The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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Tucatinib-trastuzumab-capecitabine for treatment of leptomeningeal metastasis in HER2+ breast cancer: TBCRC049 phase 2 study results.
 
Barbara Jane O'Brien
Consulting or Advisory Role - Plus Therapeutics
Research Funding - EMD Serono (Inst); Kintara (Inst)
 
Rashmi Krishna Murthy
Honoraria - AstraZeneca; Genentech; Novartis; Puma Biotechnology; Sanofi; Seagen
Consulting or Advisory Role - AstraZeneca; Genentech/Roche; Novartis; Pfizer; Puma Biotechnology; Sanofi; Seagen
Research Funding - AstraZeneca (Inst); Daiichi Sankyo (Inst); EMD Serono (Inst); Genentech/Roche (Inst); Pfizer (Inst); Seagen (Inst)
 
Donald A. Berry
Employment - Berry Consultants
Leadership - Berry Consultants
Stock and Other Ownership Interests - Berry Consultants
Consulting or Advisory Role - Berry Consultants
Travel, Accommodations, Expenses - Berry Consultants
 
Akshara Singareeka Raghavendra
No Relationships to Disclose
 
Maria Gule-Monroe
No Relationships to Disclose
 
Jason M. Johnson
No Relationships to Disclose
 
Jill Schwartz-Gomez
No Relationships to Disclose
 
Ariel Topletz-Erickson
Employment - Seagen
Stock and Other Ownership Interests - Seagen
 
Mina Lobbous
No Relationships to Disclose
 
Michelle E. Melisko
Stock and Other Ownership Interests - Merrimack (I)
Speakers' Bureau - AstraZeneca (I); Genentech (I); Gilead Sciences (I)
Research Funding - DAEHWA Pharmaceutical (Inst); Novartis (Inst); OBI Pharma (Inst)
Patents, Royalties, Other Intellectual Property - Multiple patents related to immunoliposomal drugs being studied and potentially brought to market by Merrimack (I)
Expert Testimony - GlaxoSmithKline
 
Aki Morikawa
Consulting or Advisory Role - Eisai; Lilly; Seagen
Research Funding - Dantari Pharmaceuticals (Inst); Eisai (Inst); Eisai (Inst); Eisai (Inst); F. Hoffmann LaRoche (Inst); Freenome (Inst); Genentech/Roche (Inst); Lilly (Inst); Merck Sharp & Dohme Corp. (Inst); Merrimack (Inst); Millenium Pharamceuticals (Inst); Molecular Templates (Inst); Novartis (Inst); Pfizer (Inst); Seagen (Inst); Suzhou Zanrong Pharma (Inst); Tempus (Inst)
Other Relationship - Taiho Pharmaceutical
(OPTIONAL) Uncompensated Relationships - Puma Biotechnology
 
Sherise D. Ferguson
No Relationships to Disclose
 
John Frederick de Groot
Employment - Alaunos Therapeutics (I); Brii Biosciences (I)
Stock and Other Ownership Interests - Alaunos Therapeutics (I); Brii Biosciences (I); WuXi Biologics
Consulting or Advisory Role - Alpha Pharmaceutical; Aucentra Therapeutics; Bioasis Technologies; CarThera; Chimerix; Cure Brain Cancer Foundation; InSightec; Karyopharm Therapeutics; Kazia Therapeutics; Kintara Therapeutics; Merck; Midatech Pharma; Monteris Medical; Mundipharma Research; Samus Therapeutics; Sapience Therapeutics; SERVIER; Sumitomo Dainippon Pharma Oncology; Telix Pharmaceuticals; VBI Vaccines
Research Funding - CarThera (Inst); Haihe Pharmaceutical (Inst); Taiho Pharmaceutical (Inst)
Other Relationship - Chimerix; VBI Vaccines
 
Ian E. Krop
Employment - PureTech (I)
Leadership - PureTech (I)
Stock and Other Ownership Interests - PureTech (I)
Honoraria - AstraZeneca; Daiichi Sankyo
Consulting or Advisory Role - AstraZeneca; Daiichi Sankyo; Genentech/Roche; Merck; Novartis; Seagen
Research Funding - Genentech (Inst); Macrogenics (Inst); Pfizer (Inst)
Patents, Royalties, Other Intellectual Property - anti-murine CD19 monoclonal antibody licensed to PharMingen
 
Vicente Valero
Honoraria - AstraZeneca; Genentech/Roche; Novartis
Consulting or Advisory Role - AstraZeneca; Genentech/Roche; Novartis
Travel, Accommodations, Expenses - Genentech/Roche
 
Mothaffar F. Rimawi
Consulting or Advisory Role - AstraZeneca; Macrogenics; Novartis; Pfizer; Sermonix Pharmaceuticals
 
Antonio C. Wolff
Patents, Royalties, Other Intellectual Property - Antonio Wolff has been named as inventor on one or more issued patents or pending patent applications relating to methylation in breast cancer, and has assigned his rights to JHU, and participates in a royalty sharing agreement with JHU.
 
Debashish Tripathy
Consulting or Advisory Role - Ambrx; AstraZeneca; Genomic Health; Gilead Sciences; GlaxoSmithKline; Menarini; Novartis; OncoPep; Personalis; Pfizer; Roche; Sermonix Pharmaceuticals
Research Funding - Ambrx (Inst); Novartis (Inst); Pfizer (Inst); Polyphor (Inst)
Travel, Accommodations, Expenses - AstraZeneca; Novartis
 
Nancy U. Lin
Stock and Other Ownership Interests - Artera
Consulting or Advisory Role - Artera; AstraZeneca; Blueprint Medicines; Daiichi Sankyo; Eisai; Johnson & Johnson/Janssen; Menarini; Olema Pharmaceuticals; Pfizer; Seagen
Research Funding - Genentech (Inst); Merck (Inst); Olema Pharmaceuticals (Inst); Pfizer (Inst); Seagen (Inst); Zion Pharma (Inst)
Patents, Royalties, Other Intellectual Property - Royalties for chapter in Up-to-Date regarding management of breast cancer brain metastases; Royalties, Jones & Bartlett
Travel, Accommodations, Expenses - Olema Pharmaceuticals
 
Erica Michelle Stringer-Reasor
Consulting or Advisory Role - AstraZeneca; Daiichi Sankyo/Astra Zeneca; Lilly; Merck; Merck; Novartis; Pumas-AI; Pumas-AI; Seagen
Research Funding - Susan G. Komen for the Cure; V Foundation