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A phase 1/1b study of the IL-2 prodrug WTX-124 in patients with locally advanced or metastatic solid tumors after checkpoint inhibitor therapy: Initial results of the combination dose escalation with pembrolizumab. |
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Honoraria - Caris Life Sciences; Daiichi Sankyo/Lilly; TGen |
Consulting or Advisory Role - Adagene; Amunix; Boxer Capitol; Bristol Myers Squibb Foundation; Genome Insight; Imaging Endpoints; Incyte; IQvia; Novotech; Oberland Capital; Red Arrow Therapeutics; Thirona Biosciences; Werewolf Therapeutics (Inst) |
Speakers' Bureau - Caris Life Sciences; Castle Biosciences; Immunocore |
Research Funding - Adaptimmune (Inst); Agenus (Inst); Alpine Immune Sciences (Inst); Amgen (Inst); BioEclipse Therapeutics (Inst); Fate Therapeutics (Inst); Fujifilm (Inst); Genentech (Inst); IDEAYA Biosciences (Inst); ImmuneSensor Therapeutics (Inst); Iovance Biotherapeutics (Inst); Istari Oncology (Inst); Nektar (Inst); Novocure (Inst); Repertoire Immune Medicines (Inst); Rubius Therapeutics (Inst); Senhwa Biosciences (Inst); Simcha Therapeutics (Inst); Storm Therapeutics (Inst); Synthorx (Inst); T-Scan Therapeutics (Inst); Trishula Therapeutics (Inst); University of Arizona (Inst); Werewolf Therapeutics (Inst); Y-mAbs Therapeutics (Inst) |
Other Relationship - Caris Life Sciences |
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Stock and Other Ownership Interests - crispr therapeutics |
Consulting or Advisory Role - AstraZeneca |
Research Funding - Alphageneron; Bayer; Pfizer |
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Ildefonso Rodriguez Rivera |
Employment - Next Oncology; Texas Oncology |
Stock and Other Ownership Interests - Pfizer |
Consulting or Advisory Role - Syneos Health |
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Honoraria - Clinigen Group; Sanofi |
Consulting or Advisory Role - Merck |
Research Funding - Bristol-Myers Squibb (Inst); Clinigen Group (Inst) |
Patents, Royalties, Other Intellectual Property - Biomarkers for OX40 response (Inst) |
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Stock and Other Ownership Interests - Compugen; IDEAYA Biosciences; IDEAYA Biosciences (I) |
Consulting or Advisory Role - Iovance Biotherapeutics; Nouscom |
Research Funding - NIH/NCI (Inst) |
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Honoraria - Apexigen; Aveo; Iovance Biotherapeutics; Jazz Pharmaceuticals |
Consulting or Advisory Role - Apexigen; Iovance Biotherapeutics; Jazz Pharmaceuticals |
Research Funding - Werewolf Pharma (Inst) |
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Consulting or Advisory Role - AstraZeneca; Bayer; Bristol-Myers Squibb; Calithera Biosciences; Eisai; EMD Serono; Exelixis; Exelixis; Genomic Health; Janssen; Nektar; Pfizer; Sanofi; SeaGen |
Research Funding - Advanced Accelerator Applications (Inst); AstraZeneca (Inst); Bayer (Inst); Bristol-Myers Squibb (Inst); Exelixis (Inst); Genentech/Roche (Inst); Genome & Company (Inst); Incyte (Inst); Merck (Inst); Nektar (Inst); NiKang Therapeutics (Inst); Peloton Therapeutics (Inst); Pfizer (Inst); Seagen (Inst); Tricon Pharmaceuticals (Inst); Xencor (Inst) |
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Employment - Werewolf Therapeutics |
Stock and Other Ownership Interests - Werewolf Therapeutics |
Patents, Royalties, Other Intellectual Property - On patent application related to Werewolf Therapeutics intellectual property (Inst) |
Travel, Accommodations, Expenses - Werewolf Therapeutics |
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No Relationships to Disclose |
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Employment - Werewolf Therapeutics |
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No Relationships to Disclose |
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Employment - Bicara Therapeutics (I); Werewolf Therapeutics |
Stock and Other Ownership Interests - Novartis; Regeneron; Werewolf Therapeutics |
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Kulandayan K. Subramanian |
Employment - Daiichi Sankyo; United Health Group (I); Werewolf Therapeutics |
Stock and Other Ownership Interests - Avidity Biosciences; CureVac; CureVac; Dynavax Technologies; Gilead Sciences; Intellia Therapeutics; MindMed; Moderna Therapeutics; Novavax; UnitedHealthcare (I); Werewolf Therapeutics |
Patents, Royalties, Other Intellectual Property - Patent 059034-US-PCT Dosage regimes for anti-CD73 and anti-ENTPD2 antibodies and uses of thereof; Patent PCT/US23/78580 NKG2D fusion protein cancer therapy |
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Oliver Schönborn-Kellenberger |
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Employment - Takeda; Werewolf Therapeutics |
Stock and Other Ownership Interests - Werewolf Therapeutics |
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Employment - Werewolf Therapeutics |
Leadership - Werewolf Therapeutics |
Stock and Other Ownership Interests - Werewolf Therapeutics |
Consulting or Advisory Role - C4 Therapeutics; Hookipa Biotech |
Patents, Royalties, Other Intellectual Property - I am listed on several patents from Werewolf Therapeutics around the clinical use of the INDUKINE molecules, as well as from my previous employment with Novartis Pharmaceuticals involving CAR-T therapy |