The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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IAM1363-01: A phase 1/1b study of a selective and brain-penetrant HER2 inhibitor for HER2-driven solid tumors.
 
Alex A Adjei
Consulting or Advisory Role - EMD Serono; Janssen; Mirati Therapeutics; Swiss Rockets; Zai Lab
Research Funding - Bayer Schering Pharma (Inst); I-Mab (Inst); Jacobio (Inst); Kura Oncology (Inst); Merck KGaA (Inst); Tesaro (Inst); Zai Lab (Inst)
(OPTIONAL) Uncompensated Relationships - Merck KGaA; Swiss Rockets; Zai Lab
 
Kwok-Kin Wong
Stock and Other Ownership Interests - Array BioPharma; Bluebird Bio; G1 Therapeutics
Honoraria - AstraZeneca; Bristol-Myers Squibb; Genocea Biosciences; Janssen Oncology; Merck; Mirati Therapeutics; Novartis; Pfizer
Research Funding - Blueprint Medicines (Inst); BridgeBio Pharma (Inst); Bristol Myers Squibb Foundation (Inst); Delfi Diagnostics (Inst); Janssen Oncology (Inst); Janssen Oncology (Inst); Mirati Therapeutics (Inst); Pfizer (Inst); Takeda (Inst); Tango Therapeutics (Inst)
Travel, Accommodations, Expenses - Takeda
 
Maria Koehler
Employment - Bicycle Therapeutics; Repare Therapeutics
Stock and Other Ownership Interests - Ikena Oncology; Pfizer; Repare Therapeutics
Consulting or Advisory Role - Orum Therapeutics; Urogen Pharma
 
Alexander I. Spira
Leadership - Next Oncology (Inst)
Stock and Other Ownership Interests - Lilly
Honoraria - Amgen; AstraZeneca/MedImmune; Bayer; Bristol-Myers Squibb; CytomX Therapeutics; Janssen Oncology; Merck; Novartis; Takeda
Consulting or Advisory Role - Amgen; Array BioPharma (Inst); AstraZeneca/MedImmune (Inst); AstraZeneca/MedImmune (Inst); Black Diamond Therapeutics; Blueprint Medicines (Inst); Bristol-Myers Squibb (Inst); Daiichi Sankyo/Astra Zeneca; Gritstone Bio; Gritstone Bio; incyte; Janssen Research & Development; Jazz Pharmaceuticals; Lilly; Merck (Inst); Mersana; Mirati Therapeutics; Novartis; Regeneron; Sanofi; Sanofi; Takeda
Research Funding - Abbvie (Inst); ADC Therapeutics (Inst); ADC Therapeutics (Inst); Alkermes (Inst); Amgen (Inst); Arch Therapeutics (Inst); ArriVent Biopharma (Inst); Astellas Pharma (Inst); Astex Pharmaceuticals (Inst); AstraZeneca (Inst); Black Diamond Therapeutics (Inst); Blueprint Medicines (Inst); BluPrint Oncology (Inst); Boehringer Ingelheim (Inst); Bristol-Myers Squibb (Inst); CytomX Therapeutics (Inst); Daiichi Sankyo (Inst); Gritstone Bio (Inst); Ignyta (Inst); Incyte (Inst); Janssen Oncology (Inst); LAM Therapeutics; Loxo (Inst); Loxo (Inst); Macrogenics (Inst); Medikine (Inst); MedImmune (Inst); mersana (Inst); Mirati Therapeutics (Inst); nalo therapeutics (Inst); Novartis (Inst); Plexxikon (Inst); Regeneron; Revolution Medicines (Inst); Revolution Medicines (Inst); Roche (Inst); Rubius Therapeutics (Inst); Scorpion Therapeutics (Inst); Synthekine (Inst); Synthekine (Inst); Takeda (Inst)
 
Katherine L. Jameson
Employment - Nurix
Stock and Other Ownership Interests - JJ Innovative Medicine; Nanobiotix Therapeutics; Nurix
Consulting or Advisory Role - Iambic Therapeutics; JW Consulting; KLJameson Consulting; Lyell Therapeutics; Opna Therapeutics; Orbus Therapeutics; Rgenta; Storm Therapeutics
Patents, Royalties, Other Intellectual Property - Jameson, K.L. and Khavari, P.A, “Scaffold-Kinase Interaction Blockades and Uses Thereof in Treating Cancer,” International Patent Authority, Application Serial No. PCT/US2012/032375 (filed 04/07/2012).
 
Deb Chapman
Employment - Pyramid Biosciences, Inc.
Consulting or Advisory Role - Iambic Therapeutics
 
Jacqueline M. Walling
Leadership - Entos AI; Opna; Orbus Therapeutics; Plexxikon; Propella Therapeutics
Stock and Other Ownership Interests - Amgen
Consulting or Advisory Role - Ambagon Therapeutics; Aminex; Black Diamond Therapeutics; Cumulus Oncology; Entos AI; Flag Therapeutics; Harpoon Therapeutics; Janux Therapeutics; Lyell Immunopharma; Myovant Sciences; Nurix; Nuvation Bio; Opna Bio; Orbus Therapeutics; Oryzon Genomics; Plexxikon; Propella Therapeutics; Rgenta; Rhizen Pharmaceuticals; Storm Therapeutics
 
Neil C. Josephson
Employment - Iambic Therapetics; Zymeworks
Leadership - Iambic Therapeutics; Zymeworks
Stock and Other Ownership Interests - Zymeworks
 
Zhongdong Huang
Employment - Iambic Therapeutics, Inc.
Stock and Other Ownership Interests - Iambic Therapeutics, Inc.