The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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Preliminary results of a phase 1 study of LB1908, an autologous Claudin 18.2–targeted chimeric antigen receptor T-cell product, in patients with advanced gastroesophageal adenocarcinoma.
 
David Zhen
Consulting or Advisory Role - Boehringer Ingelheim; Bristol Myers Squibb; Exelixis; Jazz Pharmaceuticals; Legend Biotech; Medigene
Research Funding - A2 Biotherapeutics (Inst); AstraZeneca (Inst); Bayer (Inst); Bristol Myers Squibb (Inst); Clasp Therapeutics (Inst); Cornerstone Pharmaceuticals (Inst); Daiichi Sankyo/Astra Zeneca (Inst); Genentech (Inst); Legend Biotech (Inst); Lilly (Inst); Medigene (Inst); Merck (Inst); Pfizer (Inst)
 
Christos Fountzilas
Research Funding - Amgen (Inst); Aravive (Inst); Astellas Pharma (Inst); AstraZeneca (Inst); Bellicum Pharmaceuticals (Inst); Biomea Fusion (Inst); Bristol-Myers Squibb/Ono Pharmaceutical (Inst); Corcept Therapeutics (Inst); CrystalGenomics (Inst); Dragonfly Therapeutics (Inst); ERYTECH Pharma (Inst); Ipsen (Inst); Kadmon (Inst); Legend Biotech USA Inc (Inst); Lilly (Inst); Merck (Inst); Pfizer (Inst); Rafael Pharmaceuticals (Inst); Sanofi (Inst); Seagen (Inst); Taiho Oncology (Inst); TransThera Biosciences (Inst); Valar Labs (Inst)
Travel, Accommodations, Expenses - CG Pharmaceuticals
 
Richard Maziarz
Stock and Other Ownership Interests - Abbvie; Autolus; Bristol-Myers Squibb
Honoraria - Crispr Therapeutics; Incyte; Kite, a Gilead Company; Novartis
Consulting or Advisory Role - Artiva; Novartis; Oricell Therapeutics
Research Funding - Novartis
Patents, Royalties, Other Intellectual Property - Athersys
 
Emerson Chen
Consulting or Advisory Role - MDoutlook
Research Funding - G1 Therapeutics (Inst); Ipsen Bioscience Inc. (Inst); Jazz Pharmaceuticals (Inst); Merck Sharp & Dohme Llc (Inst); Taiho Oncology (Inst)
Travel, Accommodations, Expenses - Daiichi Sankyo/Astra Zeneca
Other Relationship - Horizon CME
 
Michael Gibson
Stock and Other Ownership Interests - PapiVax Biotech, Inc.; PharmaJet
Honoraria - Astellas Pharma; Coherus Biosciences; Daiichi Sankyo/Lilly; Regeneron
Consulting or Advisory Role - Abbvie; regeneron; UpToDate
Research Funding - Daiichi Sankyo/Lilly (Inst); Juntendo University Medical Center (Inst); PapiVax Biotech, Inc. (Inst)
 
Ben Oshrine
Employment - ImmunoGen; Legend Biotech
Stock and Other Ownership Interests - ImmunoGen; Legend Biotech
Expert Testimony - Children's Hospital of Atlanta
 
Mythili Koneru
Employment - Legend Biotech
Stock and Other Ownership Interests - Legend Biotech
 
Sahista Vahora
Employment - Legend Biotech
Stock and Other Ownership Interests - Abbvie; Bristol-Myers Squibb; Intuitive Surgical; Johnson & Johnson; Legend Biotech; Legend Biotech (Inst); Pfizer; Walgreens
 
Da Xu
Employment - Legend Biotech
Stock and Other Ownership Interests - Legend Biotech; Legend Biotech (Inst)
 
Anthony Shields
Consulting or Advisory Role - Caris Life Sciences; Cogent Biosciences; ImaginAb; Legend Biotech
Speakers' Bureau - Caris Life Sciences
Research Funding - Abbisko Therapeutics (Inst); Alkermes; Amal Therapeutics (Inst); Astellas Pharma; AstraZeneca; Bayer; Boehringer Ingelheim; Boston Biomedical; Caris Life Sciences; Daiichi Sankyo; Eisai; Esperas Pharma; Esperas Pharma; Exelixis; Five Prime Therapeutics; Gritstone Bio (Inst); H3 Biomedicine; Halozyme; Hutchison China Meditech; IconOVir Bio (Inst); ImaginAb; Incyte; Inovio Pharmaceuticals; Jiangsu Alphamab Biopharmaceuticals; Lexicon; LSK BioPharma; MSK Pharma; Nouscom; Nuvation Bio (Inst); Plexxikon; Repertoire Immune Medicines; Seagen; Shanghai HaiHe Pharmaceutical; Sorrento Therapeutics (Inst); SQZ Biotechnology (Inst); Taiho Pharmaceutical; Telix Pharmaceuticals; TheraBionic (Inst); TopAlliance BioSciences Inc (Inst); Torque (Inst); Xencor
Travel, Accommodations, Expenses - Caris Life Sciences; GE Healthcare; ImaginAb; Inovio Pharmaceuticals; TransTarget