The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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A phase 2 study of amivantamab plus lazertinib in patients with EGFR-mutant lung cancer and active central nervous system disease.
 
Helena Alexandra Yu
Consulting or Advisory Role - Abbvie; AstraZeneca; Black Diamond Therapeutics; Blueprint Medicines; C4 Therapeutics; Cullinan Oncology; Daiichi Sankyo; Janssen; Novocure; Taiho Oncology
Research Funding - Astellas Pharma (Inst); AstraZeneca (Inst); Black Diamond Therapeutics (Inst); Blueprint Medicines (Inst); Cullinan Oncology (Inst); Daiichi Sankyo (Inst); Erasca, Inc (Inst); Janssen Oncology (Inst); Lilly (Inst); Novartis (Inst); Pfizer (Inst); Systimmune (Inst)
Other Relationship - Astellas Pharma
 
Monica F Chen
Stock and Other Ownership Interests - docs; FIGS; Nordisk; Quest Diagnostics
Research Funding - ASCO; NIH
Travel, Accommodations, Expenses - AACR; ASCO
 
Angela B. Hui
No Relationships to Disclose
 
Noura J. Choudhury
Consulting or Advisory Role - Abbvie; G1 Therapeutics; Harpoon therapeutics; Sanofi
Research Funding - Abbvie (Inst); Amgen (Inst); Harpoon therapeutics (Inst); Merck (Inst); Monte Rosa Therapeutics (Inst); Roche/Genentech (Inst)
Patents, Royalties, Other Intellectual Property - Royalties from Wolters Kluwer (Pocket Oncology).
 
Jake June-Koo Lee
No Relationships to Disclose
 
Jennifer Zheng
No Relationships to Disclose
 
Linda Su Hyun Ahn
No Relationships to Disclose
 
Amanda Pupo
No Relationships to Disclose
 
Monica Nesselbush
Patents, Royalties, Other Intellectual Property - Patent pending related to cancer biomarkers.
 
Isabel Jabara
No Relationships to Disclose
 
Glenn Heller
No Relationships to Disclose
 
Kathryn C. Arbour
Consulting or Advisory Role - Amgen; AstraZeneca; Genzyme; Lilly; Novartis; Revolution Medicines; Sanofi
Research Funding - Genentech (Inst); Mirati Therapeutics (Inst); Revolution Medicines (Inst)
Travel, Accommodations, Expenses - Revolution Medicines
 
Fernando Costa Santini
Speakers' Bureau - AstraZeneca
 
Michael Offin
Honoraria - OncLive
Consulting or Advisory Role - American Society for Radiation Oncology; Jazz Pharmaceuticals; Novartis; Pfizer; Pfizer; Pfizer; PharmaMar; Targeted Oncology
Travel, Accommodations, Expenses - Bristol-Myers Squibb; Merck Sharp & Dohme
(OPTIONAL) Uncompensated Relationships - Mesothelioma Applied Research Foundation
 
Jamie E. Chaft
Consulting or Advisory Role - Arcus Biosciences; AstraZeneca/MedImmune; Bristol-Myers Squibb; Flame Biosciences; Genentech/Roche; Guardant Health; Janssen Oncology; Lilly; Merck; Sanofi/Regeneron
Research Funding - AstraZeneca/MedImmune (Inst); BeiGene (Inst); Bristol-Myers Squibb (Inst); Genentech/Roche (Inst); Merck (Inst); Novartis
(OPTIONAL) Uncompensated Relationships - AstraZeneca
 
Robert J. Young
No Relationships to Disclose
 
Gregory J. Riely
Research Funding - Lilly (Inst); Merck (Inst); Mirati Therapeutics (Inst); Novartis (Inst); Pfizer (Inst); Roche/Genentech (Inst); Takeda (Inst)
Patents, Royalties, Other Intellectual Property - Patent application submitted covering pulsatile use of erlotinib to treat or prevent brain metastases (Inst)
Travel, Accommodations, Expenses - Bayer; Merck
Other Relationship - Mirati Therapeutics; Pfizer; Roche/Genentech; Takeda
 
Mark G. Kris
Consulting or Advisory Role - AstraZeneca; BerGenBio; Daiichi Sankyo/Astra Zeneca; Merus; Mirati Therapeutics; Pfizer; Sanofi
Travel, Accommodations, Expenses - AstraZeneca; Genentech
 
Maximilian Diehn
Leadership - Foresight Diagnostics
Stock and Other Ownership Interests - CiberMed; Foresight Diagnostics; Gritstone Bio
Honoraria - Bristol-Myers Squibb Japan
Consulting or Advisory Role - AstraZeneca; Genentech; Gritstone Bio; Illumina; Novartis; Regeneron
Research Funding - AstraZeneca (Inst); Illumina (Inst)
Patents, Royalties, Other Intellectual Property - Patent filings on ctDNA detection assigned to Stanford University (Inst); Patent filings on tumor treatment resistance mechanisms assigned to Stanford University (Inst); Royalties from Foresight Diagnostics for patent licensing fees; Royalties from Roche for patent licensing fees
Travel, Accommodations, Expenses - Foresight Diagnostics; Regeneron
 
Adrienne Ann Boire
Consulting or Advisory Role - Apellis Pharmaceuticals
Patents, Royalties, Other Intellectual Property - Boire A and J Massagué, inventors. Sloan Kettering Institute, assignee. Modulating Permeability Of The Blood Cerebrospinal Fluid Barrier. United States Provisional Application No.: 62/258,044. November 20, 2015. (Inst); Boire A, Chen Q and J Massagué, inventors. Sloan Kettering Institute, assignee. Methods for Treating Brain Metastasis. United States 10413522, awarded September 17, 2019. (Inst); Boire A, inventor. Sloan Kettering Institute, assignee. Methods of Treating Leptomeningeal Metastasis. United States Provisional Application No.: 63/052,139. Jul 15, 2020 (Inst)
(OPTIONAL) Uncompensated Relationships - Evren Technologies