The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
Open Payments is a public database containing information reported by companies about payments made to US-licensed physicians (Open Payments)
EVEREST-2: A seamless phase 1/2 study of A2B694, a logic-gated Tmod chimeric antigen receptor T-cell (CAR T) therapy, in patients with pancreatic cancer (PANC) or other mesothelin (MSLN)-expressing solid tumors and human leukocyte antigen (HLA)–A*02 loss of heterozygosity (LOH).
 
Kristen Spencer
Honoraria - Dava Oncology
Consulting or Advisory Role - AstraZeneca; AstraZeneca; Caris Life Sciences; Exelixis; Genentech/Roche
Speakers' Bureau - American Cancer Society
Research Funding - Winn CDA
Travel, Accommodations, Expenses - ASCO; Cholangiocarcinoma Foundation
 
Salman Punekar
Research Funding - A2 Biotherapeutics (Inst); Affini-T Therapeutics (Inst); Amgen (Inst); Astellas Pharma (Inst); Constellation Pharmaceuticals (Inst); NCI (Inst); Neogene Therapeutics (Inst); Prelude Therapeutics (Inst); Revolution Medicines (Inst); Simcere (Inst); Tango Therapeutics (Inst); VITRAC Therapeutics (Inst)
 
Patrick Grierson
Employment - Walgreens (I)
Honoraria - AstraZeneca
Consulting or Advisory Role - AstraZeneca
Patents, Royalties, Other Intellectual Property - Compositions and Methods for the Treatment of Pancreatic Cancer
 
Jasmine Mitchell
No Relationships to Disclose
 
Yi Lin
Consulting or Advisory Role - Adicet Bio (Inst); Bristol-Myers Squibb (Inst); Caribou Biosciences (Inst); Chimeric Therapeutics (Inst); Fosun Kite (Inst); Genentech (Inst); Janssen Oncology (Inst); Kite/Gilead (Inst); Nektar (Inst); NexImmune (Inst); Pfizer (Inst); Regeneron (Inst); Sanofi (Inst); Vineti (Inst)
Research Funding - Bristol-Myers Squibb (Inst); Janssen Oncology (Inst)
 
Tiago Biachi de Castria
Consulting or Advisory Role - AstraZeneca; Bayer; Moderna Therapeutics; MSD Oncology
Speakers' Bureau - AstraZeneca; Bristol Myers Squibb Foundation; Lilly; MSD; Roche; SERVIER
Travel, Accommodations, Expenses - A2 Biotherapeutics; Ipsen
 
David Zhen
Consulting or Advisory Role - Boehringer Ingelheim; Bristol Myers Squibb; Exelixis; Jazz Pharmaceuticals; Legend Biotech; Medigene
Research Funding - A2 Biotherapeutics (Inst); AstraZeneca (Inst); Bayer (Inst); Bristol Myers Squibb (Inst); Cornerstone Pharmaceuticals (Inst); Daiichi Sankyo/Astra Zeneca (Inst); Genentech (Inst); Legend Biotech (Inst); Lilly (Inst); Medigene (Inst); Merck (Inst); Pfizer (Inst)
 
Peter Vu
No Relationships to Disclose
 
Maria Pia Morelli
No Relationships to Disclose
 
Madappa Kundranda
Consulting or Advisory Role - AstraZeneca; Bayer; Boston Scientific; BPG Bio; Bristol-Myers Squibb; Genomic Health; STERIS
Research Funding - Bayer (Inst); Celgene; Chronix Biomedical (Inst)
 
Oliver Dorigo
Honoraria - Blueprint Medicines
Consulting or Advisory Role - AstraZeneca; Clovis Oncology; GlaxoSmithKline; IMV; Merck; PSI CRO Deutschland; R-Pharm
Speakers' Bureau - Immunogen
Research Funding - AstraZeneca (Inst); BioEclipse Therapeutics (Inst); EMD Serono (Inst); Genentech (Inst); IMV (Inst); Millennium (Inst); Novartis (Inst); PharmaMar (Inst)
 
David Maloney
Stock and Other Ownership Interests - A2 Biotherapeutics
Honoraria - A2 Biotherapeutics; Bristol-Myers Squibb/Celgene; Genentech/Roche; Gilead Sciences; Kite, a Gilead company; Lyell Immunopharma; Novartis; Umoja Biopharma
Consulting or Advisory Role - A2 Biotherapeutics; Celgene/Bristol-Myers Squibb; Genentech; NAVAN Technologies
Research Funding - Celgene (Inst); Juno Therapeutics (Inst); Kite, a Gilead company (Inst)
Patents, Royalties, Other Intellectual Property - Inventor on 4 provisional patents.
 
