Therapeutics; Merck; Moderna Therapeutics; NGM Biopharmaceuticals; Novartis; Obsidian Therapeutics; Pfizer; Regeneron; Roche; Sanofi; Seagen; Tempus; Vial; Zelluna
Speakers' Bureau - Bristol-Myers Squibb; Immunocore; Novartis; Pfizer; Regeneron
Research Funding - Aduro Biotech (Inst); Akeso Biopharma (Inst); Amgen (Inst); Arcus Biosciences (Inst); Bioatla (Inst); Bristol-Myers Squibb (Inst); CytomX Therapeutics (Inst); Exelixis (Inst); Genentech (Inst); GlaxoSmithKline (Inst); Idera (Inst); Immunocore (Inst); Incyte (Inst); Iovance Biotherapeutics (Inst); Merck (Inst); Merck Serono (Inst); Moderna Therapeutics (Inst); NextCure (Inst); Novartis (Inst); Pfizer (Inst); Regeneron (Inst); Roche (Inst); Sanofi (Inst); Seagen (Inst); Torque (Inst); Zelluna (Inst)
 
Anja Williams
Consulting or Advisory Role - Ellipses Pharma
 
Juanita Suzanne Lopez
Consulting or Advisory Role - Basilea; CureTeq; Ellipses Pharma; Genmab; GlaxoSmithKline; Novartis; Pierre Fabre; Roche/Genentech
Research Funding - Astex Pharmaceuticals (Inst); Basilea (Inst); Roche/Genentech (Inst)
Travel, Accommodations, Expenses - Basilea; Roche/Genentech
 
Daniel Olson
Consulting or Advisory Role - Alphasights; Expert Consulting Services; Gerson Lehrman Group; Iovance Biotherapeutics; MJH Life Sciences; Novartis; Novartis; Obsidian Therapeutics
Travel, Accommodations, Expenses - Iovance Biotherapeutics
 
Takami Sato
Consulting or Advisory Role - Immunocore, Castle Biosciences
Research Funding - Immunocore, Verastem (Inst)
 
Heather May Shaw
Consulting or Advisory Role - Bristol-Myers Squibb; CDR-Life; Genzyme; Mallinckrodt/Therakos; MSD Oncology; Novartis; Regeneron; Scancell Ltd.
Speakers' Bureau - AstraZeneca; Bristol-Myers Squibb; Eisai; Merck Sharp & Dohme; Novartis; Sanofi
Research Funding - Agenus (Inst); AstraZeneca/MedImmune (Inst); Genmab (Inst); IDEAYA Biosciences (Inst); Idera (Inst); Immunocore (Inst); Iovance Biotherapeutics (Inst); Merck Sharp & Dohme (Inst); Novartis (Inst); Roche (Inst); Scancell Ltd. (Inst)
Expert Testimony - Bristol-Myers Squibb
Travel, Accommodations, Expenses - Agenus; Bristol-Myers Squibb; Merck Sharp & Dohme; Regeneron
(OPTIONAL) Uncompensated Relationships - iOnctura
 
Claire Frances Friedman
Honoraria - GlaxoSmithKline; MJH Healthcare Holdings, LLC
Consulting or Advisory Role - AADi; Arch Oncology; Bristol Myers Squibb; Loxo/Lilly
Research Funding - AstraZeneca (Inst); Bristol-Myers Squibb (Inst); Daiichi Sankyo/UCB Japan (Inst); Genentech (Inst); Hotspot Therapeutics (Inst); Immunocore (Inst); Marengo Therapeutics (Inst); Merck (Inst); Seagen (Inst)
Travel, Accommodations, Expenses - Puma Biotechnology
(OPTIONAL) Uncompensated Relationships - Genentech; Merck
 
Fiona Thistlethwaite
Honoraria - Bayer
Consulting or Advisory Role - Bristol-Myers Squibb; Enara Bio; GlaxoSmithKline; Guidepoint Pharmacy; Immatics; Ixaka; Janssen; Leucid Bio; Pfizer (Inst); Scenic Biotech; T-Knife
Research Funding - 3-V Biosciences (Inst); Abbvie (Inst); Actuate Therapeutics (Inst); Adaptimmune (Inst); Adaptimmune (Inst); Agalimmune (Inst); AstraZeneca (Inst); AVEO (Inst); Bayer (Inst); BerGenBio (Inst); Blueprint Medicines (Inst); Blueprint Medicines (Inst); Boehringer Ingelheim (Inst); Bristol-Myers Squibb (Inst); Bristol-Myers Squibb (Inst); Carrick Therapeutics (Inst); CytomX Therapeutics (Inst); Eisai (Inst); GenMab (Inst); GlaxoSmithKline (Inst); GlaxoSmithKline (Inst); Ignyta (Inst); Immutep (Inst); Incyte (Inst); Janssen (Inst); kinex (Inst); Lilly (Inst); Macrogenics (Inst); MedImmune (Inst); Merck (Inst); Millenium Pharamceuticals (Inst); MSD (Inst); Novartis (Inst); Octimet (Inst); Orion (Inst); Pfizer (Inst); Redx Pharma (Inst); Roche (Inst); Roche (Inst); Sierra Oncology (Inst); Synthon (Inst); Takeda (Inst); Tarveda Therapeutics (Inst)
Travel, Accommodations, Expenses - Ixaka; Scenic Biotech
Other Relationship - iMatch
 
