The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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A prognostic model based on selected cell state and cellular community scores in patients with advanced melanoma treated with immune checkpoint inhibitors (Ecotype-ICI score) as a predictor of ICI immunotherapeutic benefits.
 
Ahmad A. Tarhini
Consulting or Advisory Role - AstraZeneca; Bayer; BioNTech; Bristol-Myers Squibb; Clinigen Group; ConcertAI; Eisai; Genentech/Roche; Instil Bio; Merck; Nested; Novartis; Partner Therapeutics; Sanofi/Regeneron
Research Funding - Acrotech Biopharma (Inst); Agenus (Inst); Agenus (Inst); Bristol-Myers Squibb (Inst); Clinigen Group (Inst); Genentech/Roche (Inst); InflaRx (Inst); Merck (Inst); OncoSec (Inst); Pfizer (Inst); Sanofi/Regeneron (Inst); Scholar Rock (Inst)
 
Tingyi Li
No Relationships to Disclose
 
Sandra J. Lee
No Relationships to Disclose
 
Islam Eljilany
No Relationships to Disclose
 
William LaFramboise
No Relationships to Disclose
 
F. Stephen Hodi
Employment - Dana-Farber Cancer Institute
Leadership - Bicara Therapeutics
Stock and Other Ownership Interests - Apricity Health; Bicara Therapeutics; Pionyr; Torque
Consulting or Advisory Role - AstraZeneca; Bioentre; Bristol-Myers Squibb; Catalym; Checkpoint THerapeutics; Compass Therapeutics; Corner Therapeutics; Curis; Genentech/Roche; Gossamer Bio; Immunocore; Iovance Biotherapeutics; Kairos Therapeutics; Merck Sharp & Dohme; Novartis; Rheos Medicines; Surface Oncology; Zumutor Biologics
Research Funding - bristol-myers squibb (Inst); Genentech/Roche (Inst); Merck Sharp & Dohme (Inst); novartis (Inst)
Patents, Royalties, Other Intellectual Property - Angiopoietin-2 Biomarkers Predictive of Anti-immune checkpoint response (Inst); Compositions and Methods for Identification, Assessment, Prevention, and Treatment of Melanoma using PD-L1 Isoforms; Methods of Using Pembrolizumab and Trebananib (Inst); patent pending as per institutional policy; patent pending royalties received on MICA related disorders application to institution per institutional IP policy
Travel, Accommodations, Expenses - Bristol-Myers Squibb; Novartis
Other Relationship - Bristol-Myers Squibb; Genentech/Roche
 
Martin McCarter
No Relationships to Disclose
 
Abdul Rafeh Naqash
Honoraria - NGM Biopharmaceuticals
Consulting or Advisory Role - foundation me
Travel, Accommodations, Expenses - American Society for Radiation Oncology; ASCO; Binacea; Foundation Medicine; Jazz Pharmaceuticals (Inst); Society for Immunotherapy of Cancer
 
Howard Colman
Consulting or Advisory Role - Adastra Pharmaceuticals; Best Doctors, Inc; Bristol-Myers Squibb; Novocure; Orbus Therapeutics; PPD/Chimerix; Regeneron
Research Funding - Abbvie (Inst); Array BioPharma (Inst); Bayer (Inst); BeiGene (Inst); Bristol-Myers Squibb (Inst); DNAtrix (Inst); Erasca, Inc (Inst); FORMA Therapeutics (Inst); Global Coalition for Adaptive Research (Inst); Kadmon (Inst); Merck (Inst); Nuvation Bio (Inst); Orbus Therapeutics (Inst); Samus Therapeutics (Inst); Sumitomo Dainippon Pharma Oncology (Inst)
Travel, Accommodations, Expenses - Bayer; FORMA Therapeutics; Karyopharm Therapeutics; Orbus Therapeutics; Regeneron
 
Margaret E Gatti-Mays
Honoraria - Oncology Learning Network
Consulting or Advisory Role - GE HealthCare; SeaGen
 
Aakrosh Ratan
No Relationships to Disclose
 
Susanne M. Arnold
Consulting or Advisory Role - Penn State Cancer Institute
Research Funding - Abbvie (Inst); AstraZeneca (Inst); BeiGene (Inst); Bicara Therapeutics, Inc (Inst); Ellipses Pharma (Inst); Exelixis (Inst); Fortrea Inc (Inst); Gilead Sciences (Inst); Incyte (Inst); Kinnate Biopharma (Inst); Kura Oncology (Inst); Lilly (Inst); Lisata Therapeutics, Inc. (Inst); Merck Sharp & Dohme (Inst); National Cancer Institute (Inst); Ohio State University (Inst); Syneos Health (Inst)
 
Igor Puzanov
Stock and Other Ownership Interests - Compugen; IDEAYA Biosciences; IDEAYA Biosciences (I)
Consulting or Advisory Role - Iovance Biotherapeutics; Nouscom
Research Funding - NIH/NCI (Inst)
 
Michelle L. Churchman
No Relationships to Disclose
 
William S. Dalton
Employment - M2Gen
Stock and Other Ownership Interests - M2Gen
Patents, Royalties, Other Intellectual Property - I am the inventor of 11 patents owned by the Moffitt Cancer Center. The patents are in two areas: 1. new target discoveries in cancers 2. new information systems for health and molecular data
 
George J. Weiner
No Relationships to Disclose
 
Howard Streicher
No Relationships to Disclose
 
Walter J Storkus
No Relationships to Disclose
 
John M. Kirkwood
Honoraria - Bristol-Myers Squibb
Consulting or Advisory Role - Amgen; Ankyra Therapeutics; Applied Clinical Intelligence; AXIO Research; Becker Pharmaceutical Consulting; Bristol Myers Squibb; Cancer Network; Cancer Study Group; Checkmate Pharmaceuticals; CytomX Therapeutics; DermTech; Fenix Group International; Harbour BioMed; Immunocore; iOnctura; Iovance Biotherapeutics; IQVIA; Istari Oncology; Jazz Pharmaceuticals; Lytix Biopharma; Magnolia Innovation; Merck; Natera; Novartis; OncoCyte; OncoSec; PATHAI; Pfizer; Piper Sandler; PyrOjas Corporation; Regeneron; Replimune; Scopus BioPharma; SR One Capital Management; Takeda; Valar Labs
Research Funding - Amgen (Inst); Bristol-Myers Squibb (Inst); Checkmate Pharmaceuticals (Inst); Harbour BioMed (Inst); Immunocore (Inst); Immvira (Inst); Iovance Biotherapeutics (Inst); Lion Biotechnologies (Inst); Novartis (Inst); Takeda (Inst); Verastem (Inst)
Travel, Accommodations, Expenses - Ankyra Therapeutics; Bristol-Myers Squibb; Checkmate Pharmaceuticals; Iovance Biotherapeutics; Regeneron
 
Xuefeng Wang
No Relationships to Disclose