Jeffrey Ward
Employment - Millipore (I); Pfizer (I)
Consulting or Advisory Role - AstraZeneca; Guidepoint Inc; Jazz Pharmaceuticals; Novocure; Obsidian Therapeutics; Takeda
Research Funding - Asher Biotherapeutics (Inst); AstraZeneca (Inst); Genmab (Inst); Harpoon therapeutics (Inst); Instil Bio (Inst); Novocure (Inst); Pfizer (Inst); Roche/Genentech (Inst); WindMIL (Inst)
Travel, Accommodations, Expenses - Halozyme; Novocure
 
Cathy Eng
Consulting or Advisory Role - Abbvie; Amgen (I); California Institute for Regenerative Medicine (CIRM) (I); Hookipa Biotech; IgM Biosciences (I); Merck Serono; Pfizer; Seagen; Taiho Oncology (I); Takeda
Research Funding - Gritstone Bio (Inst); Hutchison MediPharma (Inst); Janssen Oncology (Inst); Merck (Inst); Pfizer (Inst); Sumitomo Dainippon Pharma Oncology (Inst)
Travel, Accommodations, Expenses - Takeda
 
Marcela Maus
Leadership - 2seventy bio
Stock and Other Ownership Interests - 2seventy bio; Century Therapeutics; TCR2 Therapeutics
Consulting or Advisory Role - Adaptimmune; Agenus; arcellx; Astellas Pharma; AstraZeneca; Atara Biotherapeutics; Bayer; Bristol-Myers Squibb; Cabaletta Bio; crispr therapeutics; GlaxoSmithKline; In8bio; Intellia Therapeutics; Kite, a Gilead Company; MicroMedicine; Novartis; Sanofi; TCR2 Therapeutics; Tmunity Therapeutics, Inc.; Torque; windmil
Research Funding - CRISPR Therapeutics (Inst); Kite, a Gilead Company (Inst); Novartis (Inst); Servier (Inst)
Patents, Royalties, Other Intellectual Property - Inventor on patents held by Massachusetts General Hospital/Partners Health care; all related to CAR T cells and/or gene therapy; Inventor on patents held by U. Pennsylvania with and without Novartis
 
Diane Simeone
Leadership - Immodulon; Immunovia
Stock and Other Ownership Interests - Longevity Life Advisors
Honoraria - Pfizer
Consulting or Advisory Role - FibroGen
Research Funding - Biological Dynamics; Clearnote Health; Immunovia; Micronoma
Patents, Royalties, Other Intellectual Property - small royalties for my patent on pancreatic cancer stem cells also I receive an annual royalty for a textbook I edited Greenfields Textbook of Surgery
 
John Welch
Employment - A2 Biotherapeutics
Stock and Other Ownership Interests - A2 Biotherapeutics
Consulting or Advisory Role - Agios; Archer
Research Funding - Janssen Oncology (Inst); Notable Labs (Inst)
 
Julian Molina
No Relationships to Disclose
 
William Go
Employment - A2 Biotherapeutics
Leadership - A2 Biotherapeutics
Stock and Other Ownership Interests - A2 Biotherapeutics
Travel, Accommodations, Expenses - A2 Biotherapeutics
 
Joel Hecht
Stock and Other Ownership Interests - Actym Therapeutics; Rafael Pharmaceuticals; Trumvira
Consulting or Advisory Role - Astellas Pharma; BeiGene; Bristol-Myers Squibb/Medarex; Galvanize Therapeutics; IgM Biosciences; MBQ Pharma; Taiho Pharmaceutical
Research Funding - A2 Biotherapeutics (Inst); Affini-T Therapeutics (Inst); Agenus (Inst); Amgen (Inst); Bold Therapeutics (Inst); Camurus (Inst); Cardiff Oncology (Inst); CG Pharmaceuticals (Inst); Crinetics Pharmaceuticals (Inst); Exelixis (Inst); Gilead Sciences (Inst); Gritstone Bio (Inst); Janssen Oncology (Inst); Lyell Immunopharma (Inst); Merck (Inst); Mirati Therapeutics (Inst); Neogene Therapeutics (Inst); NGM Biopharmaceuticals (Inst); Regeneron (Inst); Revolution Medicines (Inst); Seagen (Inst); Tizona Therapeutics, Inc. (Inst); Tizona Therapeutics, Inc. (Inst); Xilio Therapeutics (Inst)