The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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Rates of pathologic complete response (pCR) after datopotamab deruxtecan (Dato) plus durvalumab (Durva) in the neoadjuvant setting: Results from the I-SPY2.2 trial.
 
Rebecca Arielle Shatsky
Honoraria - Curio Science; IDEOlogy Health; OncLive/MJH Life Sciences; Vaniam Group
Consulting or Advisory Role - AstraZeneca; Stemline Therapeutics; The Dedham Group
Speakers' Bureau - Gilead Sciences
Research Funding - Genentech (Inst); OBI Pharma (Inst); Phoenix Molecular Designs (Inst); QuantumLeap Health (Inst)
 
Meghna S. Trivedi
Research Funding - AstraZeneca (Inst); Gilead Sciences (Inst); Lilly (Inst); Merck (Inst); Novartis (Inst); Phoenix Molecular Designs (Inst); Regeneron (Inst)
 
Coral Oghenerukevwe Omene
Honoraria - Jazz Pharmaceuticals
 
Kevin Kalinsky
Employment - EQRx (I); GRAIL (I)
Stock and Other Ownership Interests - EQRx (I); GRAIL (I)
Consulting or Advisory Role - 4D Pharma; AstraZeneca; Cullinan Oncology; Cullinan Oncology; Daiichi Sankyo/Astra Zeneca; eFFECTOR Therapeutics; Genentech/Roche; immunomedics; Lilly; Menarini Silicon Biosystems; Merck; mersana; Myovant Sciences; Novartis; Oncosec; Prelude Therapeutics; Puma Biotechnology; RayzeBio; RayzeBio; Seagen; Takeda
Research Funding - Ascentage Pharma (Inst); AstraZeneca (Inst); Daichi Sankyo (Inst); Genentech/Roche (Inst); Lilly (Inst); Novartis (Inst); Seagen (Inst)
Other Relationship - Genentech; Immunomedics
 
Evanthia T. Roussos Torres
Consulting or Advisory Role - Synaptical
 
Brittani Thomas
No Relationships to Disclose
 
Amy Sanford
No Relationships to Disclose
 
Kathy S. Albain
Honoraria - Encore Medical Education
Research Funding - Quantum Leap Healthcare Collaborative (Inst); Seagen (Inst)
Other Relationship - Seagen
 
Amy Sanders Clark
Honoraria - Siemens
Consulting or Advisory Role - Novartis
Research Funding - Lilly (Inst); Novartis (Inst); Seagen (Inst)
 
Carla Isadora Falkson
Honoraria - Curio Science
Consulting or Advisory Role - Agendia; bioTheranostics
Speakers' Bureau - OncLive/MJH Life Sciences
Research Funding - Lilly (Inst); Oncolytics (Inst); QuantumLeap Health (Inst)
 
Claudine Isaacs
Honoraria - Pfizer; Pfizer
Consulting or Advisory Role - AstraZeneca/MedImmune; Gilead Sciences; Ion Solutions; Novartis; Pfizer; Puma Biotechnology; Seagen
Research Funding - AstraZeneca (Inst); Bristol-Myers Squibb/Celgene (Inst); Genentech/Roche (Inst); GlaxoSmithKline (Inst); Merck (Inst); Novartis (Inst); Pfizer (Inst); Seagen (Inst); Tesaro (Inst)
Patents, Royalties, Other Intellectual Property - Elsevier - Editor of Book; McGraw Hill Publishing; UpToDate - Wolters Kluwer - Author of chapters
Travel, Accommodations, Expenses - Pfizer
Other Relationship - Curio/Vaniam Group; Medscape; MJH/PER; Side-Out Foundation
 
Alexandra Thomas
Stock and Other Ownership Interests - Bristol-Myers Squibb; Doximity; Gilead Sciences; Johnson & Johnson (I); Pfizer
Consulting or Advisory Role - AstraZeneca
Research Funding - Merck (Inst); Sanofi (Inst)
Patents, Royalties, Other Intellectual Property - Up-to-Date Royalties (I)
 
Jennifer Tseng
Research Funding - Intuitive Surgical
Travel, Accommodations, Expenses - Elucent Medical; Intuitive Surgical; Stryker
 
Laura van 't Veer
Employment - Agendia
Stock and Other Ownership Interests - Agendia; Exai Bio
 
Hope S. Rugo
Consulting or Advisory Role - Daiichi Sankyo; Eisai; Mylan; Napo Pharmaceuticals; Puma Biotechnology
Research Funding - Astellas Pharma (Inst); AstraZeneca (Inst); Daiichi Sankyo (Inst); Gilead Sciences (Inst); GlaxoSmithKline (Inst); Hoffmann-La Roche AG/Genentech, Inc (Inst); Lilly (Inst); Merck (Inst); Novartis (Inst); OBI Pharma (Inst); Pfizer (Inst); Stemline Therapeutics (Inst); Taiho Oncology (Inst); Veru (Inst)
 
Nola Hylton
Research Funding - Siemens Healthineers (Inst)
 
Douglas Yee
Honoraria - Boehringer Ingelheim
Consulting or Advisory Role - Martell diagnostic
Research Funding - Boehringer Ingelheim
 
Christina Yau
Patents, Royalties, Other Intellectual Property - U.S. Provisional Application No. 63/314,065 (Inst); U.S. Provisional Application No. 63/341,579 (Inst)
 
Laura Esserman
Consulting or Advisory Role - Blue Cross Blue Shield Association
Research Funding - Moderna Therapeutics (Inst)
Travel, Accommodations, Expenses - Blue Cross Blue Shield Association
(OPTIONAL) Uncompensated Relationships - Quantum Leap Healthcare Collaborative