The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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Lenvatinib (len) plus pembrolizumab (pembro) in patients with advanced melanoma that progressed on anti–PD-(L)1 therapy: Over 4 years of follow-up from the phase 2 LEAP-004 study.

Ana Maria  Arance

Consulting or Advisory Role - BioNTech SE; BMS; MSD; Novartis; Pierre Fabre; Roche

Speakers' Bureau - BMS; MSD; Novartis; Pierre Fabre; Roche

Research Funding - BioNTech SE (Inst); BMS (Inst); MSD (Inst); Novartis (Inst); Pierre Fabre (Inst); Roche (Inst)

Travel, Accommodations, Expenses - BMS; MSD

Steven J.  O'Day

Employment - Agenus, Inc

Leadership - Agenus,Inc

Stock and Other Ownership Interests  - Agenus,Inc

Luis  de la Cruz-Merino

Consulting or Advisory Role - AstraZeneca; Bristol-Myers Squibb; Gilead Sciences; Incyte; MSD Oncology; Roche (Inst)

Research Funding - Celgene (Inst); Roche (Inst)

Travel, Accommodations, Expenses - Roche

Teresa M.  Petrella

Honoraria - Bristol-Myers Squibb/Celgene; Merck; Novartis; Pfizer; Sanofi

Consulting or Advisory Role - Bristol-Myers Squibb/Celgene; Merck; Novartis; Pfizer; Sanofi

Research Funding - Pfizer

Rahima  Jamal

Honoraria - Pfizer

Consulting or Advisory Role - Bristol-Myers Squibb; Medison

Research Funding - Alkermes (Inst); Astellas Pharma (Inst); AstraZeneca/MedImmune (Inst); BioNTech SE (Inst); Boehringer Ingelheim (Inst); Bristol-Myers Squibb (Inst); Evelo Biosciences (Inst); Immunocore (Inst); Iovance Biotherapeutics (Inst); Merck Sharp & Dohme (Inst); Novartis (Inst); Pacylex (Inst); Pfizer (Inst); Roche/Genentech (Inst); Surface Oncology (Inst); Takeda (Inst); VelosBio/Merck (Inst)

Lars  Ny

Consulting or Advisory Role - Bristol-Myers Squibb; GlaxoSmithKline; MSD; Novartis; Pierre Fabre; Sanofi; Zealth

Speakers' Bureau - Bristol-Myers Squibb/Celgene; GlaxoSmithKline; LEO Pharma; Miltenyi Biotec; MSD; Novartis; Pfizer

Research Funding - MSD (Inst); Syndax (Inst)

Ana  Carneiro

Honoraria - BMSi; Pierre Fabre

Consulting or Advisory Role - Baxter; Merck (Inst); MSD; Novartis; Pierre Fabre; Transgene (Inst)

Expert Testimony - BMSi; Merck

Alfonso  Berrocal-Jaime

Honoraria - Amgen; BMS; Merck Serono; MSD Oncology; Novartis; Pierre Fabre; Roche/Genentech; Sanofi

Consulting or Advisory Role - BMS; Merck; MSD Oncology; Novartis; Pierre Fabre; Roche/Genentech

Travel, Accommodations, Expenses - BMS; MSD

Ivan  Marquez-Rodas

Consulting or Advisory Role - Amgen; AstraZeneca; Bioncotech; Bristol-Myers Squibb; Immunocore; Incyte; Merck Serono; MSD; Novartis; Pierre Fabre; Regeneron; Roche; Sanofi; Sun Pharma

Travel, Accommodations, Expenses - Bioncotech; Bristol-Myers Squibb; MSD; Pierre Fabre; Roche; Sun Pharma

Anna  Spreafico

Honoraria - Immunocore

Consulting or Advisory Role - Bristol-Myers Squibb; Immunocore; Medison; Merck

Research Funding - Alentis Therapeutics (Inst); Alkermes (Inst); ALX Oncology (Inst); Amgen (Inst); Array BioPharma (Inst); AstraZeneca/MedImmune (Inst); Bayer (Inst); Bristol-Myers Squibb (Inst); Genentech (Inst); Gilead Sciences (Inst); GlaxoSmithKline (Inst); Incyte (Inst); Janssen Oncology (Inst); Merck (Inst); Novartis (Inst); Nubiyota (Inst); Pfizer (Inst); Replimune (Inst); Roche (Inst); Seagen (Inst); SERVIER (Inst); Surface Oncology (Inst); Symphogen (Inst); Treadwell Therapeutics (Inst)

Victoria  Atkinson

Honoraria - Bristol-Myers Squibb; Merck Sharp & Dohme; Nektar; Novartis; Pierre Fabre; Provectus Biopharmaceuticals; QBiotics

Consulting or Advisory Role - Bristol-Myers Squibb; Immunocore; Merck Serono; Merck Sharp & Dohme; Novartis; QBiotics

Speakers' Bureau - Bristol-Myers Squibb; Merck Serono; Merck Sharp & Dohme; Novartis; Roche/Genentech

Expert Testimony - Bristol-Myers Squibb/Celgene

Travel, Accommodations, Expenses - Bristol-Myers Squibb; Merck Sharp & Dohme; Novartis; OncoSec; Pierre Fabre

Fernanda Costa  Svedman

Employment - Npowermedicine INC (I)

Leadership - Npowermedicine INC (I)

Stock and Other Ownership Interests  - Npowermedicine INC (I)

Honoraria - Astellas Pharma (Inst); Bristol-Myers Squibb (Inst); Ipsen (Inst); Merck (Inst); Pfizer (Inst)

Consulting or Advisory Role - Precision medicine in Asia

Patents, Royalties, Other Intellectual Property - prognostic assay (I)

Travel, Accommodations, Expenses - Merck

Chinyere E  Okpara

Employment - Eisai

Kevin  Lawlor

Employment - Merck

Scott J.  Diede

Employment - Merck

Tobias  Neff

Employment - Merck

Georgina V.  Long

Honoraria - BMS; Pierre Fabre

Consulting or Advisory Role - Agenus; Amgen; Array BioPharma; AstraZeneca; Boehringer Ingelheim; Bristol Myers Squibb; Evaxion Biotech; Hexal; Highlight Therapeutics; Immunocore Ireland Limited; Innovent Biologics; IO Biotech; Merck Sharp & Dohme; Novartis; OncoSec; PHMR; Pierre Fabre; Regeneron