The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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Safety and biomarker assessment of ST316, a novel peptide antagonist of ß-catenin, in patients with advanced solid tumors.
 
Anthony El-Khoueiry
Honoraria - Agenus; AstraZeneca/MedImmune; Bristol-Myers Squibb; EISAI; Elevar Therapeutics; Exelixis; Merck; Qurient; Roche/Genentech; Senti Biosciences; SERVIER; TERUMO
Consulting or Advisory Role - Agenus; AstraZeneca/MedImmune; Bristol-Myers Squibb; Eisai; Elevar Therapeutics; Exelixis; Genentech; Merck; Qurient; Roche; Senti Biosciences; SERVIER; TERUMO
Research Funding - Astex Pharmaceuticals; AstraZeneca; Auransa; Fulgent Genetics
Travel, Accommodations, Expenses - Affimed Therapeutics
 
Nehal Lakhani
Research Funding - Alexo Therapeutics (Inst); Alkermes (Inst); Alkermes/Mural Oncology (Inst); Alpine Immune Sciences (Inst); Alpine Immune Sciences (Inst); Apexian Pharmaceuticals (Inst); Arcus Ventures (Inst); Artios (Inst); Ascentage Pharma (Inst); Astellas Pharma (Inst); BeiGene (Inst); BioNTech SE (Inst); Biosplice (Inst); Celgene (Inst); Celgene (Inst); Constellation Pharmaceuticals (Inst); Coordination Therapeutics (Inst); CytomX Therapeutics (Inst); Epizyme (Inst); Forty Seven (Inst); Genmab (Inst); Genmab (Inst); Gilead Sciences (Inst); GlaxoSmithKline (Inst); Helsinn Therapeutics (Inst); Ikena Oncology (Inst); Ikena Oncology (Inst); Incyte (Inst); InhibRx (Inst); Innovent Biologics (Inst); Janssen (Inst); Jounce Therapeutics (Inst); KSQ Therapeutics (Inst); LAM Therapeutics (Inst); Lilly (Inst); Livzon (Inst); Loxo (Inst); Macrogenics (Inst); Merck (Inst); Mersana (Inst); Northern Biologics (Inst); Odonate Therapeutics (Inst); Pfizer (Inst); Quanta Therapeutics (Inst); Regeneron (Inst); Repare Therapeutics (Inst); Sapience Therapeutics (Inst); Sapience Therapeutics (Inst); Seagen (Inst); Servier (Inst); Shattuck Labs (Inst); SK Life Sciences (Inst); Symphogen (Inst); Tesaro (Inst); Tizona Therapeutics, Inc. (Inst)
 
Jason Henry
Employment - HCA Healthcare
Stock and Other Ownership Interests - HCA Healthcare
Research Funding - Abbisko (Inst); ABL Bio (Inst); accutar biotech (Inst); ADC Therapeutics (Inst); Agenus (Inst); Aileron Therapeutics (Inst); Amgen (Inst); Artios (Inst); AstraZeneca/Merck (Inst); Bicycle Therapeutics (Inst); BioAtla (Inst); Bioinvent (Inst); Biosplice (Inst); Black Diamond Therapeutics (Inst); Boehringer Ingelheim (Inst); cyteir (Inst); DaiichI Sankyo (Inst); Daiichi Sankyo/Lilly (Inst); Epizyme (Inst); Erasca, Inc (Inst); Exelixis (Inst); Fujifilm (Inst); GlaxoSmithKline (Inst); Hutchison MediPharma (Inst); Iconic Therapeutics (Inst); Iconic Therapeutics (Inst); Iconic Therapeutics (Inst); IgM Biosciences (Inst); Immunitas (Inst); Immunogen (Inst); Immunogen (Inst); Jacobio (Inst); Jazz Pharmaceuticals (Inst); Jounce Therapeutics (Inst); Jubilant Pharmaceuticals (Inst); Jubilant Pharmaceuticals (Inst); Lilly (Inst); Loxo (Inst); Merck (Inst); Metabomed (Inst); Mirati Therapeutics (Inst); Molecular Templates (Inst); Navire (Inst); NiKang Therapeutics (Inst); Oncorus (Inst); Poseida therapeutics (Inst); Prelude Therapeutics (Inst); PureTech (Inst); Pyramid Biosciences (Inst); Pyxis (Inst); RasCal (Inst); Regeneron (Inst); Relay Therapeutics (Inst); Rgenix (Inst); Ribon Therapeutics (Inst); Sapience Therapeutics (Inst); Sarah Cannon Research Institute (Inst); Sarah Cannon Research Institute (Inst); Seagan (Inst); Simcha Therapeutics (Inst); Sirnaomics (Inst); Stingthera (Inst); StingThera (Inst); Synthorx (Inst); Synthorx (Inst); Takeda (Inst); Takeda (Inst); Tallac Therapeutics (Inst); Tarveda Therapeutics (Inst); Teneothree (Inst); Tesaro (Inst); Turning Point Therapeutics (Inst); Xencor (Inst)
Travel, Accommodations, Expenses - HCA/Sarah Cannon (Inst)
 
Steven Powell
Consulting or Advisory Role - Bristol-Myers Squibb (Inst)
Speakers' Bureau - Alkermes (Inst)
Research Funding - Actuate Therapeutics (Inst); AstraZeneca/MedImmune (Inst); Bristol-Myers Squibb (Inst); Celgene (Inst); Genentech/Roche (Inst); Incyte (Inst); Janssen Research & Development (Inst); Merck Sharp & Dohme (Inst); Molecular Templates (Inst); Novartis (Inst); Pfizer (Inst); Seagen (Inst); Sensei Biotherapeutics (Inst); Sorrento Therapeutics (Inst); Takeda (Inst); Vyriad (Inst)
 
Niharika Mettu
Consulting or Advisory Role - Eclipse Life Sciences (I); Eyedea Bio (I); Iveric Bio (I); Pulsar Life Sciences (I)
Research Funding - Actuate Therapeutics (Inst); Adanate (Inst); Amgen (Inst); Aravive (Inst); BioMed Valley Discoveries (Inst); Compass Therapeutics (Inst); Merck (Inst); NGM Biopharmaceuticals; Nucana (Inst); Repare Therapeutics (Inst); Sapience Therapeutics (Inst)
 
Joyce Gakuria
No Relationships to Disclose
 
Franco Abbate
Employment - Sapience Therapeutics
Stock and Other Ownership Interests - Sapience Therapeutics
Honoraria - Sapience Therapeutics
Travel, Accommodations, Expenses - Sapience Therapeutics
 
Paolo Nuciforo
Honoraria - Bayer; MSD Oncology; Novartis; Targos GmbH
Consulting or Advisory Role - Bayer; MSD Oncology; Targos GmbH
Travel, Accommodations, Expenses - Novartis
 
Jim Rotolo
Employment - Sapience Therapeutics
Leadership - Sapience Therapeutics
Stock and Other Ownership Interests - Sapience Therapeutics
Honoraria - Sapience Therapeutics
Patents, Royalties, Other Intellectual Property - Sapience Therapeutics
Travel, Accommodations, Expenses - Sapience Therapeutics
 
Abi Vainstein Haras
Employment - BioLineRx; Sapience Therapeutics
Leadership - Sapience Therapeutics
Stock and Other Ownership Interests - BioLineRx; Sapience Therapeutics
Honoraria - BioLineRx; Sapience Therapeutics
Consulting or Advisory Role - BioLineRx
Travel, Accommodations, Expenses - BioLineRx; Sapience Therapeutics