The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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Updated results and subgroup analysis by presence of liver metastases of a phase I/II study of the EP4 antagonist vorbipiprant with the anti-PD-1 balstilimab in mismatch-repair-proficient and microsatellite stable (pMMR/MSS) chemorefractory metastatic colorectal cancer (mCRC).
 
Filippo Pietrantonio
Honoraria - Amgen; Astellas Pharma; AstraZeneca; Bayer; Bristol-Myers Squibb; Daiichi-Sankyo; Ipsen; Johnson&Johnson; Merck Serono; MSD Oncology; Pierre Fabre; Rottapharm Biotech; Seagen; SERVIER; Takeda
Consulting or Advisory Role - Amgen; Bayer; GlaxoSmithKline; Janssen; Merck Serono; MSD Oncology; Rottapharm Biotech; SERVIER; Takeda
Research Funding - Agenus (Inst); Amgen (Inst); Astrazeneca (Inst); Bristol-Myers Squibb (Inst); Incyte (Inst); Lilly (Inst)
Travel, Accommodations, Expenses - Merck Serono; Pierre Fabre
 
Federica Morano
Honoraria - Lilly; Pierre Fabre; SERVIER
Research Funding - Incyte (Inst)
Travel, Accommodations, Expenses - Daiichi Sankyo/Astra Zeneca
 
Monica Niger
Honoraria - Accademia Nazionale Di Medicina (ACCMED); Incyte; medpoint SRL; Sandoz; SERVIER
Consulting or Advisory Role - Basilea Pharmaceutical; EMD Serono; Incyte; MSD/AstraZeneca; SERVIER; Taiho Pharmaceutical
Travel, Accommodations, Expenses - AstraZeneca
 
Filippo Ghelardi
No Relationships to Disclose
 
Claudia Chiodoni
No Relationships to Disclose
 
Michele Palazzo
No Relationships to Disclose
 
Eleonora Cristarella
No Relationships to Disclose
 
Nadia Brambilla
Employment - Rottapharm Biotech
 
Elena Benincasa
Employment - Merck KGaA
Consulting or Advisory Role - Rottapharm Biotech
 
Giampaolo Giacovelli
Employment - Rottapharm Biotech
 
Cristina Vitalini
Employment - Rottapharm Biotech
 
Federica Girolami
Employment - Rottapharm Biotech
 
Lucio C Rovati
Employment - Rottapharm Biotech
Leadership - Rottapharm Biotech
Stock and Other Ownership Interests - Rottapharm Biotech