The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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A first-in-human, phase 1, dose escalation study of SGR-2921 as monotherapy in patients with relapsed/refractory acute myeloid leukemia or myelodysplastic syndrome.
 
Daniel Weiss
Employment - Schrodinger
Stock and Other Ownership Interests - Schrodinger
Consulting or Advisory Role - Schrodinger
 
Courtney Denton Dinardo
Honoraria - Abbvie; Astellas Pharma; Bristol Myers Squibb Foundation; Cleave Biosciences; Foghorn Therapeutics; Genentech/Abbvie; Genmab; Gilead Sciences; GlaxoSmithKline; Jazz Pharmaceuticals; Novartis; Schrodinger; SERVIER
Consulting or Advisory Role - Abbvie; Agios; Celgene; GlaxoSmithKline
Research Funding - Abbvie; Astex Pharmaceuticals; Celgene; Cleave Therapeutics; Foghorn Therapeutics; Immune-Onc Therapeutics; Jazz Pharmaceuticals; Loxo/Lilly; SERVIER
 
Stephen Anthony Strickland
Consulting or Advisory Role - Abbvie; BerGenBio; Genentech Mypath; Novartis; Senti Biosciences
 
Barry Skikne
Consulting or Advisory Role - Schrodinger
 
Amer Methqal Zeidan
Honoraria - Abbvie; Agios; Akeso Biopharma; ALX Oncology; Amgen; Astellas Pharma; BeiGene; BioCryst; Boehringer Ingelheim; Bristol-Myers Squibb; Celgene; Chiesi; Daiichi Sankyo; Epizyme; Faron Pharmaceuticals; Genentech; Geron; Gilead Sciences; Glycomimetics; Hikma Pharmaceuticals; Janssen; Karyopharm Therapeutics; Keros Therapeutics; Kura Oncology; Kyowa Kirin International; lava therapeutics; Mendus; Notable Labs; Novartis; Orum Therapeutics; Otsuka; Pfizer; Regeneron; Rigel; Schrodinger; SERVIER; Shattuck Labs; Sumitomo Pharma Oncology; Syndax; Syros Pharmaceuticals; Taiho Pharmaceutical; Takeda; Treadwell Therapeutics; Vincerx Pharma; Zentalis
Consulting or Advisory Role - Abbvie; Agios; Akeso Biopharma; ALX Oncology; Amgen; Astellas Pharma; Astex Pharmaceuticals; BeiGene; BioCryst; Boehringer Ingelheim; Bristol-Myers Squibb; Celgene; Chiesi; Daiichi Sankyo; Epizyme; Faron Pharmaceuticals; Genentech; Geron; Gilead Sciences; Glycomimetics; Hikma Pharmaceuticals; Janssen; Karyopharm Therapeutics; Keros Therapeutics; Kura Oncology; Kyowa Kirin International; lava therapeutics; Mendus; Notable Labs; Novartis; Orum Therapeutics; Otsuka; Pfizer; Regeneron; Rigel; Schrodinger; SERVIER; Shattuck Labs; Sumitomo Pharma Oncology; Syndax; Syros Pharmaceuticals; Taiho Pharmaceutical; Takeda; Treadwell Therapeutics; Vincerx Pharma; Zentalis
Research Funding - Abbvie (Inst); Amgen; Astex Pharmaceuticals (Inst); Bristol-Myers Squibb (Inst); Celgene (Inst); Geron; Kura Oncology; Novartis (Inst); Otsuka; Shattuck Labs; Syros Pharmaceuticals; Takeda (Inst)
 
Elie A. Traer
Leadership - Abbvie; Astellas Pharma; Daiichi Sankyo; Rigel; SERVIER
Consulting or Advisory Role - Abbvie
Speakers' Bureau - Schrodinger
Research Funding - AstraZeneca; Incyte; Prelude Therapeutics
 
Hetty E Carraway
Honoraria - BMSi; Jazz Pharmaceuticals; Novartis
Consulting or Advisory Role - BMS; Daiichi Sankyo/Lilly
Speakers' Bureau - Agios; BMSi; Jazz Pharmaceuticals
Research Funding - Celgene
Travel, Accommodations, Expenses - Jazz Pharmaceuticals; Novartis
Other Relationship - Syndax
 
Stanley R. Frankel
Employment - Cytovia Therapeutics
Leadership - Myeloid Therapeutics; Precision Biosciences
Stock and Other Ownership Interests - Adagene; Precision Biosciences; Sutro Biopharma
Honoraria - Chimeric Therapeutics; OPKO Health
Consulting or Advisory Role - Adagene; AstraZeneca; Autolus Therapeutics; Cargo Therapeutics; Deka Bioscience; Harpoon therapeutics; Immunai; Myeloid Therapeutics; Precision Biosciences; Sutro Biopharma
 
Jacky Wang
Employment - Schrodinger
 
Steven Robert Pirie-Shepherd
Employment - Schrodinger
Stock and Other Ownership Interests - Schrodinger
 
Joseph R. Piccotti
Employment - Schrodinger
Stock and Other Ownership Interests - Schrodinger
 
Duncan Hamish Wright
Employment - Schrodinger
Stock and Other Ownership Interests - Schrodinger
 
Karen Akinsanya
Employment - Schrodinger
Stock and Other Ownership Interests - Schrodinger