Mark R. Middleton
Consulting or Advisory Role - Alkermes; Bayer; Boehringer Ingelheim; Bristol-Myers Squibb; GRAIL (Inst); Immunocore
Research Funding - Amgen (Inst); AstraZeneca (Inst); Bristol-Myers Squibb (Inst); GRAIL (Inst); Immunocore (Inst); Infinitopes (Inst); Merck (Inst); Novartis (Inst); Pfizer (Inst); Regeneron (Inst); Replimune (Inst); Roche (Inst); Salvarx (Inst)
(OPTIONAL) Uncompensated Relationships - GenesisCare
 
Celeste Lebbe
Honoraria - Amgen; Bristol-Myers Squibb; Incyte; MSD; Novartis; Pfizer; Pierre Fabre; Roche; Sanofi
Consulting or Advisory Role - Amgen; Bristol-Myers Squibb; Inflax; Merck Serono; MSD; Novartis; Pierre Fabre; Roche; Sanofi
Speakers' Bureau - Amgen; Bristol-Myers Squibb; Incyte; MSD; Novartis; Pfizer; Pierre Fabre; Roche; Sanofi
Research Funding - Bristol-Myers Squibb (Inst); Roche (Inst)
Travel, Accommodations, Expenses - Bristol-Myers Squibb; MSD; Novartis; Pierre Fabre; Roche; Sanofi
Other Relationship - Avantis Medical Systems; BMS; InflaRx; Jazz Pharmaceuticals; MSD; Novartis; Pierre Fabre; Sanofi
 
Vincent T Ma
Honoraria - Conquer Cancer, the ASCO Foundation; Society for Immunotherapy of Cancer
Consulting or Advisory Role - Bristol Myers Squibb; General Dynamics Information Technology; Immunocore; Incyte; Partner Therapeutics; Regeneron; Replimune; Targeted Oncology; Teiko.bio
Research Funding - AIQ Solutions (Inst); C4 Therapeutics (Inst); Fujifilm (Inst); Immunocore (Inst); Innate Pharma (Inst); Jounce Therapeutics (Inst); Natera (Inst); Seagen (Inst); Top Alliance BioScience (Inst); Y-mAbs Therapeutics (Inst)
Travel, Accommodations, Expenses - Incyte
 
Benjamin Izar
Consulting or Advisory Role - Immunocore.
 
Peter Kar Han Lau
Employment - George Clincal
Honoraria - Bristol-Myers Squibb; Lilly; MSD
Consulting or Advisory Role - Immunocore; MSD
Research Funding - Ambrx (Inst); AstraZeneca (Inst); Beigene (Inst); Bristol Myers Squibb (Inst); Gilead Sciences (Inst); Iksuda (Inst); Immunocore (Inst); Lilly (Inst); MSD (Inst); Olema Oncology (Inst); Pfizer (Inst); Pimera (Inst); Roche/Genentech (Inst)
Travel, Accommodations, Expenses - AstraZeneca; MSD; Roche/Genentech
 
Oliver Edgar Bechter
No Relationships to Disclose
 
Peter Kirk
Employment - Immunocore
Stock and Other Ownership Interests - Immunocore
 
Yuan Yuan
Employment - Immunocore
Stock and Other Ownership Interests - Immunocore
Consulting or Advisory Role - G1 Therapeutics (I); Precision Scientific (I)
 
Shannon Marshall
Employment - Immunocore
Stock and Other Ownership Interests - Immunocore
 
Diwakar Davar
Honoraria - ACM Biolabs; Clinical Care Options (CCO); Gerson Lehrman Group; Medical Learning Group; Merck; Xilio Therapeutics
Consulting or Advisory Role - ACM Bio; Ascendis Pharma; Clinical Care Options; Gerson Lehrman Group; Replimune; TriSalus Life Sciences; Xilio Therapeutics
Speakers' Bureau - Castle Biosciences
Research Funding - Arcus Biosciences; CellSight Technologies; Checkmate Pharmaceuticals; GlaxoSmithKline; Merck; Merck; Zucero Therapeutics (Inst)
Patents, Royalties, Other Intellectual Property - Application No.: 63/124,231; Enteric Microbiotype Signatures of Immune-related Adverse Events and Response in Relation to Anti-PD-1 Immunotherapy